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List of works by Jerrold P. Weiss

"Endotoxin, TLR4 signaling and beyond"

scientific article published on 11 September 2014

17(R)-Resolvin D1 differentially regulates TLR4-mediated responses of primary human macrophages to purified LPS and live E. coli

scientific article

A novel role for the bactericidal/permeability increasing protein in interactions of gram-negative bacterial outer membrane blebs with dendritic cells

scientific article published on 01 August 2007

A synthetic lipid A mimetic modulates human TLR4 activity

scientific article

Amino acid sequence of a basic Agkistrodon halys blomhoffii phospholipase A2. Possible role of NH2-terminal lysines in action on phospholipids of Escherichia coli.

scientific article

An essential role for albumin in the interaction of endotoxin with lipopolysaccharide-binding protein and sCD14 and resultant cell activation

scientific article published on 7 October 2002

An opsonic function of the neutrophil bactericidal/permeability-increasing protein depends on both its N- and C-terminal domains.

scientific article published on September 1997

BPI-ANCA in transporter associated with antigen presentation (TAP) deficiency: possible role in susceptibility to Gram-negative bacterial infections

Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death

scientific article

Basis for the failure of Francisella tularensis lipopolysaccharide to prime human polymorphonuclear leukocytes.

scientific article published on June 2006

Bidirectional movement of a nascent polypeptide across microsomal membranes reveals requirements for vectorial translocation of proteins

scientific article published on October 2, 1992

Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B.

scientific article published on 15 August 2005

Cation-induced transcriptional regulation of the dlt operon of Staphylococcus aureus

scientific article published on May 2006

Cell-wall determinants of the bactericidal action of group IIA phospholipase A2 against Gram-positive bacteria.

scientific article

Characterization of Staphylococcus aureus Cardiolipin Synthases 1 and 2 and Their Contribution to Accumulation of Cardiolipin in Stationary Phase and within Phagocytes ⬇️

scientific article published on June 10, 2011

Characterization of monoclonal antibodies to human soluble MD-2 protein.

scientific article published in December 2006

Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming

scientific article published on 30 March 2018

Deacylation of lipopolysaccharide in whole Escherichia coli during destruction by cellular and extracellular components of a rabbit peritoneal inflammatory exudate

scientific article published on 01 December 1999

Diverse pro-inflammatory endotoxin recognition systems of mammalian innate immunity.

scientific article

Early and discrete changes in permeability of Escherichia coli and certain other gram-negative bacteria during killing by granulocytes.

scientific article

Effect of D-alanylation of (lipo)teichoic acids of Staphylococcus aureus on host secretory phospholipase A2 action before and after phagocytosis by human neutrophils

scientific article published on 01 April 2006

Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2

scientific article

Endotoxin-binding proteins modulate the susceptibility of bacterial endotoxin to deacylation by acyloxyacyl hydrolase

scientific article published on 16 January 2007

Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils.

scientific article published on September 1991

Endotoxin⋅albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

scientific article published on 12 October 2011

Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin

scientific article published on 24 March 2009

Evidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid A

scientific article

Evidence of a specific interaction between new synthetic antisepsis agents and CD14.

scientific article

Expression of functional D299G.T399I polymorphic variant of TLR4 depends more on coexpression of MD-2 than does wild-type TLR4.

scientific article published on 08 March 2010

Functional activity of MD-2 polymorphic variant is significantly different in soluble and TLR4-bound forms: decreased endotoxin binding by G56R MD-2 and its rescue by TLR4 ectodomain

scientific article

Hemin and a metabolic derivative coprohemin modulate the TLR4 pathway differently through different molecular targets

scientific article published on 14 May 2010

High-affinity caspase-4 binding to LPS presented as high molecular mass aggregates or in outer membrane vesicles

scientific article published in January 2017

High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses

scientific article published on 19 December 2011

Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes.

