List of works - Kathryn Aston-Mourney

Adipocytokines as features of the metabolic syndrome determined using confirmatory factor analysis

scientific article published on 25 March 2013

Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress

scientific article published on 08 April 2009

Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets

scientific article published on 11 November 2008

Class IIa HDACs do not influence beta-cell function under normal or high glucose conditions

scientific article published on 21 May 2019

Copper Ionophores as Novel Antiobesity Therapeutics

scientific article published on 27 October 2020

Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet

scientific article

Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets.

scientific article published on 12 April 2011

Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function

scientific article published on 28 March 2008

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction

scientific article published on August 2005

Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.

scientific article published on 6 October 2007

Investigational agents that protect pancreatic islet beta-cells from failure

scientific article

Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide

scientific article published on 10 December 2012

Neprilysin impedes islet amyloid formation by inhibition of fibril formation rather than peptide degradation

scientific article

One year of sitagliptin treatment protects against islet amyloid-associated β-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice

scientific article published on 04 June 2013

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

scientific article published on 16 January 2009

Rosiglitazone treatment does not decrease amyloid deposition in transplanted islets from transgenic mice expressing human islet amyloid polypeptide

scientific article published on 25 September 2012

Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice

scientific article

The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets.

scientific article

Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin

scientific article published on 2 February 2008

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.

scientific article published on 26 October 2011

β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition

scientific article

List of works by Kathryn Aston-Mourney

Adipocytokines as features of the metabolic syndrome determined using confirmatory factor analysis

Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress

Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets

Class IIa HDACs do not influence beta-cell function under normal or high glucose conditions

Copper Ionophores as Novel Antiobesity Therapeutics

Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet

Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets.

Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction

Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.

Investigational agents that protect pancreatic islet beta-cells from failure

Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide

Neprilysin impedes islet amyloid formation by inhibition of fibril formation rather than peptide degradation

One year of sitagliptin treatment protects against islet amyloid-associated β-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

Rosiglitazone treatment does not decrease amyloid deposition in transplanted islets from transgenic mice expressing human islet amyloid polypeptide

Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice

The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets.

Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.

β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition