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List of works by Anne Skaja Robinson

Aggregates of α-chymotrypsinogen anneal to access more stable states

scientific article

Analysis of ER resident proteins in Saccharomyces cerevisiae: implementation of H/KDEL retrieval sequences.

scientific article

Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds.

scientific article published on November 2010

Analysis of unfolded protein response during single-chain antibody expression in Saccaromyces cerevisiae reveals different roles for BiP and PDI in folding.

scientific article published in July 2005

BiP clustering facilitates protein folding in the endoplasmic reticulum

scientific article

C-terminal hydrophobic interactions play a critical role in oligomeric assembly of the P22 tailspike trimer.

scientific article published on December 2003

Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast.

scientific article

Coarse-grained model for colloidal protein interactions, B(22), and protein cluster formation

scientific article

Competing aggregation pathways for monoclonal antibodies

scientific article published on 12 February 2014

Computational design and biophysical characterization of aggregation-resistant point mutations for γD crystallin illustrate a balance of conformational stability and intrinsic aggregation propensity.

scientific article

Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein

scientific article

Conformational stability as a design target to control protein aggregation.

scientific article

Conserved disulfide bond is not essential for the adenosine A2A receptor: Extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition.

scientific article published on 16 November 2014

Controllability analysis of protein glycosylation in CHO cells

scientific article published on 3 February 2014

Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation

scientific article published on 21 December 2017

Decreased Secretion and Unfolded Protein Response Upregulation ⬇️

scientific article published on January 1, 2011

Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae.

scientific article published on September 2002

Decreases in yeast expression yields of the human adenosine A2a receptor are a result of translational or post-translational events.

scientific article

Development of at-line assay to monitor charge variants of MAbs during production

scientific article published on 30 December 2013

Dissociation of intermolecular disulfide bonds in P22 tailspike protein intermediates in the presence of SDS

scientific article

Disulphide-bonded intermediate on the folding and assembly pathway of a non-disulphide bonded protein

scientific article published on 01 June 1997

Elevated expression temperature in a mesophilic host results in increased secretion of a hyperthermophilic enzyme and decreased cell stress.

scientific article published in August 2005

Enhanced insulin-like growth factor-I (IGF-I) cell association at reduced pH is dependent on IGF binding protein-3 (IGFBP-3) interaction.

scientific article published on February 2007

Exceptional total and functional yields of the human adenosine (A2a) receptor expressed in the yeast Saccharomyces cerevisiae.

scientific article

Functional Expression of Adenosine A3 Receptor in Yeast Utilizing a Chimera with the A2AR C-Terminus

scientific article published on 26 June 2020

Heparan Sulfate Proteoglycans (HSPGs) Serve as the Mediator Between Monomeric Tau and Its Subsequent Intracellular ERK1/2 Pathway Activation

scientific article published on 18 January 2022

Identification of manipulated variables for a glycosylation control strategy

scientific article published on 22 May 2014

Identifying a robust design space for glycosylation during monoclonal antibody production

scientific article

Impact of purification conditions and history on A2A adenosine receptor activity: The role of CHAPS and lipids.

scientific article published on 27 May 2016

Media supplementation for targeted manipulation of monoclonal antibody galactosylation and fucosylation

scientific article published on 14 July 2020

Modulating non-native aggregation and electrostatic protein-protein interactions with computationally designed single-point mutations

scientific article

New tools for breaking barriers to GPCR expression in E. coli.

scientific article

P22 tailspike trimer assembly is governed by interchain redox associations.

scientific article

Pressure treatment of tailspike aggregates rapidly produces on-pathway folding intermediates.

scientific article published in June 2003

Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae

scientific article published on 01 April 1994

Protein folding and secretion: mechanistic insights advancing recombinant protein production in S. cerevisiae.

scientific article published on 15 July 2014

Rapid refolding and polishing of single-chain antibodies from Escherichia coli inclusion bodies

scientific article published on 01 November 2002

Recombinant G protein-coupled receptor expression in Saccharomyces cerevisiae for protein characterization.

scientific article published on 20 March 2015

Recombinant protein expression and purification: a comprehensive review of affinity tags and microbial applications

scientific article published on 10 January 2012

Reduction of BiP levels decreases heterologous protein secretion in Saccharomyces cerevisiae.

scientific article

Refolding of G protein alpha subunits from inclusion bodies expressed in Escherichia coli.

scientific article published on 8 December 2007

Role for cysteine residues in the in vivo folding and assembly of the phage P22 tailspike

scientific article

Spatial localisation of chaperone distribution in the endoplasmic reticulum of yeast ⬇️

scientific article published on April 1, 2012

Structure-function studies with G protein-coupled receptors as a paradigm for improving drug discovery and development of therapeutics.

scientific article published on December 2012

The C-terminus of the P22 tailspike protein acts as an independent oligomerization domain for monomeric proteins.

scientific article

The Saccharomyces cerevisiae YFR041C/ERJ5 gene encoding a type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum.

scientific article

The Specificity of Downstream Signaling for A<sub>1</sub> and A<sub>2A</sub>R Does Not Depend on the C-Terminus, Despite the Importance of This Domain in Downstream Signaling Strength

scientific article published on 13 December 2020

The morphology and composition of cholesterol-rich micellar nanostructures determine transmembrane protein (GPCR) activity.

scientific article published on January 2011

Three amino acids that are critical to formation and stability of the P22 tailspike trimer.

scientific article published on 4 August 2005

Toward rational design of protein detergent complexes: determinants of mixed micelles that are critical for the in vitro stabilization of a G-protein coupled receptor.

scientific article

Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology

scientific article

Weak protein interactions and pH- and temperature-dependent aggregation of human Fc1.

scientific article published on 12 August 2015

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