List of works - Istvan Greiner

4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate

scientific article published on 11 January 2016

A Study of the pH Dependence of the Two-Step Oximation of Acetone by in situ Fourier Transform Infrared Spectroscopy

article by György Keglevich et al published March 2008 in Chemical Engineering and Technology

Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists.

scientific article published on 17 June 2010

Charting the chemical space around the (iso)indoline scaffold, a comprehensive approach towards multitarget directed ligands.

scientific article published on 25 July 2016

Continuous Synthesis and Purification by Coupling a Multistep Flow Reaction with Centrifugal Partition Chromatography.

scientific article

Controlling receptor function from the extracellular vestibule of G-protein coupled receptors

scientific article published on 20 October 2020

Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications.

scientific article

Discovery of cariprazine (RGH-188): a novel antipsychotic acting on dopamine D3/D2 receptors.

scientific article

Fragment Based Optimization of Metabotropic Glutamate Receptor 2 (mGluR2) Positive Allosteric Modulators in the Absence of Structural Information

scientific article published on 5 March 2018

Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs

scientific article published on 22 April 2010

Indole-2-carboxamidines as novel NR2B selective NMDA receptor antagonists.

scientific article

Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists

scientific article published on 17 October 2006

New practical synthesis of Tamsulosin.

scientific article

Solid-phase synthesis of an N-(phenylalkyl)cinnamide library via Horner-Wadsworth-Emmons reaction.

scientific article published in March 2004

Synthesis of Hydroxymethylenebisphosphonic Acid Derivatives in Different Solvents

scientific article

Synthesis of vinca alkaloids and related compounds. 100. Stereoselective oxidation reactions of compounds with the aspidospermane and quebrachamine ring system. First synthesis of some alkaloids containing the epoxy ring.

scientific article published in October 2002

Thieno[2,3-b]pyridines as negative allosteric modulators of metabotropic GluR5 receptors: Lead optimization

scientific article published on 7 March 2015

Thieno[2,3-b]pyridines as negative allosteric modulators of metabotropic GluR5 receptors: hit-to-lead optimization.

scientific article

List of works by Istvan Greiner

4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate

A Study of the pH Dependence of the Two-Step Oximation of Acetone by in situ Fourier Transform Infrared Spectroscopy

Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists.

Charting the chemical space around the (iso)indoline scaffold, a comprehensive approach towards multitarget directed ligands.

Continuous Synthesis and Purification by Coupling a Multistep Flow Reaction with Centrifugal Partition Chromatography.

Controlling receptor function from the extracellular vestibule of G-protein coupled receptors

Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications.

Discovery of cariprazine (RGH-188): a novel antipsychotic acting on dopamine D3/D2 receptors.

Fragment Based Optimization of Metabotropic Glutamate Receptor 2 (mGluR2) Positive Allosteric Modulators in the Absence of Structural Information

Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs

Indole-2-carboxamidines as novel NR2B selective NMDA receptor antagonists.

Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists

New practical synthesis of Tamsulosin.

Solid-phase synthesis of an N-(phenylalkyl)cinnamide library via Horner-Wadsworth-Emmons reaction.

Synthesis of Hydroxymethylenebisphosphonic Acid Derivatives in Different Solvents

Synthesis of vinca alkaloids and related compounds. 100. Stereoselective oxidation reactions of compounds with the aspidospermane and quebrachamine ring system. First synthesis of some alkaloids containing the epoxy ring.

Thieno[2,3-b]pyridines as negative allosteric modulators of metabotropic GluR5 receptors: Lead optimization

Thieno[2,3-b]pyridines as negative allosteric modulators of metabotropic GluR5 receptors: hit-to-lead optimization.