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List of works by Konstantinos Kostikas

"Education is the passport to the future": enabling today's medical teachers to prepare tomorrow's respiratory health practitioners

scientific article published in September 2014

25-hydroxyvitamin D in malignant pleural disease: a prospective cohort study.

scientific article published on 9 August 2016

A European Respiratory Society technical standard: exhaled biomarkers in lung disease.

scientific article

A Real-World Observational Study Examining the Impact of Aclidinium Bromide Therapy on the Quality of Life, Symptoms, and Activity Impairment of Patients with Chronic Obstructive Pulmonary Disease: The Greek ON-AIR Study

scientific article published on 06 March 2020

Activin A and follistatin in patients with asthma. Does severity make the difference?

scientific article published on 2 November 2016

Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function

scientific article published on February 2013

Adequacy of Therapy for People with Both COPD and Heart Failure in the UK: Historical Cohort Study

scientific article published on 02 June 2020

Adrenomedullin optimises mortality prediction in COPD patients

scientific article published on 6 March 2015

Airway and systemic eosinophilia in asthma: does site matter?

scientific article published in July 2014

Alveolar adenoma: an extremely rare innocent coin lesion ⬇️

scientific article published on December 7, 2011

Associations between BODE Index and Systemic Inflammatory Biomarkers in COPD ⬇️

scientific article published on 01 December 2011

Asthma-chronic obstructive pulmonary disease overlap: Diagnostic stability and inflammatory characteristics

scientific article published on 28 May 2019

At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease.

scientific article

Autoimmunity and Chronic Obstructive Pulmonary Disease: Thinking beyond Cigarette Smoke ⬇️

scientific article published on 01 June 2012

Bilious pericardial effusion at initial presentation in a patient with lung cancer ⬇️

scientific article published on November 8, 2003

Blood eosinophils as biomarkers to drive treatment choices in asthma and COPD.

scientific article published on 12 February 2018

Body Composition in Severe Refractory Asthma: Comparison with COPD Patients and Healthy Smokers ⬇️

scientific article published on October 6, 2010

Bronchoscopic diagnosis and treatment of endobronchial carcinoid: case report and review of the literature

scientific article published on 06 January 2021

Capturing Exacerbations of Chronic Obstructive Pulmonary Disease with EXACT: A Sub-Analysis of FLAME

scientific article published on 01 January 2019

Changes in BODE Quartiles After Pulmonary Rehabilitation Do Not Predict 2-Year Survival in Patients With COPD.

scientific article

Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database

scientific article published on 16 July 2020

Clinical, functional and inflammatory characteristics in patients with paucigranulocytic stable asthma: Comparison with different sputum phenotypes.

scientific article published on 13 April 2017

Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease

scientific article published on 30 June 2018

Collateral damage: depressive symptoms in the partners of COPD patients.

scientific article published on 11 May 2014

Combined pulmonary fibrosis and emphysema: The many aspects of a cohabitation contract.

scientific article

Comparison of a network of primary care physicians and an open spirometry programme for COPD diagnosis ⬇️

scientific article published on 01 February 2011

Diagnostic accuracy of T2 biomarkers for the prediction of airway eosinophilia in treated smoking asthmatic patients with loss of asthma control

scientific article published on 13 June 2019

Differences in COPD Exacerbation Risk Between Women and Men: Analysis From the UK Clinical Practice Research Datalink Data

scientific article published on 16 May 2019

Does the Term "Deflators" Reflect More Accurately the Beneficial Effects of Long-acting Bronchodilators in COPD?

scientific article published on 26 April 2016

Dual Bronchodilation Response by Exacerbation History and Eosinophilia in the FLAME Study.

scientific article published on 3 November 2017

Dual bronchodilation vs triple therapy in the "real-life" COPD DACCORD study

scientific article published on 24 August 2018

Duration of Hospitalization and Lung Function Deterioration as Predictors of Future Chronic Obstructive Pulmonary Disease Exacerbations

scientific article

Early Changes in eDiary COPD Symptoms Predict Clinically Relevant Treatment Response at 12 Weeks: Analysis from the CRYSTAL Study

scientific article published on 16 April 2018

Early Clinically Important Improvement (ECII) and Exacerbation Outcomes in COPD Patients

scientific article published on 28 July 2020

Early bronchodilator action of glycopyrronium versus tiotropium in moderate-to-severe COPD patients: a cross-over blinded randomized study (Symptoms and Pulmonary function in the moRnING)

scientific article published on 28 June 2016

Editorial (Hot Topic: COPD Management Beyond Bronchodilation: Current Targets and Future Prospects) ⬇️

scientific article published on February 1, 2013

Effective sleep apnoea treatment improves cardiac function in patients with chronic heart failure ⬇️

scientific article published on October 2, 2012

Efficacy and safety of direct switch to indacaterol/glycopyrronium in patients with moderate COPD: the CRYSTAL open-label randomised trial

scientific article

Efficacy and safety of the direct switch to indacaterol/glycopyrronium from salmeterol/fluticasone in non-frequently exacerbating COPD patients: The FLASH randomized controlled trial

scientific article published on 03 August 2018

Emphysematous Phenotype is Characterized by Low Blood Eosinophils: A Cross-Sectional Study.

