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List of works by Nicholas D Huntington

A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma Patients

scientific article published on 14 May 2019

A crucial role for the homeodomain transcription factor Hhex in lymphopoiesis.

scientific article

A new checkpoint for Natural Killer cell activation.

scientific article published on 15 December 2017

A novel mouse model for stable engraftment of a human immune system and human hepatocytes

scientific article

A point mutation in the signal peptide impairs the development of innate lymphoid cell subsets

scientific article published on 15 August 2018

A radio-resistant perforin-expressing lymphoid population controls allogeneic T cell engraftment, activation, and onset of graft-versus-host disease in mice

scientific article published on 12 November 2014

A2AR adenosine signaling suppresses natural killer cell maturation in the tumor microenvironment.

scientific article published on 11 December 2017

Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo.

scientific article published on 31 March 2017

Author Correction: Tissue-resident memory CD8+ T cells promote melanoma-immune equilibrium in skin

scientific article published on 01 February 2019

Bone marrow transplantation generates T cell-dependent control of myeloma in mice

scientific article published on 19 November 2018

CD19 differentially regulates BCR signalling through the recruitment of PI3K.

scientific article published on 23 June 2014

CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers

scientific article published on 25 December 2005

CIS is a potent checkpoint in NK cell-mediated tumor immunity

scientific article

Characterization of the thymic IL-7 niche in vivo.

scholarly article

Complementarity and redundancy of IL-22-producing innate lymphoid cells.

scientific article

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection

scientific article published on 01 August 2019

Cord Blood CD8+ T Cells Have a Natural Propensity to Express IL-4 in a Fatty Acid Metabolism and Caspase Activation-Dependent Manner.

scientific article published on 25 April 2018

Cutting Edge: a thymocyte-thymic epithelial cell cross-talk dynamically regulates intrathymic IL-7 expression in vivo.

scientific article published on 3 May 2010

DNAM-1 expression marks an alternative program of NK cell maturation.

scientific article published on 26 March 2015

DNAM-1: would the real natural killer cell please stand up!

scientific article published on October 2015

Development, Homeostasis, and Heterogeneity of NK Cells and ILC1.

scientific article published on 26 August 2015

Differential requirement for Nfil3 during NK cell development.

scientific article

ER stress triggers apoptosis by activating BH3-only protein Bim

scientific article (publication date: 29 June 2007)

GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function

scientific article published on 28 August 2018

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.

scientific article published on 07 December 2016

Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice

scientific article (publication date: 4 October 2010)

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells

scientific article published on 23 August 2018

Granzyme M has a critical role in providing innate immune protection in ulcerative colitis

scientific article published on 21 July 2016

Human RORγt(+)CD34(+) cells are lineage-specified progenitors of group 3 RORγt(+) innate lymphoid cells.

scientific article published on 28 November 2014

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

scientific article published on July 2009

IL-15 signaling in NK cell cancer immunotherapy.

scientific article published on 8 November 2016

IL-15 transpresentation promotes both human T-cell reconstitution and T-cell–dependent antibody responses in vivo ⬇️

scientific article published on March 28, 2011

IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.

scientific article published on 21 June 2019

IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos

scientific article published on 18 September 2018

Identification of Novel Human NK Cell Progenitor Subsets.

scientific article published on 15 December 2017

Immune homeostasis in health and disease

scientific article published on 01 May 2018

Impact of Tumor and Immunological Heterogeneity on the Anti-Cancer Immune Response

scientific article published on 21 August 2019

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

scientific article published in Nature

Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells.

scientific article published on 29 July 2016

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells.

scientific article published on 14 August 2014

Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells.

scientific article

Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.

scientific article

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7.

scientific article published on 19 May 2009

Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β

scientific article published on 01 May 2019

Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.

scientific article

MAIT cells regulate NK cell-mediated tumor immunity

scientific article published on 06 August 2021

Molecular insight into targeting the NK cell immune response to cancer

scientific article published on 17 April 2018

NK cell recognition of unconventional ligands.

scientific article published in March 2014

Nfil3 is required for the development of all innate lymphoid cell subsets.

scientific article

PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors.

scientific article published on 11 June 2018

Quantifying NK cell growth and survival changes in response to cytokines and regulatory checkpoint blockade helps identify optimal culture and expansion conditions

scientific article published on 12 May 2019

Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection‡.

scientific article published on 12 January 2018

Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes

scientific article published on 12 November 2018

Regulation of Murine Natural Killer Cell Development.

scientific article published on 15 February 2017

Regulation of murine natural killer cell commitment

scientific article published on 30 January 2013

Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling

scientific article published on 14 February 2017

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

scientific article

Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis.

scientific article published on 26 June 2017

Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis.

scientific article published on 7 February 2017

Targeting natural killer cells in cancer immunotherapy

scientific article published on August 2016

The Antitumor Effect of Heparin is not Mediated by Direct NK Cell Activation

scientific article published on 18 August 2020

The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy

scientific article published on 10 January 2019

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

scientific article published on 9 January 2016

The cancer-natural killer cell immunity cycle

scientific article published on 24 June 2020

The life and death of immune cell types: the role of BCL-2 anti-apoptotic molecules.

scientific article

The unconventional expression of IL-15 and its role in NK cell homeostasis

scientific article published on 04 February 2014

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

scientific article published on 27 August 2019

Thymic epithelial cells: the multi-tasking framework of the T cell "cradle".

scientific article published on 24 September 2009

Tissue-resident memory CD8+ T cells promote melanoma-immune equilibrium in skin

scientific article published on 31 December 2018

Transforming growth factor-β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells.

scientific article published on 3 May 2016

Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells.

scientific article

Type 1 Innate Lymphoid Cell Biology: Lessons Learnt from Natural Killer Cells

scientific article

You Have Got a Fast CAR: Chimeric Antigen Receptor NK Cells in Cancer Therapy

scientific article published on 17 March 2020

miR17~92 restrains pro-apoptotic BIM to ensure survival of haematopoietic stem and progenitor cells

scientific article published on 07 October 2019

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