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List of works by Janusz A Siedlecki

AMP-activated protein kinase (AMPK) as therapeutic target

scientific article

Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas

scientific article published on 10 September 2016

Active transport of RB protein from the nucleus to the cytoplasm as one of the development mechanisms of HER2-positive breast cancer.

scientific article published in April 2013

Advanced adenoid cystic carcinoma (ACC) is featured by SWI/SNF chromatin remodeling complex aberrations

scientific article published on 31 October 2018

Alternative forms of beta-pol mRNA are not tumor-specific and are not the result of mutations in the DNA

scientific article published on 01 February 2000

Alternative splicing of DNA polymerase beta mRNA is not tumor-specific

scientific article published on 01 October 1996

Association of the BRCA1 promoter polymorphism rs11655505 with the risk of familial breast and/or ovarian cancer

scientific article published in December 2013

BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex-a tumour suppressor or tumour-promoting factor?

scientific article

Cardiotoxicity danger in immunotherapy

scientific article published on 02 May 2020

Cell-free DNA BRAF V600E measurements during BRAF inhibitor therapy of metastatic melanoma: long-term analysis

scientific article published on 06 February 2020

Changes in the DNA polymerase beta gene expression during development of lung, brain, and testis suggest an involvement of the enzyme in DNA recombination.

scientific article

Characterization of a prokaryotic topoisomerase I activity in chloroplast extracts from spinach

scientific article

Chloroplast DNA synthesis in light and dark grown cultured Nicotiana tabacum cells as determined by molecular hybridization

scientific article published on 01 April 1985

Clinical utility of the new American Joint Committee on Cancer staging system for gastrointestinal stromal tumors: current overall survival after primary tumor resection

scientific article

Comparison between two widely used laboratory methods in BRAF V600 mutation detection in a large cohort of clinical samples of cutaneous melanoma metastases to the lymph nodes.

scientific article

Comparison of promoter DNA methylation and expression levels of genes encoding CCAAT/enhancer binding proteins in AML patients

scientific article published on 09 May 2014

DNA Methylation Influences miRNA Expression in Gonadotroph Pituitary Tumors

scientific article published on 13 May 2020

DNA methylation profiling in nonfunctioning pituitary adenomas.

scientific article published on 31 January 2018

Decreased repair activities of 1,N(6)-ethenoadenine and 3,N(4)-ethenocytosine in lung adenocarcinoma patients.

scientific article published in August 2003

Detection of carbonic anhydrase 9-expressing tumor cells in the lymph nodes of vulvar carcinoma patients by RT-PCR.

scientific article

Detection of circulating breast cancer cells in peripheral blood by a two-marker reverse transcriptase-polymerase chain reaction assay.

scientific article published on January 2004

Detection of circulating melanoma cells in peripheral blood by a two-marker RT-PCR assay

scientific article published on 01 February 2001

Detection of melanoma cells in the lymphatic drainage after lymph node dissection in melanoma patients by using two-marker reverse transcriptase-polymerase chain reaction assay.

scientific article published on 15 October 2004

Developments in targeted therapy of advanced gastrointestinal stromal tumors.

scientific article published on June 2008

Different factors are responsible for predicting relapses after primary tumors resection and for imatinib treatment outcomes in gastrointestinal stromal tumors

scientific article published in November 2007

Downregulation of PTPRH (Sap-1) in colorectal tumors.

scientific article published on 5 July 2017

Downstream and intermediate interactions of synovial sarcoma-associated fusion oncoproteins and their implication for targeted therapy

scientific article published on 25 March 2012

EGFR, PIK3CA, KRAS and BRAF mutations in meningiomas

scientific article

Effect of busulphan treatment and elevated temperature on the expression of the beta-pol gene in rat testis

scientific article published on 01 February 1991

Effects of BRCA Germline Mutations on Triple-Negative Breast Cancer Prognosis

scientific article published on 27 January 2020

Evaluation of prognostic significance of circulating tumor cells detection in rectal cancer patients treated with preoperative radiotherapy: prospectively collected material data.