scientific article

Human bactericidal/permeability-increasing protein and a recombinant NH2-terminal fragment cause killing of serum-resistant gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria ⬇️

scientific article published on September 1, 1992

IFN-α and lipopolysaccharide upregulate APOBEC3 mRNA through different signaling pathways.

scientific article

Identification of single nucleotide polymorphisms in hematopoietic cell transplant patients affecting early recognition of, and response to, endotoxin

scientific article published on 9 October 2013

Introduction: Forum in immunology on neutrophils

scientific article published on November 2003

Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations

scholarly article

Isolation of monomeric and dimeric secreted MD-2. Endotoxin.sCD14 and Toll-like receptor 4 ectodomain selectively react with the monomeric form of secreted MD-2.

scientific article published on 2 June 2008

Killing of gram-negative bacteria by polymorphonuclear leukocytes: role of an O2-independent bactericidal system.

scientific article published on April 1982

LBP/BPI proteins and their relatives: conservation over evolution and roles in mutualism

scientific article (publication date: August 2011)

Lipopolysaccharide (LPS)-binding proteins BPI and LBP form different types of complexes with LPS.

scientific article published in July 1997

Lipopolysaccharide deacylation by an endogenous lipase controls innate antibody responses to Gram-negative bacteria.

scientific article

Low concentrations of indomethacin inhibit phospholipase A2 of rabbit polymorphonuclear leukocytes ⬇️

scientific article published on June 1, 1978

MD-2-dependent pulmonary immune responses to inhaled lipooligosaccharides: effect of acylation state

scientific article published on 18 January 2008

Metabolic labeling to characterize the overall composition of Francisella lipid A and LPS grown in broth and in human phagocytes.

scientific article published on 31 May 2013

Mobilization of potent plasma bactericidal activity during systemic bacterial challenge. Role of group IIA phospholipase A2 ⬇️

scientific article published on August 1, 1998

Modification of sample processing for the Limulus amebocyte lysate assay enhances detection of inflammogenic endotoxin in intact bacteria and organic dust

scientific article published in January 2017

Molecular Basis of the Functional Differences between Soluble Human Versus Murine MD-2: Role of Val135 in Transfer of Lipopolysaccharide from CD14 to MD-2.

scientific article published on 29 January 2016

Molecular basis of reduced potency of underacylated endotoxins

scientific article

Molecular determinants of bacterial sensitivity and resistance to mammalian Group IIA phospholipase A2.

scientific article published on 12 June 2015

NMR studies of hexaacylated endotoxin bound to wild-type and F126A mutant MD-2 and MD-2·TLR4 ectodomain complexes

scientific article

Neutrophil bleaching of GFP-expressing staphylococci: probing the intraphagosomal fate of individual bacteria

scientific article

Neutrophil elastase targets virulence factors of enterobacteria

scientific article (publication date: 2 May 2002)

Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly ⬇️

scientific article published on January 15, 1998

Novel roles in human MD-2 of phenylalanines 121 and 126 and tyrosine 131 in activation of Toll-like receptor 4 by endotoxin

scientific article published on 30 October 2007

Novel roles of lysines 122, 125, and 58 in functional differences between human and murine MD-2.

scientific article

OmpR-dependent and OmpR-independent responses of Escherichia coli to sublethal attack by the neutrophil bactericidal/permeability increasing protein.

scientific article published in March 2002

Organism-specific neutrophil-endothelial cell interactions in response to Escherichia coli, Streptococcus pneumoniae, and Staphylococcus aureus

scientific article published on January 2004

Partial characterization and purification of a rabbit granulocyte factor that increases permeability of Escherichia coli ⬇️

scientific article published on January 1, 1975

Phospholipase A activity associated with membranes of human polymorphonuclear leucocytes

scientific article published on December 1, 1977

Phospholipase A2 activity in the plasma membrane of human polymorphonuclear leukocytes

scientific article published on 01 December 1981

Phospholipid synthesis by Staphylococcus aureus during (Sub)Lethal attack by mammalian 14-kilodalton group IIA phospholipase A2.

