List of works - Carole Peyssonnaux

A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation.

scientific article

Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia‐inducible factor 2α ⬇️

scientific article published on June 7, 2012

Copper deficiency leads to anemia, duodenal hypoxia, upregulation of HIF-2α and altered expression of iron absorption genes in mice

scientific article

Critical role of HIF-1alpha in keratinocyte defense against bacterial infection

scientific article

Deletion of HIF-2α in the enterocytes decreases the severity of tissue iron loading in hepcidin knockout mice

scientific journal article

Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing

scientific article published on 01 April 2020

HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite

scientific article published on 2 July 2007

HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.

scientific article published on 6 April 2009

HIF1α and pancreatic β-cell development.

scientific article

Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis

scientific article

Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection.

scientific article published on 13 July 2011

Hypoferraemia during the early inflammatory response is dependent on tumour necrosis factor activity in a murine model of protracted peritonitis

scientific article published on 24 July 2012

Hypoxia interferes with aryl hydrocarbon receptor pathway in hCMEC/D3 human cerebral microvascular endothelial cells.

scientific article

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

scientific article

Investigating the real role of HIF-1 and HIF-2 in iron recycling by macrophages

scientific article published on 11 April 2014

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.

scientific article published on February 2015

Lack of iron-related phenotype in Sp6 intestinal knockout mice ⬇️

scientific article published on April 21, 2011

Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis

scientific article published on 20 February 2015

Myeloid HIFs are dispensable for resolution of inflammation during skeletal muscle regeneration

scientific article published on 06 March 2015

Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes

scientific article published in January 2008

Preeclamptic plasma induces transcription modifications involving the AP-1 transcriptional regulator JDP2 in endothelial cells

scientific article published on 10 October 2013

Pulmonary Iron Homeostasis in Hepcidin Knockout Mice.

scientific article published on 17 October 2017

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).

scientific article published in July 2007

Serum Iron Protects from Renal Postischemic Injury.

scientific article

TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens

scientific article published on 3 January 2006

Targeted disruption of hepcidin in the liver recapitulates the hemochromatotic phenotype

scientific journal article

The Raf/MEK/ERK pathway: new concepts of activation.

scientific article

The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions

scientific article published on 15 May 2013

The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells.

scientific article

[Hypoxia-inducible transcription factors (HIF): key regulators of iron metabolism?]

scientific article published on 01 February 2008

[Role of hepcidin in cutaneous infections]

scientific article published on 31 March 2020

List of works by Carole Peyssonnaux

A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation.

Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia‐inducible factor 2α ⬇️

Copper deficiency leads to anemia, duodenal hypoxia, upregulation of HIF-2α and altered expression of iron absorption genes in mice

Critical role of HIF-1alpha in keratinocyte defense against bacterial infection

Deletion of HIF-2α in the enterocytes decreases the severity of tissue iron loading in hepcidin knockout mice

Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing

HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite

HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.

HIF1α and pancreatic β-cell development.

Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis

Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection.

Hypoferraemia during the early inflammatory response is dependent on tumour necrosis factor activity in a murine model of protracted peritonitis

Hypoxia interferes with aryl hydrocarbon receptor pathway in hCMEC/D3 human cerebral microvascular endothelial cells.

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

Investigating the real role of HIF-1 and HIF-2 in iron recycling by macrophages

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.

Lack of iron-related phenotype in Sp6 intestinal knockout mice ⬇️

Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis

Myeloid HIFs are dispensable for resolution of inflammation during skeletal muscle regeneration

Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes

Preeclamptic plasma induces transcription modifications involving the AP-1 transcriptional regulator JDP2 in endothelial cells

Pulmonary Iron Homeostasis in Hepcidin Knockout Mice.

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).

Serum Iron Protects from Renal Postischemic Injury.

TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens

Targeted disruption of hepcidin in the liver recapitulates the hemochromatotic phenotype

The Raf/MEK/ERK pathway: new concepts of activation.

The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions

The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells.

[Hypoxia-inducible transcription factors (HIF): key regulators of iron metabolism?]

[Role of hepcidin in cutaneous infections]