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List of works by Maria Sancha Santos

A second look into the oxidant mechanisms in Alzheimer's disease

scientific article

Alterations of liver mitochondrial bioenergetics in diabetic Goto-Kakizaki rats

scientific article published on 01 September 1999

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

scientific article published on February 2008

Alzheimer's disease: a lesson from mitochondrial dysfunction.

scientific article published on October 2007

Amyloid beta-peptide promotes permeability transition pore in brain mitochondria

scientific article published in December 2001

An Aqueous Extract of Valerian Influences the Transport of GABA in Synaptosomes

scientific article published on 01 June 1994

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

scientific article published on January 2009

Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes.

scientific article published on 20 February 2007

Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen.

scientific article

Calcium-dependent mitochondrial permeability transition is augmented in the kidney of Goto-Kakizaki diabetic rat

scientific article published on 01 March 2004

Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity.

scientific article

Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria.

scientific article published in October 2005

Chromium(VI) interaction with plant and animal mitochondrial bioenergetics: a comparative study.

scientific article

Cisplatin impairs rat liver mitochondrial functions by inducing changes on membrane ion permeability: prevention by thiol group protecting agents.

scientific article published on 30 January 2009

CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats.

scientific article published on 29 August 2005

Comparative effects of 3,4-methylenedioxymethamphetamine and 4-methylthioamphetamine on rat liver mitochondrial function.

scientific article published on 6 February 2010

Comparative effects of three 1,4-dihydropyridine derivatives [OSI-1210, OSI-1211 (etaftoron), and OSI-3802] on rat liver mitochondrial bioenergetics and on the physical properties of membrane lipid bilayers: relevance to the length of the alkoxyl ch

scientific article published on 15 March 2008

Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia.

scientific article published on 8 July 2010

Decreased susceptibility to lipid peroxidation of Goto-Kakizaki rats: relationship to mitochondrial antioxidant capacity.

scientific article published on January 1999

Diabetes and mitochondrial oxidative stress: a study using heart mitochondria from the diabetic Goto-Kakizaki rat.

scientific article published on April 2003

Distinct glycolysis inhibitors determine retinal cell sensitivity to glutamate-mediated injury

scientific article published in March 1999

Doxorubicin-induced thiol-dependent alteration of cardiac mitochondrial permeability transition and respiration.

scientific article published in February 2006

Doxorubicin: the good, the bad and the ugly effect

scientific article published on September 2009

Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

scientific article

Effect of glucose deprivation and acute glutamate exposure in cultured retinal cells.

scientific article published in September 1998

Effects of 1,4-dihydropyridine derivatives (cerebrocrast, gammapyrone, glutapyrone, and diethone) on mitochondrial bioenergetics and oxidative stress: a comparative study

scientific article published in August 2003

Effects of estrogen in the brain: is it a neuroprotective agent in Alzheimer's disease?

scientific article published on July 2010

Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes

scientific article published on 24 July 2006

Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats

scientific article published in November 2003

Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats.

scientific article

Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability.

scientific article published in January 2004

Glutamate regulates the viability of retinal cells in culture

scientific article published in March 2001

Higher efficiency of the liver phosphorylative system in diabetic Goto-Kakizaki (GK) rats.

scientific article published on September 1999

Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with alpha-naphthyl-isothiocyanate (ANIT).

scientific article published in August 2003

Hydroxytamoxifen protects against oxidative stress in brain mitochondria.

scientific article

Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins.

scientific article published on May 2013

In vitro study of the interaction of Tilia europeae L. aqueous extract with GABAA receptors in rat brain

Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure.

scientific article published in June 2003

Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress

scientific article published on 01 June 1999

Influence of vitamin E succinate on retinal cell survival

scientific article published in July 1998

Insulin affects synaptosomal GABA and glutamate transport under oxidative stress conditions

scientific article

Insulin attenuates diabetes-related mitochondrial alterations: a comparative study.

