List of works - Carol Feghali-Bostwick

An endostatin-derived peptide orally exerts anti-fibrotic activity in a murine pulmonary fibrosis model

scientific article

Analysis of systemic sclerosis in twins reveals low concordance for disease and high concordance for the presence of antinuclear antibodies

scientific article published on July 2003

Autologous bone marrow-derived rat mesenchymal stem cells promote PDX-1 and insulin expression in the islets, alter T cell cytokine pattern and preserve regulatory T cells in the periphery and induce sustained normoglycemia

scientific article

Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension

scientific article

Characterization of human PDGFRβ-positive pericytes from IPF and non-IPF lungs

scientific article published on 18 October 2018

Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-β1 Signaling ⬇️

scientific article published on July 23, 2012

Differences in Right Ventricular Functional Changes during Treatment between Systemic Sclerosis-associated Pulmonary Arterial Hypertension and Idiopathic Pulmonary Arterial Hypertension

scientific article

Distinct PKC isoforms mediate cell survival and DNA synthesis in thrombin-induced myofibroblasts.

scientific article

Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy

scientific article

Effect of culture conditions on microRNA expression in primary adult control and COPD lung fibroblasts in vitro

scientific article published in January 2015

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

scientific article

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease

scientific article published on 11 September 2015

Endothelial GATA-6 deficiency promotes pulmonary arterial hypertension

scientific article published on 11 April 2013

Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis

scientific article published on 17 July 2019

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice

scientific article published on 9 December 2015

Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes

scientific article published on 11 July 2014

IGFBP-5 Promotes Fibrosis Independently of Its Translocation to the Nucleus and Its Interaction with Nucleolin and IGF.

scientific article published on 23 June 2015

IGFBP-5 Promotes Fibrosis via Increasing Its Own Expression and That of Other Pro-fibrotic Mediators

Induction of a Th17 Phenotype in Human Skin-A Mimic of Dermal Inflammatory Diseases

scientific article published on 04 June 2019

Insulin-like growth factor (IGF)-II- mediated fibrosis in pathogenic lung conditions

scientific article published on 25 November 2019

Interleukin‐13–producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis ⬇️

scientific article published on January 1, 2013

Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis

scientific article published on 01 June 2019

Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation

scientific article

Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling

scientific article published on 30 November 2012

Molecular Profiling Of Lung Tissues And Primary Fibroblasts From Patients With Systemic Sclerosis

Novel classification for global gene signature model for predicting severity of systemic sclerosis.

scientific article published on 20 June 2018

Optimization of a murine and human tissue model to recapitulate dermal and pulmonary features of systemic sclerosis

scientific article

Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-β1 signaling in interstitial lung disease

scientific article published on 09 December 2013

PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis

scientific article

Phenotypic Characterization of Transgenic Mice Expressing Human IGFBP-5

scientific article published on 30 December 2020

Phosphodiesterase-4 inhibition augments human lung fibroblast vascular endothelial growth factor production induced by prostaglandin E2.

scientific article published in October 2013

Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis

scientific article published on 8 September 2016

Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease

scientific article published on 7 September 2017

Review: Frontiers of Antifibrotic Therapy in Systemic Sclerosis

scientific article published on 16 September 2016

Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?

scientific article

Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis

scientific article published on 6 December 2012

Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis

scientific article

Skin gene expression correlates of severity of interstitial lung disease in systemic sclerosis

scientific article published in November 2013

Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma

scientific article published on 4 September 2008

Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy.

scientific article published on 18 August 2015

The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis

scientific article

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

scientific article published on 7 November 2012

Transcriptome analysis reveals differential splicing events in IPF lung tissue

scientific article

Transcriptome analysis reveals differential splicing events in IPF lung tissue

scientific article published on 19 March 2014

Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis

scientific article

Vitamin D modulates prostaglandin E2 synthesis and degradation in human lung fibroblasts

scientific article published in January 2014

WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis

scientific article

List of works by Carol Feghali-Bostwick

An endostatin-derived peptide orally exerts anti-fibrotic activity in a murine pulmonary fibrosis model

Analysis of systemic sclerosis in twins reveals low concordance for disease and high concordance for the presence of antinuclear antibodies

Autologous bone marrow-derived rat mesenchymal stem cells promote PDX-1 and insulin expression in the islets, alter T cell cytokine pattern and preserve regulatory T cells in the periphery and induce sustained normoglycemia

Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension

Characterization of human PDGFRβ-positive pericytes from IPF and non-IPF lungs

Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-β1 Signaling ⬇️

Differences in Right Ventricular Functional Changes during Treatment between Systemic Sclerosis-associated Pulmonary Arterial Hypertension and Idiopathic Pulmonary Arterial Hypertension

Distinct PKC isoforms mediate cell survival and DNA synthesis in thrombin-induced myofibroblasts.

Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy

Effect of culture conditions on microRNA expression in primary adult control and COPD lung fibroblasts in vitro

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease

Endothelial GATA-6 deficiency promotes pulmonary arterial hypertension

Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice

Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes

IGFBP-5 Promotes Fibrosis Independently of Its Translocation to the Nucleus and Its Interaction with Nucleolin and IGF.

IGFBP-5 Promotes Fibrosis via Increasing Its Own Expression and That of Other Pro-fibrotic Mediators

Induction of a Th17 Phenotype in Human Skin-A Mimic of Dermal Inflammatory Diseases

Insulin-like growth factor (IGF)-II- mediated fibrosis in pathogenic lung conditions

Interleukin‐13–producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis ⬇️

Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis

Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation

Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling

Molecular Profiling Of Lung Tissues And Primary Fibroblasts From Patients With Systemic Sclerosis

Novel classification for global gene signature model for predicting severity of systemic sclerosis.

Optimization of a murine and human tissue model to recapitulate dermal and pulmonary features of systemic sclerosis

Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-β1 signaling in interstitial lung disease

PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis

Phenotypic Characterization of Transgenic Mice Expressing Human IGFBP-5

Phosphodiesterase-4 inhibition augments human lung fibroblast vascular endothelial growth factor production induced by prostaglandin E2.

Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis

Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease

Review: Frontiers of Antifibrotic Therapy in Systemic Sclerosis

Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?

Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis

Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis

Skin gene expression correlates of severity of interstitial lung disease in systemic sclerosis

Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma

Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy.

The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

Transcriptome analysis reveals differential splicing events in IPF lung tissue

Transcriptome analysis reveals differential splicing events in IPF lung tissue

Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis

Vitamin D modulates prostaglandin E2 synthesis and degradation in human lung fibroblasts

WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis