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List of works by Pierre-Olivier Frappart

A novel function of DNA repair molecule Nbs1 in terminal differentiation of the lens fibre cells and cataractogenesis

scientific article published on 21 June 2006

ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage.

scientific article published on 8 August 2017

ATR maintains select progenitors during nervous system development

scientific article published on 20 January 2012

ATRIP protects progenitor cells against DNA damage in vivo

scientific article published on 28 October 2020

An essential function for NBS1 in the prevention of ataxia and cerebellar defects

scientific journal article

An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability

scientific article published on 27 August 2004

Ataxia-telangiectasia and related diseases

scientific article published on January 2006

BRCA2 function and the central nervous system

scientific article published on 23 July 2007

BRCA2 is required for neurogenesis and suppression of medulloblastoma

scientific journal article

Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

scientific article published on 2 November 2006

Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis

scientific article published on 30 March 2016

Glucokinase is highly induced and glucose-6-phosphatase poorly repressed in liver of rainbow trout (Oncorhynchus mykiss) by a single meal with glucose

scientific article

Identification of differential gene expression in in vitro FSH treated pig granulosa cells using suppression subtractive hybridization.

scientific article published on 7 July 2006

Importance of organoids for personalized medicine

scientific article published on 12 November 2018

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway

scientific journal article

Mouse models of DNA double-strand break repair and neurological disease

scientific article published on 23 May 2008

Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.

scientific article

Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis

scientific journal article

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms

scientific article published on 25 January 2014

Nibrin functions in Ig class-switch recombination

scientific journal article

Pancreatic Ductal Adenocarcinoma (PDAC) Organoids: The Shining Light at the End of the Tunnel for Drug Response Prediction and Personalized Medicine

scientific article published on 24 September 2020

Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks

scientific article published on 19 May 2019

Poly(ADP-ribose) polymerase-1, a novel partner of progesterone receptors in endometrial cancer and its precursors

scientific article published in April 2004

Precision medicine meets the DNA damage response in pancreatic cancer.

scientific article published in January 2018

Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of Atrip-Seckel syndrome

scientific article published on 15 September 2020

RINT1 functions as a multitasking protein at the crossroads between genomic stability, ER homeostasis, and autophagy

scientific article published on July 2016

Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency

scholarly article

Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.

scientific article published on 18 September 2015

Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer

scientific article published on 01 September 2020

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