List of works - Yoonjoo Choi

A Chimeric Antigen Receptor That Binds to a Conserved Site on MICA

scientific article published on 09 October 2020

Antibody humanization by structure-based computational protein design.

scientific article

B-SIDER: Computational Algorithm for the Design of Complementary β-Sheet Sequences

scientific article published on 25 September 2019

Computationally driven antibody engineering enables simultaneous humanization and thermostabilization.

scientific article published on 21 June 2016

Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate.

scientific article

Computationally-driven identification of antibody epitopes.

scientific article published on 4 December 2017

Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination

scientific article published on 31 August 2020

Deimmunization of flagellin for repeated administration as a vaccine adjuvant

scientific article published in 2021

Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo.

scientific article published on May 2015

Developing stochastic models for spatial inference: bacterial chemotaxis

scientific article

DisruPPI: structure-based computational redesign algorithm for protein binding disruption.

scientific article

Effective inhibition of C3a-mediated pro-inflammatory response by a human C3a-specific protein binder

scientific article published on 18 February 2020

EpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function

scientific article

FREAD revisited: Accurate loop structure prediction using a database search algorithm.

scientific article

Fragment-based modeling of membrane protein loops: successes, failures, and prospects for the future

scientific article

Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris.

scientific article published on 21 February 2014

GradDock: Rapid Simulation and Tailored Ranking Functions for Peptide-MHC Class I Docking.

scientific article published on 18 September 2017

How long is a piece of loop?

scientific article

Mapping the Pareto optimal design space for a functionally deimmunized biotherapeutic candidate

scientific article

Predicting antibody complementarity determining region structures without classification ⬇️

scientific article published on October 20, 2011

Protein Modeling and Structural Prediction

Protein deimmunization via structure-based design enables efficient epitope deletion at high mutational loads

scientific article

Repeat Module-Based Rational Design of a Photoswitchable Protein for Light-Driven Control of Biological Processes

scientific article published on 23 July 2018

Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance.

scientific article published on 17 June 2015

Structure-guided deimmunization of therapeutic proteins

scientific article

Structure‐based redesign of proteins for minimal T‐cell epitope content ⬇️

scientific article published on January 8, 2013

List of works by Yoonjoo Choi

A Chimeric Antigen Receptor That Binds to a Conserved Site on MICA

Antibody humanization by structure-based computational protein design.

B-SIDER: Computational Algorithm for the Design of Complementary β-Sheet Sequences

Computationally driven antibody engineering enables simultaneous humanization and thermostabilization.

Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate.

Computationally-driven identification of antibody epitopes.

Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination

Deimmunization of flagellin for repeated administration as a vaccine adjuvant

Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo.

Developing stochastic models for spatial inference: bacterial chemotaxis

DisruPPI: structure-based computational redesign algorithm for protein binding disruption.

Effective inhibition of C3a-mediated pro-inflammatory response by a human C3a-specific protein binder

EpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function

FREAD revisited: Accurate loop structure prediction using a database search algorithm.

Fragment-based modeling of membrane protein loops: successes, failures, and prospects for the future

Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris.

GradDock: Rapid Simulation and Tailored Ranking Functions for Peptide-MHC Class I Docking.

How long is a piece of loop?

Mapping the Pareto optimal design space for a functionally deimmunized biotherapeutic candidate

Predicting antibody complementarity determining region structures without classification ⬇️

Protein Modeling and Structural Prediction

Protein deimmunization via structure-based design enables efficient epitope deletion at high mutational loads

Repeat Module-Based Rational Design of a Photoswitchable Protein for Light-Driven Control of Biological Processes

Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance.

Structure-guided deimmunization of therapeutic proteins

Structure‐based redesign of proteins for minimal T‐cell epitope content ⬇️