scientific article

Evaluation of the role of downregulation of SNF5/INI1 core subunit of SWI/SNF complex in clear cell renal cell carcinoma development

scientific article published in November 2017

Evidence implying DNA polymerase β function in excision repair ⬇️

scientific article published on January 25, 1980

Expression changes of cell-cell adhesion-related genes in colorectal tumors.

scientific article published on 8 April 2015

Fapyadenine is a moderately efficient chain terminator for prokaryotic DNA polymerases

scientific article published on 01 January 2000

FcγRIIA and FcγRIIIA polymorphisms do not influence survival and response to rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone immunochemotherapy in patients with diffuse large B-cell lymphoma

scientific article published on 10 June 2011

Gene expression profiling of peripheral blood cells: new insights into Ewing sarcoma biology and clinical applications

scientific article

HAX-1 is a nucleocytoplasmic shuttling protein with a possible role in mRNA processing.

scientific article

HAX-1 overexpression, splicing and cellular localization in tumors

scientific article

Hairpin structure within the 3'UTR of DNA polymerase beta mRNA acts as a post-transcriptional regulatory element and interacts with Hax-1

scientific article

Identification and expression analysis of alternative splice variants of the rat Hax-1 gene

scientific article published on 03 March 2006

Inhibition of calf thymus DNA polymerase alpha and of normal and cancer cell growth by butylanilinouracil and butylphenylguanine.

scientific article published on October 1982

Lack of microsatellite instability in squamous cell vulvar carcinoma.

scientific article published on 19 January 2012

Levels and size complexity of DNA polymerase beta mRNA in rat regenerating liver and other organs.

scientific article published on July 1989

Long-term follow-up of patients with GIST undergoing metastasectomy in the era of imatinib -- analysis of prognostic factors (EORTC-STBSG collaborative study).

scientific article published on 15 January 2014

Low expression of DNA polymerase beta in human testicular germ cell tumours--impact on foetal gonocytic origin theory

scientific article published on 01 January 2002

Macrophage infiltration and genetic landscape of undifferentiated uterine sarcomas

scientific article

Metastatic potential is determined early in synovial sarcoma development and reflected by tumor molecular features

scientific article published on 16 May 2014

Methyl-CpG binding column-based identification of nine genes hypermethylated in colorectal cancer

scientific article

Molecular alterations in clinical stage III cutaneous melanoma: Correlation with clinicopathological features and patient outcome.

scientific article

Molecular and biochemical testing in stage III melanoma: multimarker reverse transcriptase-polymerase chain reaction assay of lymph fluid after lymph node dissection and preoperative serum lactate dehydrogenase level.

scientific article published on 4 July 2008

Molecular characterization and patient outcome of melanoma nodal metastases and an unknown primary site.

scientific article

Molecular staging by multimarker reverse transcriptase-polymerase chain reaction assay of lymphatic drainage and blood from melanoma patients after lymph node dissection

scientific article published on 01 August 2008

Multimarker reverse transcriptase-polymerase chain reaction assay in lymphatic drainage and sentinel node tumor burden

scientific article

Multiple RT-PCR tyrosinase testing reveals that melanoma cells circulate in the blood of melanoma patients at the frequency more than 10 times below the detection threshold

scientific article published on 01 August 2002

Mutational Analysis of Recurrent Meningioma Progressing From Atypical to Rhabdoid Subtype.

scientific article published on 15 October 2016

Myocardial Expression of PPARγ and Exercise Capacity in Patients after Coronary Artery Bypass Surgery.

scientific article published on 28 September 2017

PIN1 gene variants in Alzheimer's disease

scientific article published on 12 November 2009

PPAR Gamma Expression Levels during Development of Heart Failure in Patients with Coronary Artery Disease after Coronary Artery Bypass-Grafting.