scientific article published on 3 November 2017

Erratum: Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database [Corrigendum]

scientific article published on 16 October 2020

Evaluation of exacerbations and blood eosinophils in UK and US COPD populations

scientific article published on 07 August 2019

Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study.

scientific article

Exertional hypoxemia in stable COPD is common and predicted by circulating proadrenomedullin.

scientific article published in August 2014

Exhaled Nitric Oxide in Asthma in Adults: The End is the Beginning? ⬇️

scientific article published on January 1, 2011

Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers ⬇️

scientific article published on May 22, 2011

Exhaled breath temperature in optimally treated asthmatics: severity and underlying mechanisms

scientific article published on 27 November 2017

Exposure to secondhand smoke promotes sympathetic activity and cardiac muscle cachexia

scientific article published on 26 June 2013

Fetuin-A is Associated with Disease Severity and Exacerbation Frequency in Patients with COPD ⬇️

scientific article published on December 28, 2012

Home-based maintenance tele-rehabilitation reduces the risk for acute exacerbations of COPD, hospitalisations and emergency department visits

scientific article published on 25 May 2017

How Do Dual Long-Acting Bronchodilators Prevent Exacerbations of Chronic Obstructive Pulmonary Disease?

scientific article published on 6 December 2016

IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes.

scientific article published on 21 March 2018

Impact of COPD diagnosis timing on clinical and economic outcomes: the ARCTIC observational cohort study

scientific article published on 13 May 2019

Increased levels of angiopoietins 1 and 2 in sputum supernatant in severe refractory asthma ⬇️

scientific article published on 09 January 2012

Increased levels of osteopontin in sputum supernatant in patients with COPD.

scientific article published in October 2014

Indacaterol and glycopyrronium versus indacaterol on body plethysmography measurements in COPD-a randomised controlled study.

scientific article published on 11 January 2017

Indacaterol/glycopyrronium reduces the risk of clinically important deterioration after direct switch from baseline therapies in patients with moderate COPD: a post hoc analysis of the CRYSTAL study.

scientific article

Indacaterol/glycopyrronium versus salmeterol/fluticasone in the prevention of clinically important deterioration in COPD: results from the FLAME study.

scientific article published on 20 June 2018

Indacaterol/glycopyrronium versus tiotropium or glycopyrronium in long-acting bronchodilator-naïve COPD patients: A pooled analysis

scientific article published on 24 July 2019

Inflammatory profile in optimally treated patients with adult versus early-onset asthma

scientific article published on 04 April 2019

Inhaled corticosteroid use by exacerbations and eosinophils: a real-world COPD population

scientific article published on 16 April 2019

Inhaled corticosteroids in COPD and onset of type 2 diabetes and osteoporosis: matched cohort study

scientific article published on 28 October 2019

Is it prime time to consider a clinical trial of doxycycline for the management of COVID-19?

scientific article published on 03 December 2020

LABA/LAMA combinations versus LAMA monotherapy or LABA/ICS in COPD: a systematic review and meta-analysis.

scientific article

Leptin, Adiponectin, and Ghrelin Levels in Female Patients with Asthma during Stable and Exacerbation Periods ⬇️

scientific article published on December 21, 2012

Letter from Greece

scientific article published on 22 April 2019

Levels of angiopoietins 1 and 2 in induced sputum supernatant in patients with COPD ⬇️

scientific article published on 06 April 2012

Long-Term Triple Therapy De-escalation to Indacaterol/Glycopyrronium in Patients with Chronic Obstructive Pulmonary Disease (SUNSET): A Randomized, Double-Blind, Triple-Dummy Clinical Trial

scientific article published on 01 August 2018

Microbiota and asthma: Clinical implications

scientific article published on 22 November 2018

Mitochondrial genetic background plays a role in increasing risk to asthma ⬇️

scientific article published on September 24, 2011

Noninvasive evaluation of airway inflammation in patients with severe asthma ⬇️

scientific article published on May 1, 2013

Oxidative Stress in Patients with COPD ⬇️

scientific article published on April 1, 2011

Oxidative stress in patients with obstructive sleep apnea syndrome ⬇️

scientific article published on May 18, 2012

Patient Reported Outcomes for the Detection, Quantification and Evaluation of Chronic Obstructive Pulmonary Disease Exacerbations.

scientific article published on 19 April 2018

Patient-Reported Outcomes (PROs) in COPD Clinical Trials: Trends and Gaps

scientific article published on 23 July 2020

Prediction and prevention of exacerbations and mortality in patients with COPD.

