List of works - Andisheh Abedini

A Single-Point Mutation Converts the Highly Amyloidogenic Human Islet Amyloid Polypeptide into a Potent Fibrillization Inhibitor

scientific article published on 28 August 2007

A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides

scientific article published on 12 July 2009

A role for helical intermediates in amyloid formation by natively unfolded polypeptides?

scientific article published on 10 February 2009

Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology

scientific article published on 22 December 2012

Amyloid formation by pro-islet amyloid polypeptide processing intermediates: examination of the role of protein heparan sulfate interactions and implications for islet amyloid formation in type 2 diabetes

scientific article published on 9 October 2007

Amyloidogenicity, Cytotoxicity, and Receptor Activity of Bovine Amylin: Implications for Xenobiotic Transplantation and the Design of Nontoxic Amylin Variants

scientific article published on 22 August 2018

Analysis of Baboon IAPP Provides Insight into Amyloidogenicity and Cytotoxicity of Human IAPP

scientific article published on 03 January 2020

Analysis of the role of the conserved disulfide in amyloid formation by human IAPP in homogenous and heterogeneous environments

scientific article

Aromatic Interactions Are Not Required for Amyloid Fibril Formation by Islet Amyloid Polypeptide but Do Influence the Rate of Fibril Formation and Fibril Morphology†

scientific article published on 21 February 2007

Characterization of the Heparin Binding Site in the N-Terminus of Human Pro-Islet Amyloid Polypeptide: Implications for Amyloid Formation†

scientific article published on 01 August 2006

Combination of kinetically selected inhibitors in trans leads to highly effective inhibition of amyloid formation

scientific article published on October 2010

Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP?

scientific article

Detection of Helical Intermediates During Amyloid Formation by Intrinsically Disordered Polypeptides and Proteins

scientific article published on January 2016

Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease

scientific article published on 01 January 2018

Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears?

scientific article

Incorporation of Pseudoproline Derivatives Allows the Facile Synthesis of Human IAPP, a Highly Amyloidogenic and Aggregation-Prone Polypeptide

scientific article published on 01 February 2005

Inflammation and obesity: STAMPing out insulin resistance?

scientific article published on 24 July 2007

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

scientific article

Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts

scientific article

Islet amyloid polypeptide toxicity and membrane interactions

scientific article

Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity

scientific article published on February 2013

Mechanisms of islet amyloidosis toxicity in type 2 diabetes

scientific article

RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes

scientific article published on 7 August 2015

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

scientific article published on 16 January 2018

Rational design of potent domain antibody inhibitors of amyloid fibril assembly

scientific article

Rationally designed, nontoxic, nonamyloidogenic analogues of human islet amyloid polypeptide with improved solubility

scientific article

Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide

scientific article published on 15 December 2005

Role of aromatic interactions in amyloid formation by peptides derived from human Amylin

scientific article published in December 2004

Sensitivity of amyloid formation by human islet amyloid polypeptide to mutations at residue 20

scientific article

The Receptor for Advanced Glycation Endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and Exploiting Common Ground for Novel Amyloidosis Therapies.

scientific article published on 17 April 2018

The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors

scientific article published on February 2010

The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.

scientific article

The role of His-18 in amyloid formation by human islet amyloid polypeptide

scientific article

The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation

scientific article

Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.

scientific article published on 23 May 2016

List of works by Andisheh Abedini

A Single-Point Mutation Converts the Highly Amyloidogenic Human Islet Amyloid Polypeptide into a Potent Fibrillization Inhibitor

A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides

A role for helical intermediates in amyloid formation by natively unfolded polypeptides?

Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology

Amyloid formation by pro-islet amyloid polypeptide processing intermediates: examination of the role of protein heparan sulfate interactions and implications for islet amyloid formation in type 2 diabetes

Amyloidogenicity, Cytotoxicity, and Receptor Activity of Bovine Amylin: Implications for Xenobiotic Transplantation and the Design of Nontoxic Amylin Variants

Analysis of Baboon IAPP Provides Insight into Amyloidogenicity and Cytotoxicity of Human IAPP

Analysis of the role of the conserved disulfide in amyloid formation by human IAPP in homogenous and heterogeneous environments

Aromatic Interactions Are Not Required for Amyloid Fibril Formation by Islet Amyloid Polypeptide but Do Influence the Rate of Fibril Formation and Fibril Morphology†

Characterization of the Heparin Binding Site in the N-Terminus of Human Pro-Islet Amyloid Polypeptide: Implications for Amyloid Formation†

Combination of kinetically selected inhibitors in trans leads to highly effective inhibition of amyloid formation

Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP?

Detection of Helical Intermediates During Amyloid Formation by Intrinsically Disordered Polypeptides and Proteins

Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease

Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears?

Incorporation of Pseudoproline Derivatives Allows the Facile Synthesis of Human IAPP, a Highly Amyloidogenic and Aggregation-Prone Polypeptide

Inflammation and obesity: STAMPing out insulin resistance?

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts

Islet amyloid polypeptide toxicity and membrane interactions

Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity

Mechanisms of islet amyloidosis toxicity in type 2 diabetes

RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

Rational design of potent domain antibody inhibitors of amyloid fibril assembly

Rationally designed, nontoxic, nonamyloidogenic analogues of human islet amyloid polypeptide with improved solubility

Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide

Role of aromatic interactions in amyloid formation by peptides derived from human Amylin

Sensitivity of amyloid formation by human islet amyloid polypeptide to mutations at residue 20

The Receptor for Advanced Glycation Endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and Exploiting Common Ground for Novel Amyloidosis Therapies.

The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors

The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.

The role of His-18 in amyloid formation by human islet amyloid polypeptide

The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation

Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.