scientific article published in May 2006

Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

scientific article

Insulin protects against amyloid beta-peptide toxicity in brain mitochondria of diabetic rats.

scientific article published on April 2005

Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.

scientific article published in October 2006

Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants

scientific article published on 01 June 1999

Mannosylglycerate is essential for osmotic adjustment in Thermus thermophilus strains HB27 and RQ-1.

scientific article published on 29 August 2007

Mechanism of inhibition of mitochondrial ATP synthase by 17β−Estradiol

scientific article published on 29 December 2012

Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview

scientific article

Metabolic inhibition increases glutamate susceptibility on a PC12 cell line

Metformin promotes isolated rat liver mitochondria impairment.

scientific article published on 2 October 2007

Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes.

scientific article published in July 2008

Mitochondria as a therapeutic target in Alzheimer's disease and diabetes

scientific article published on December 2009

Mitochondria as the target for mildronate's protective effects in azidothymidine (AZT)-induced toxicity of isolated rat liver mitochondria.

scientific article published in September 2008

Mitochondria from distinct tissues are differently affected by 17β-estradiol and tamoxifen

scientific article published on 13 October 2010

Mitochondrial Bioenergetics, Diabetes, and Aging: Top-Down Analysis Using the Diabetic Goto-Kakizaki (GK) Rat as a Model

scientific article published in January 2006

Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease

scientific article published in May 2013

Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria.

scientific article published on 29 March 2013

Mitochondrial dysfunction is the focus of quaternary ammonium surfactant toxicity to mammalian epithelial cells.

scientific article published on 25 March 2013

Mitochondrial function is not affected by renal morphological changes in diabetic goto-kakizaki rat.

scientific article published in January 2005

Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions.

scientific article published on 17 August 2007

Mitophagy in neurodegeneration: an opportunity for therapy?

scientific article published on June 2011

New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection

scientific article published on January 2011

Nitric oxide synthase activity and L-arginine metabolism in the retinas from streptozotocin-induced diabetic rats

scientific article published on 01 March 1998

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology

scientific article

Reduction in cardiac mitochondrial calcium loading capacity is observable during alpha-naphthylisothiocyanate-induced acute cholestasis: a clue for hepatic-derived cardiomyopathies?

scientific article published on January 2003

Resveratrol affects differently rat liver and brain mitochondrial bioenergetics and oxidative stress in vitro: investigation of the role of gender.

scientific article

Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets.

scientific article published on 26 August 2007

Stimulation of immunoreactive insulin release by glucose in rat brain synaptosomes.

scientific article published in January 1999

Supplementation of coenzyme Q10 and alpha-tocopherol lowers glycated hemoglobin level and lipid peroxidation in pancreas of diabetic rats.

scientific article published in February 2008

Susceptibility to beta-amyloid-induced toxicity is decreased in goto-kakizaki diabetic rats: involvement of oxidative stress.

scientific article published on January 2000

Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.

scientific article published on 12 January 2006

Tetrandrine concentrations not affecting oxidative phosphorylation protect rat liver mitochondria from oxidative stress

scientific article published on 28 June 2006

The Amount of GABA Present in Aqueous Extracts of Valerian is Sufficient to Account for [3H]GABA Release in Synaptosomes

scientific article published on 01 October 1994

The antiestrogen 4-hydroxytamoxifen protects against isotretinoin-induced permeability transition and bioenergetic dysfunction of liver mitochondria: comparison with tamoxifen.

scientific article published on 19 June 2013

The effect of soybean oil on glycaemic control in Goto-kakizaki rats, an animal model of type 2 diabetes.

scientific article published in May 2008

Therapeutic potential of oxidant mechanisms in Alzheimer's disease

scientific article

Toxicity assessment of the herbicide metolachlor comparative effects on bacterial and mitochondrial model systems.

scientific article published on 14 July 2009

Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies

scientific article

UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats.

scientific article published on 17 March 2013

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