List of works - Christian Tackenberg

A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain

scientific article published on 20 March 2020

APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes

scientific article

Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice.

scientific article published on 12 June 2012

Alzheimer's in a dish - induced pluripotent stem cell-based disease modeling

scientific article published on 12 July 2019

Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D

scientific article

Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss

scientific article

Characterization of the Blood Brain Barrier Disruption in the Photothrombotic Stroke Model

scientific article published on 12 November 2020

Divergent pathways mediate spine alterations and cell death induced by amyloid-beta, wild-type tau, and R406W tau.

scientific article published in November 2009

Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation

scientific article

Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system

scientific article published on 23 September 2020

Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease.

scientific article published on 19 July 2016

High-resolution imaging and evaluation of spines in organotypic hippocampal slice cultures.

scientific article published in January 2012

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

scientific article published on 25 April 2013

Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients

scientific article published on 26 January 2018

Stem Cell Therapy for Repair of the Injured Brain: Five Principles

scientific article published in 2022

Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices.

scientific article published on May 2006

The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation

scientific article published on 29 March 2019

Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications

scientific article published in 2022

List of works by Christian Tackenberg

A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain

APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes

Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice.

Alzheimer's in a dish - induced pluripotent stem cell-based disease modeling

Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D

Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss

Characterization of the Blood Brain Barrier Disruption in the Photothrombotic Stroke Model

Divergent pathways mediate spine alterations and cell death induced by amyloid-beta, wild-type tau, and R406W tau.

Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation

Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system

Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease.

High-resolution imaging and evaluation of spines in organotypic hippocampal slice cultures.

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients

Stem Cell Therapy for Repair of the Injured Brain: Five Principles

Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices.

The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation

Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications