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List of works by Andras Gruber

A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo

scientific article (publication date: 11 November 2010)

Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor

scientific article

Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes

scientific article

Activated protein C correlates inversely with thrombin levels in resting healthy individuals.

scientific article published in September 1997

Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo

scientific article published on 13 April 2017

Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates

scientific article published on 11 February 2020

Antithrombotic activity of protein S infused without activated protein C in a baboon thrombosis model

scientific article published on 28 February 2012

Coagulation Factor XI Promotes Distal Platelet Activation and Single Platelet Consumption in the Bloodstream Under Shear Flow.

scientific article published on 14 January 2016

Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice

scientific article published on January 2014

Differential Roles for the Coagulation Factors XI and XII in Regulating the Physical Biology of Fibrin.

scientific article published on 8 December 2016

Evaluation of the Antihemostatic and Antithrombotic Effects of Lowering Coagulation Factor VII Levels in a Non-human Primate

scientific article published on 23 March 2020

Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7.

scientific article published on August 2010

Evidence for factor IX-independent roles for factor XIa in blood coagulation.

scientific article published on December 2013

Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice

scientific article (publication date: 2016)

Factor XI and contact activation as targets for antithrombotic therapy

scientific article

Factor XI as a Therapeutic Target.

scientific article published on 12 May 2016

Factor XI contributes to myocardial ischemia-reperfusion injury in mice

scientific article published on 01 January 2018

Factor XI contributes to thrombin generation in the absence of factor XII

scientific article published on 07 April 2009

Factor XI-deficient mice display reduced inflammation, coagulopathy, and bacterial growth during listeriosis

scientific article

Factor XI-dependence of surface- and tissue factor-initiated thrombus propagation in primates

scientific article published on 10 April 2003

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

scientific article published on 09 January 2014

Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates.

scientific article published on July 2013

Functional deficiency of protein C and skin necrosis in multiple myeloma

scientific article published on 01 May 1986

Hemostatic effect of activated factor VII without promotion of thrombus growth in melagatran-anticoagulated primates.

scientific article published on 31 January 2006

Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2).

scientific article published on 06 August 2009

In vivo optical imaging of revascularization after brain trauma in mice.

scientific article

Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.

scientific article published on September 2012

Inhibition of contact-mediated activation of factor XI protects baboons against S aureus–induced organ damage and death

scientific article published on 01 February 2019

Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor.

scientific article published on July 2008

Limited generation of activated protein C during infusion of the protein C activator thrombin analog W215A/E217A in primates.

scientific article published in February 2006

Nucleic acids as cofactors for factor XI and prekallikrein activation: Different roles for high-molecular-weight kininogen

scientific article published on 26 January 2017

Oral administration of Bruton's tyrosine kinase inhibitors impairs GPVI-mediated platelet function.

scientific article published on 09 December 2015

Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways

scientific article published on 19 June 2018

Phosphatidylserine index as a marker of the procoagulant phenotype of acute myelogenous leukemia cells

scientific article published on 08 October 2013

Plasma contact factors as therapeutic targets

scientific article published on 12 April 2018

Plasma kallikrein: novel functions for an old protease

scientific article published on 03 May 2012

Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI.

scientific article

Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension

scientific article published in February 2017

Promotion of experimental thrombus formation by the procoagulant activity of breast cancer cells.

scientific article published on 7 February 2011

Protein C pathway impairment in nonsymptomatic cigarette smokers

scientific article published on 01 July 2002

Protein C supports platelet binding and activation under flow: role of glycoprotein Ib and apolipoprotein E receptor 2.

scientific article published in June 2008

Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates.

scientific article published on 16 January 2007

Removal of the C-Terminal Domains of ADAMTS13 by Activated Coagulation Factor XI induces Platelet Adhesion on Endothelial Cells under Flow Conditions.

scientific article published on 20 December 2017

Reversal of rivaroxaban anticoagulation by haemostatic agents in rats and primates.

scientific article published on 2 May 2013

Role of coagulation in the recruitment of colon adenocarcinoma cells to thrombus under shear.

scientific article

Selective factor VIII activation by the tissue factor-factor VIIa-factor Xa complex

scientific article published on 20 July 2017

Size matters

scientific article published on 01 December 2011

Soluble thrombomodulin is antithrombotic in the presence of neutralising antibodies to protein C and reduces circulating activated protein C levels in primates

scientific article published on 01 January 2006

Sustained-release morphine for epidural analgesia in rats.

scientific article

The Formation of Microthrombi in Parenchymal Microvessels after Traumatic Brain Injury Is Independent of Coagulation Factor XI.

scientific article published on 17 February 2016

The role of the contact pathway in thrombus propagation

scientific article

The thrombin mutant W215A/E217A shows safe and potent anticoagulant and antithrombotic effects in vivo

scientific article published on 17 June 2002

Three dimensional optical angiography

scientific article published on 01 April 2007

Thrombin mutant W215A/E217A acts as a platelet GPIb antagonist.

scientific article published on 25 October 2007

Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis.

scientific article

WEDGE: an anticoagulant thrombin mutant produced by autoactivation.

scientific article

α2-Macroglobulin Is a Significant In Vivo Inhibitor of Activated Protein C and Low APC:α2M Levels Are Associated with Venous Thromboembolism.

scientific article published on 15 February 2018

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