scientific article published on 2 May 2016

Prediction of hospitalization stay in COPD exacerbations: the AECOPD-F score.

scientific article published on 24 June 2014

Predictors of future exacerbation risk in patients with asthma.

scientific article published on 5 August 2016

Prevalence and determinants of current and secondhand smoking in Greece: results from the Global Adult Tobacco Survey (GATS) study

scientific article published on 19 January 2017

Prevalence of chronic diseases and morbidity in primary health care in central Greece: An epidemiological study ⬇️

scientific article published on August 28, 2010

Prevalence of lung function impairment among Greek cement production workers: a cross-sectional study

scientific article

Prevalence of sleep-related symptoms in a primary care population - their relation to asthma and COPD.

scientific article published in August 2007

Prognostic assessment in COPD without lung function: the B-AE-D indices.

scientific article

Prostaglandin E2in the expired breath condensate of patients with asthma ⬇️

scientific article published on November 1, 2003

Pulmonary biomarkers in COPD exacerbations: a systematic review

scientific article published on 21 October 2013

Quantitative computed tomography: what does airway obstruction look-like?

scientific article published on September 2016

Real-world retrospective cohort study ARCTIC shows burden of comorbidities in Swedish COPD versus non-COPD patients

scientific article published on 10 September 2018

Reply to: Different Background, Short Duration, Inappropriate Participants May Harm Your Conclusion

scientific article published on 01 February 2019

Respiratory tract mortality in cement workers: a proportionate mortality study ⬇️

scientific article published on June 27, 2012

Response to Indacaterol/Glycopyrronium (IND/GLY) by Sex in Patients with COPD: A Pooled Analysis from the IGNITE Program.

scientific article published on 8 June 2017

Revisiting IL-13 blockade: can we reach the wonderland the inhaled way?

scientific article published on 14 August 2018

Secondhand smoke exposure induces acutely airway acidification and oxidative stress

scientific article published on 04 December 2012

Serum Levels of Surfactant Proteins in Patients with Combined Pulmonary Fibrosis and Emphysema (CPFE)

scientific article

Serum Surfactant Protein Levels in Patients Admitted to the Hospital with Acute COPD Exacerbation

scientific article published on 14 February 2018

Serum angiopoietin-2 and CRP levels during COPD exacerbations.

scientific article published on 8 October 2013

Serum levels of hyaluronic acid are associated with COPD severity and predict survival

scientific article published on 07 March 2019

Serum osteopontin in patients with lung cancer and chronic obstructive pulmonary disease: does the co-existence make the difference?

scientific article published in February 2018

Serum periostin in patients hospitalized for COPD exacerbations.

scientific article published on 13 May 2017

Serum uric acid as a predictor of mortality and future exacerbations of COPD ⬇️

scientific article published on May 3, 2013

Sputum interleukin-13 as a biomarker for the evaluation of asthma control

scientific article published on 15 March 2016

Sputum interleukin-13 as a biomarker for the evaluation of asthma control

scientific article published on 01 November 2016

Stability of the Blood Eosinophilic Phenotype in Stable and Exacerbated COPD.

scientific article published on 29 April 2019

Systemic Biomarkers in the Evaluation and Management of COPD Patients: Are We Getting Closer to Clinical Application? ⬇️

scientific article published on February 1, 2013

Systemic Biomarkers of Collagen and Elastin Turnover Are Associated With Clinically Relevant Outcomes in COPD.

scientific article published on 26 August 2016

Techniques for assessing small airways function: Possible applications in asthma and COPD ⬇️

scientific article published on June 10, 2013

The Association of Metabolic Syndrome with Adipose Tissue Hormones and Insulin Resistance in Patients with COPD without Co-morbidities ⬇️

scientific article published on December 1, 2011

The association between serum periostin and a type 2 helper airway composite index in optimally treated asthmatics.

scientific article published on 7 April 2017

The asthma-COPD overlap syndrome: do we really need another syndrome in the already complex matrix of airway disease?

scientific article

The effect of indacaterol/glycopyrronium versus tiotropium or salmeterol/fluticasone on the prevention of clinically important deterioration in COPD.

scientific article

The epidemiology of pulmonary nontuberculous mycobacteria: data from a general hospital in Athens, Greece, 2007-2013.

scientific article

The role of endosomal toll-like receptors in asthma

scientific article published on 24 September 2016

The role of non-invasive modalities for assessing inflammation in patients with non-cystic fibrosis bronchiectasis.

scientific article published on 29 August 2017

Toward clinically applicable biomarkers for asthma: An EAACI position paper

scientific article published on 01 October 2019

Treatment response to indacaterol/glycopyrronium versus salmeterol/fluticasone in exacerbating COPD patients by gender: a post-hoc analysis in the FLAME study

scientific article published on 08 January 2019

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