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List of works by Margaret M Centenera

A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response

scientific article published on 16 August 2016

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

scientific article published on 6 June 2016

A patient-derived explant (PDE) model of hormone-dependent cancer

scientific article published on 16 August 2018

Androgen control of lipid metabolism in prostate cancer: novel insights and future applications

scientific article

Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer

scientific article

Co-targeting AR and HSP90 suppresses prostate cancer cell growth and prevents resistance mechanisms

scientific article published on 17 July 2015

Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors.

scientific article published on May 2013

Dual roles of PARP-1 promote cancer growth and progression

scientific article published on 19 September 2012

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion

scientific article published in February 2018

Effect of FAK inhibitor VS-6063 (defactinib) on docetaxel efficacy in prostate cancer.

scientific article

Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors.

scientific article

Ex vivo culture of human prostate tissue and drug development

scientific article published on 11 June 2013

Finding the place of histone deacetylase inhibitors in prostate cancer therapy.

scientific article

GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells

scientific article

Identification of novel response and predictive biomarkers to Hsp90 inhibitors through mass spectrometry-based proteomic profiling of patient-derived prostate tumor explants

scientific article published on 9 April 2018

Insights from AR Gene Mutations

article

Maximizing the Therapeutic Potential of HSP90 Inhibitors

scientific article (publication date: November 2015)

Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

scientific article published on 06 June 2018

Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer

scientific article

Suppression of androgen receptor signaling in prostate cancer cells by an inhibitory receptor variant.

scientific article published on 19 January 2006

Targeting cell cycle and hormone receptor pathways in cancer.

scientific article published on 27 May 2013

The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer

scientific article published on 11 August 2017

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