scientific article published on March 2000

Polymyxin B-Resistant Acinetobacter baumannii Clinical Isolate Susceptible to Recombinant BPI and Cecropin P1.

scientific article published on March 2001

Potent bactericidal activity towards gram-positive bacteria of mammalian group II phospholipase A2 mobilized in inflammatory fluids

scientific article published on 01 October 1996

Purified monomeric ligand.MD-2 complexes reveal molecular and structural requirements for activation and antagonism of TLR4 by Gram-negative bacterial endotoxins

scientific article

Radioiodination of an endotoxin·MD-2 complex generates a novel sensitive, high-affinity ligand for TLR4.

scientific article published on 25 February 2013

Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells

scientific article published on January 2007

Regulation of interactions of endotoxin with host cells.

scientific article published on January 2003

Relation between binding and the action of phospholipases A2 on Escherichia coli exposed to the bactericidal/permeability-increasing protein of neutrophils

scientific article published on 01 August 1987

Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.

scientific article

Reversible envelope effects during and after killing of Escherichia coli w by a highly-purified rabbit polymorpho-nuclear leukocyte fraction

scientific article published on 01 June 1976

Role of charge properties of bacterial envelope in bactericidal action of human group IIA phospholipase A2 against Staphylococcus aureus

scientific article published on 30 September 2002

Role of the bactericidal/permeability-increasing protein in host defence.

scientific article published on February 1998

Specific high affinity interactions of monomeric endotoxin.protein complexes with Toll-like receptor 4 ectodomain

scientific article published on 22 November 2006

Stable isotope metabolic labeling of Neisseria meningitidis lipooligosaccharide

scientific article published in January 2006

Structural and functional features of a developmentally regulated lipopolysaccharide-binding protein

scientific article

Structural and functional organization of the human neutrophil 60 kDa bactericidal/permeability-increasing protein ⬇️

scientific article published on September 1, 1991

Synergy between extracellular group IIA phospholipase A2 and phagocyte NADPH oxidase in digestion of phospholipids of Staphylococcus aureus ingested by human neutrophils.

scientific article

Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions

scientific article published on 13 January 2014

The TLR4 antagonist Eritoran protects mice from lethal influenza infection

scientific article published on May 2013

The bactericidal/permeability-increasing protein (BPI) in infection and inflammatory disease.

scientific article published on 13 July 2007

The bactericidal/permeability-increasing protein (BPI), a potent element in host-defense against gram-negative bacteria and lipopolysaccharide.

scientific article

The carboxyl-terminal domain of closely related endotoxin-binding proteins determines the target of protein-lipopolysaccharide complexes

scientific article (publication date: 8 March 2002)

The cationic amphiphile 3,4-bis(tetradecyloxy)benzylamine inhibits LPS signaling by competing with endotoxin for CD14 binding

scientific article published on 23 June 2010

The mission of the International Endotoxin and Innate Immunity Society

scientific article published in December 2013

The phospholipid-repair system LplT/Aas in Gram-negative bacteria protects the bacterial membrane envelope from host phospholipase A2 attack

scientific article published on 18 January 2018

The potent anti-Staphylococcus aureus activity of a sterile rabbit inflammatory fluid is due to a 14-kD phospholipase A2.

scientific article

The role of complement opsonization in interactions between F. tularensis subsp. novicida and human neutrophils

scientific article published on 04 May 2009

The use of a phospholipase A-less Escherichia coli mutant to establish the action of granulocyte phospholipase A on bacterial phospholipids during killing by a highly purified granulocyte fraction ⬇️

scientific article published on April 1, 1977

Transfer of monomeric endotoxin from MD-2 to CD14: characterization and functional consequences

scientific article

Uniform lipopolysaccharide (LPS)-loaded magnetic nanoparticles for the investigation of LPS-TLR4 signaling.

scientific article published on 9 November 2010

Wall teichoic acid deficiency in Staphylococcus aureus confers selective resistance to mammalian group IIA phospholipase A(2) and human beta-defensin 3

scientific article published on 17 March 2008

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