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List of works by Lisa M Butler

A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response

scientific article published on 16 August 2016

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

scientific article published on 6 June 2016

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

scientific article published in 2021

A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease

scientific article published on 24 January 2012

A patient-derived explant (PDE) model of hormone-dependent cancer

scientific article published on 16 August 2018

Altered endosome biogenesis in prostate cancer has biomarker potential

scientific article published on 30 July 2014

An Analysis of a Multiple Biomarker Panel to Better Predict Prostate Cancer Metastasis After Radical Prostatectomy

scientific article published on 04 December 2018

An androgen receptor mutation in the MDA-MB-453 cell line model of molecular apocrine breast cancer compromises receptor activity

scientific article

Androgen control of lipid metabolism in prostate cancer: novel insights and future applications

scientific article

Antiproliferative actions of the synthetic androgen, mibolerone, in breast cancer cells are mediated by both androgen and progesterone receptors.

scientific article published on 20 April 2008

Assessment of Periprostatic and Subcutaneous Adipose Tissue Lipolysis and Adipocyte Size from Men with Localized Prostate Cancer

scientific article published on 28 May 2020

Bringing androgens up a NOTCH in breast cancer

scientific article published on 07 July 2014

Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers.

scientific article

Circulating microRNAs: macro-utility as markers of prostate cancer?

scientific article

Co-targeting AR and HSP90 suppresses prostate cancer cell growth and prevents resistance mechanisms

scientific article published on 17 July 2015

Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors.

scientific article published on May 2013

Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.

scientific article published in June 2011

Differential effects of exogenous androgen and an androgen receptor antagonist in the peri- and postpubertal murine mammary gland.

scientific article published on 16 August 2011

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

scientific article published in 2022

Dual roles of PARP-1 promote cancer growth and progression

scientific article published on 19 September 2012

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion

scientific article published in February 2018

Effect of FAK inhibitor VS-6063 (defactinib) on docetaxel efficacy in prostate cancer.

scientific article

Endosomal gene expression: a new indicator for prostate cancer patient prognosis?

scientific article published on 14 October 2015

Erratum to: IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor

scientific article published on 3 March 2016

Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry

scientific article published on 18 October 2019

Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors

scientific article

Ex vivo culture of human prostate tissue and drug development

scientific article published on 11 June 2013

Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer

scientific article published on 15 January 2019

Fatty acid oxidation is an adaptive survival pathway induced in prostate tumors by heat shock protein 90 inhibition

scientific article published on 15 July 2020

Finding the place of histone deacetylase inhibitors in prostate cancer therapy.

scientific article

GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells

scientific article

Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development

scientific article

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells.

scientific article published on 7 June 2016

Hsp90: Still a viable target in prostate cancer ⬇️

scientific article published on December 31, 2012

Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis

scientific article published on 20 July 2020

Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein

scientific article published on 30 January 2018

Human seminal fluid as a source of prostate cancer-specific microRNA biomarkers

article

Identification of novel response and predictive biomarkers to Hsp90 inhibitors through mass spectrometry-based proteomic profiling of patient-derived prostate tumor explants

scientific article published on 9 April 2018

Identification of prostate cancer-associated microRNAs in circulation using a mouse model of disease.

scientific article published in January 2013

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

article published in the Proceedings of the National Academy of Sciences of the United States of America

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

scientific article published on 6 July 2013

Maximizing the Therapeutic Potential of HSP90 Inhibitors

scientific article (publication date: November 2015)

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2.

scientific article published on 23 December 2016

Molecular and structural basis of androgen receptor responses to dihydrotestosterone, medroxyprogesterone acetate and Δ(4)-tibolone.

scientific article published on 14 November 2013

Molecular pathology and prostate cancer therapeutics: from biology to bedside

scientific article published on January 2014

Multiple nuclear receptor signaling pathways mediate the actions of synthetic progestins in target cells ⬇️

scientific article published on September 16, 2011

New Opportunities for Targeting the Androgen Receptor in Prostate Cancer.

scientific article published on 12 March 2018

Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats

scientific article published on 17 August 2018

Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

scientific article published on 06 June 2018

Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer

scientific article

Peri-Prostatic Adipose Tissue: The metabolic microenvironment of prostate cancer.

scientific article published on 20 February 2018

Precision nanomedicines for prostate cancer

scientific article published on 27 February 2018

Prostate cell lines as models for biomarker discovery: performance of current markers and the search for new biomarkers

scientific article published on 16 January 2014

Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis

scientific article published on 13 March 2020

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription.

scientific article

Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client

scholarly article by Andrew P Trotta published in June 2012

Targeting cell cycle and hormone receptor pathways in cancer.

scientific article published on 27 May 2013

The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer

scientific article published on 11 August 2017

The Magnitude of Androgen Receptor Positivity in Breast Cancer Is Critical for Reliable Prediction of Disease Outcome

scientific article published on 7 March 2018

The dynamic and static modification of the epigenome by hormones: a role in the developmental origin of hormone related cancers.

scientific article published on 02 January 2009

The inverse relationship between prostate specific antigen (PSA) and obesity

scientific article published in November 2018

Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors.

scientific article

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