List of works by Andrew Donson

Aurora kinase A as a rational target for therapy in glioblastoma.

scientific article published on July 2010

Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors

scientific article published on 13 May 2014

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

scientific article

CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy

scientific article

Characterization of distinct immunophenotypes across pediatric brain tumor types

scientific article published on 27 September 2013

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

scientific article published on 19 July 2016

Clinical and molecular characteristics of congenital glioblastoma

scientific article

Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas

scientific article

EP-04ACTIVATION OF THE IL6/STAT3 PATHWAY IN CHILDHOOD EPENDYMOMA IS ASSOCIATED WITH A PRO-INFLAMMATORY TUMOR MICROENVIRONMENT AND A POOR PROGNOSIS.

scientific article published on 21 April 2015

EPN-25ACTIVATION OF THE IL6/STAT3 PATHWAY IN CHILDHOOD EPENDYMOMA IS ASSOCIATED WITH A PRO-INFLAMMATORY TUMOR MICROENVIRONMENT AND A POOR PROGNOSIS.

scientific article published on 30 May 2016

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

scientific article (publication date: May 2014)

Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastoma

scientific article

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival

scientific article published on 23 September 2011

Histone deacetylase inhibition decreases proliferation and potentiates the effect of ionizing radiation in atypical teratoid/rhabdoid tumor cells.

scientific article published on 8 December 2011

IM-01ANTI-TUMOR EFFECT OF TRASTUZUMAB, GM-CSF AND IL-2 COMBINATORIAL THERAPY IN PEDIATRIC EPENDYMOMA.

scientific article published on 21 April 2015

IM-08INFLAMMATION DRIVER, NF-kB, IS ASSOCIATED WITH POOR OUTCOME GROUP A EPENDYMOMA AND REGULATES A KEY IMMUNE SUPPRESSIVE SIGNALING PATHWAY INVOLVED IN THE TUMOR MICROENVIRONMENT.

scientific article published on 21 April 2015

Identification of targets for rational pharmacological therapy in childhood craniopharyngioma

scientific article published on 21 May 2015

Immune gene and cell enrichment is associated with a good prognosis in ependymoma.

scientific article

Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors.

scientific article

Inhibition of Aurora Kinase A enhances chemosensitivity of medulloblastoma cell lines.

scientific article published on July 2010

Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity

scientific article

Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells

scientific article

Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.

scientific article

Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.

scientific article published on 24 March 2014

Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma

scientific article

MB-22CHECKPOINT KINASE 1 EXPRESSION IS AN ADVERSE PROGNOSTIC MARKER AND THERAPEUTIC TARGET IN MYC-DRIVEN MEDULLOBLASTOMA.

scientific article published on 21 April 2015

MPS1 kinase as a potential therapeutic target in medulloblastoma.

scientific article published on 12 September 2016

Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma

scientific article

Pediatric brainstem gangliogliomas show BRAF(V600E) mutation in a high percentage of cases

scientific article

Pediatric brainstem gangliogliomas show overexpression of neuropeptide prepronociceptin (PNOC) by microarray and immunohistochemistry

scientific article

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes

scientific article published on 4 February 2013

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

scientific article

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

scientific article

Survey of MicroRNA expression in pediatric brain tumors

scientific article

Unique molecular characteristics of pediatric myxopapillary ependymoma

scientific article

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