scientific article

PPARG2 Pro12Ala and TNFα -308G>A Polymorphisms Are Not Associated with Heart Failure Development in Patients with Ischemic Heart Disease after Coronary Artery Bypass Grafting

scientific article published on 02 June 2019

Polymorphisms of DNA repair and oxidative stress genes in B-cell lymphoma patients

scientific article published on 25 October 2012

Predictive factors for long-term effects of imatinib therapy in patients with inoperable/metastatic CD117(+) gastrointestinal stromal tumors (GISTs)

scientific article published on 26 April 2007

Preliminary results of the use of MRD test among children with acute lymphoblastic leukaemia

scientific article published in January 2004

Presence of homozygous KIT exon 11 mutations is strongly associated with malignant clinical behavior in gastrointestinal stromal tumors

scientific article published on 16 July 2007

Prognostic value of IDH1 mutations identified with PCR-RFLP assay in glioblastoma patients

scientific article published in June 2010

Prognostic value of KIT/PDGFRA mutations in gastrointestinal stromal tumours (GIST): Polish Clinical GIST Registry experience

scientific article published on 28 April 2011

Prognostic value of multiple reverse transcription-PCR tyrosinase testing for circulating neoplastic cells in malignant melanoma.

scientific article

Promoter DNA methylation and expression levels of HOXA4, HOXA5 and MEIS1 in acute myeloid leukemia.

scientific article published on 13 January 2015

Promoter methylation and expression levels of selected hematopoietic genes in pediatric B-cell acute lymphoblastic leukemia.

scientific article

Reactions of calf thymus DNA polymerases alpha and beta with native DNA damaged by thymine starvation or by methyl methanesulphonate treatment with Escherichia coli cells

scientific article published on 01 March 1981

Recurrent and novel SS18-SSX fusion transcripts in synovial sarcoma: description of three new cases

scientific article

Regulatory functions of 3'UTRs.

scientific article

Repetitive genomic elements and overall DNA methylation changes in acute myeloid and childhood B-cell lymphoblastic leukemia patients

scientific article published on 20 May 2014

Risk Criteria and Prognostic Factors for Predicting Recurrences After Resection of Primary Gastrointestinal Stromal Tumor

scientific article published on 02 May 2007

Role of Vitamin D and Its Receptors in the Pathophysiology of Chronic Rhinosinusitis

scientific article published on 02 November 2018

SWI/SNF chromatin remodeling complex and glucose metabolism are deregulated in advanced bladder cancer

scientific article published on 19 February 2020

TET2 Promoter DNA Methylation and Expression Analysis in Pediatric B-cell Acute Lymphoblastic Leukemia.

scientific article published on January 2014

The Outcome of Targeted Therapy in Advanced Gastrointestinal Stromal Tumors (Gist) with Non-Exon 11 Kit Mutations

scientific article published on 01 July 2014

The Role of Aberrant DNA Methylation in Misregulation of Gene Expression in Gonadotroph Nonfunctioning Pituitary Tumors

scientific article published on 25 October 2019

The Role of SWI/SNF Chromatin Remodeling Complexes in Hormone Crosstalk

scientific article published on 17 February 2016

The Search of miRNA Related to Invasive Growth of Nonfunctioning Gonadotropic Pituitary Tumors

scientific article published on 05 December 2020

The accuracy of the sentinel lymph node concept in early stage squamous cell vulvar carcinoma.

scientific article published on 17 November 2009

The expression of bitter taste receptor TAS2R38 in patients with chronic rhinosinusitis

scientific article published on 10 September 2020

The frequency of human papillomavirus infection in polish patients with vulvar squamous cell carcinoma.

scientific article published in April 2010

The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study

scientific article

The prognostic role of BRAF and WNT pathways activation in kinase inhibitors-naïve clinical stage III cutaneous melanoma

scientific article published on 17 February 2020

Tumor genotype is an independent prognostic factor in primary gastrointestinal stromal tumors of gastric origin: a european multicenter analysis based on ConticaGIST.

scientific article published on 7 October 2014

USP8 mutations in corticotroph adenomas determine a distinct gene expression profile irrespective of functional tumour status

scientific article published on 01 December 2019

Usefulness of real-time PCR in long-term follow-up of follicular lymphoma patients

scientific article published on 09 March 2007

Various forms of HIF-1α protein characterize the clear cell renal cell carcinoma cell lines

scientific article published on 06 April 2020

What are the current outcomes of advanced gastrointestinal stromal tumors: who are the long-term survivors treated initially with imatinib?

scientific article

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