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List of works by Jerome Mertens

APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.

scientific article published on 5 December 2013

Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients

scientific article published on 27 April 2021

Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases

scientific article published on 12 September 2018

Alzheimer's disease: distinct stages in neurogenic decline?

scientific article published in April 2015

Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons

scientific article published on 17 May 2019

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

scientific article published on 28 October 2015

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

scientific article published on 06 October 2015

Embryonic stem cell-based modeling of tau pathology in human neurons.

scientific article published on 13 March 2013

Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience

scientific article published on 19 May 2016

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease

scientific article published on 23 November 2011

Generating human serotonergic neurons in vitro: Methodological advances.

scientific article

Generation of functional human serotonergic neurons from fibroblasts

scientific article published on 27 October 2015

Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

scientific article published on 10 June 2016

Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile

scientific article published on 01 May 2018

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

scientific article published on August 2015

Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro

scientific article published on 13 April 2015

Next-generation disease modeling with direct conversion: a new path to old neurons

scientific article published on 26 November 2019

Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells.

scientific article published on 13 September 2017

One Big Step to a Neuron, Two Small Steps for miRNAs

scientific article published on 01 January 2021

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

scientific article published on 07 January 2019

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

scientific article published on 14 April 2012

Small molecules enable highly efficient neuronal conversion of human fibroblasts

scientific article

Take the shortcut - direct conversion of somatic cells into induced neural stem cells and their biomedical applications

scientific article published on 01 December 2019

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma

scientific article published on June 2013

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease

scientific article published on 01 September 2018

The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample

scientific article

The different moods of human serotonergic neurons.

scientific article published in January 2016

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