Search filters

List of works by Bernard Lagane

A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity.

scientific article

Buffering deleterious polymorphisms in highly constrained parts of HIV-1 envelope by flexible regions

scientific article published on 30 July 2016

CCR5 Mutations Distinguish N-Terminal Modifications of RANTES (CCL5) with Agonist versus Antagonist Activity ⬇️

scientific article published on July 11, 2012

CCR5 adopts three homodimeric conformations that control cell surface delivery.

scientific article

CCR5 structural plasticity shapes HIV-1 phenotypic properties

article

CD4 and CCR5 constitutively interact at the plasma membrane of living cells: a confocal fluorescence resonance energy transfer-based approach

scientific article published on 11 October 2006

CD4 interacts constitutively with multiple CCR5 at the plasma membrane of living cells. A fluorescence recovery after photobleaching at variable radii approach.

scientific article published on 13 September 2007

CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome.

scientific article

CXCR4-tropic HIV-1 envelope glycoprotein functions as a viral chemokine in unstimulated primary CD4+ T lymphocytes

scientific article

CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling.

scientific article published on 20 April 2009

Cholesterol content drives distinct pharmacological behaviours of micro-opioid receptor in different microdomains of the CHO plasma membrane.

scientific article published on August 2008

Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and G(alpha)(i) activation.

scientific article published on 29 December 2006

Dynamic confinement of NK2 receptors in the plasma membrane. Improved FRAP analysis and biological relevance.

scientific article published on 3 August 2004

Guidelines for cloning, expression, purification and functional characterization of primary HIV-1 envelope glycoproteins

scientific article published on 20 July 2016

HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines

scientific article published on 21 May 2013

Lateral distribution of cholesterol in membranes probed by means of a pyrene-labelled cholesterol: effects of acyl chain unsaturation.

scientific article published in January 2002

Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling

scientific article

Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis.

scientific article published on 10 March 2005

New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection

scientific article

Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry.

scientific article

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins

scientific article

Tuberculosis Exacerbates HIV-1 Infection through IL-10/STAT3-Dependent Tunneling Nanotube Formation in Macrophages

scientific article published on 01 March 2019

WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12

scientific article published on 09 November 2004

β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6

scientific article

Paulina is supported by:

About Paulina

Help