List of works - Jens Høiriis Nielsen

Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans

scientific article published on 01 January 1986

Analysis of proinsulin and its conversion products by reversed-phase high-performance liquid chromatography

scientific article published on 01 May 1993

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

scientific article published in Nature

Beta cell adaptation in pregnancy: a tribute to Claes Hellerström

scientific article published on 08 April 2016

Beta cell proliferation and growth factors.

scientific article published in January 1999

Beta cell workshop 2013 Kyoto.

scientific article published on May 2013

Beta-cell function in isolated human pancreatic islets in long-term tissue culture.

scientific article published in January 1981

Beta-cell ontogeny: growth and death

scientific article published on 01 October 1997

Binding of zinc to insulin and some insulin derivatives studied by paper electrophoresis.

scientific article published in July 1969

Biosynthesis and release of thyrotropin-releasing hormone immunoreactivity in rat pancreatic islets in organ culture. Effects of age, glucose, and streptozotocin.

scientific article

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

scientific article

CXCL12/SDF-1 over-expression in human insulinomas and its biological relevance.

scientific article

Characterization of the inhibitory effect of growth hormone on primary preadipocyte differentiation

scientific article published on 01 August 1998

Co-ordinated regulation of neurogenin-3 expression in the maternal and fetal pancreas during pregnancy

scientific article published on 23 September 2014

Cytokine signalling in embryonic stem cells

scientific article

Cytokines cause functional and structural damage to isolated islets of Langerhans

scientific article published on 01 August 1985

Cytoplasmic sequences of the growth hormone receptor necessary for signal transduction.

scientific article published on February 1994

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

scientific article published on 01 June 1986

Direct effect of gonadal and contraceptive steroids on insulin release from mouse pancreatic islets in organ culture ⬇️

scientific article published on 01 February 1984

Direct effects of cyclosporin A on human pancreatic beta-cells

scientific article published on 01 September 1986

Direct long-term effect of hydrocortisone on insulin and glucagon release from mouse pancreatic islets in tissue culture

scientific article published on 01 April 1981

Dissociation between insulin secretion and DNA synthesis in cultured pancreatic islets

scientific article published on 01 January 1985

Effect of 5'-flanking sequence deletions on expression of the human insulin gene in transgenic mice.

scientific article published on May 1990

Effect of Diabetes on Circulating Pancreatic Hormones in Pregnant Rats and Their Offspring

scientific article published on 15 September 2016

Effect of interleukin-1 on the biosynthesis of proinsulin and insulin in isolated rat pancreatic islets

scientific article published on 01 January 1988

Effects of Growth Hormone, Prolactin, and Placental Lactogen on Insulin Content and Release, and Deoxyribonucleic Acid Synthesis in Cultured Pancreatic Islets ⬇️

scientific article published on 01 February 1982

Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase ⬇️

scientific article published on August 25, 1992

Expression and localization of microRNAs in perinatal rat pancreas: role of miR-21 in regulation of cholesterol metabolism

scientific article (publication date: 2011)

Expression of SMAD signal transduction molecules in the pancreas ⬇️

scientific article published on September 1, 2001

Expression of dominant-negative STAT5 inhibits growth hormone- and prolactin-induced proliferation of insulin-producing cells

scientific article published on 01 February 2001

Expression profiling of human genetic and protein interaction networks in type 1 diabetes

scientific article published on 17 July 2009

Expression, biosynthesis and release of preadipocyte factor-1/ delta-like protein/fetal antigen-1 in pancreatic beta-cells: possible physiological implications.

scientific article

Functional characteristics of neonatal rat β cells with distinct markers.

scientific article published on 19 December 2013

Glucagon-Like Peptide 1(7-36) Amide Stimulates Exocytosis in Human Pancreatic -Cells by Both Proximal and Distal Regulatory Steps in Stimulus-Secretion Coupling

scientific article published on 01 January 1998

Growth and function of the pancreatic beta cell in vitro: effects of glucose, hormones and serum factors on mouse, rat and human pancreatic islets in organ culture

scientific article published on 01 January 1985

Growth arrest specific protein (GAS) 6: a role in the regulation of proliferation and functional capacity of the perinatal rat beta cell.

scientific article

Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas.

scientific article published on September 1997

Growth hormone is a growth factor for the differentiated pancreatic beta-cell

scientific article published on 01 January 1989

Growth of the endocrine pancreas: the role of somatolactogenic hormones and receptors.

scientific article

High-performance liquid chromatography of rat and mouse islet polypeptides: potential risk of oxidation of methionine residues during sample preparation

scientific article published on 01 August 1990

Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation

scientific article published on 01 July 1995

Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation

scientific article published on 01 May 1996

Impact of fetal and neonatal environment on beta cell function and development of diabetes

scientific article published on 10 October 2014

Implications for the offspring of circulating factors involved in beta cell adaptation in pregnancy

scientific article published on 16 October 2014

Interleukin-1 beta-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine

scientific article published on 01 February 1996

Islet Amyloid Polypeptide and Insulin Expression Are Controlled Differently in Primary and Transformed Islet Cells ⬇️

scientific article published on January 1, 1991

Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

scientific article published on 01 May 1987

Long-term effect of Ph on B-cell function in isolated islets of langerhans in tissue culture ⬇️

scientific article published on September 1, 1978

Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins

scientific article published on 01 November 1999

Mechanisms of pancreatic islet cell destruction. Dose-dependent cytotoxic effect of soluble blood mononuclear cell mediators on isolated islets of Langerhans

scientific article published on 01 May 1986

MicroRNA-29a is up-regulated in beta-cells by glucose and decreases glucose-stimulated insulin secretion

scientific article published on 23 August 2012

Molecular dissection of the growth hormone receptor. Identification of distinct cytoplasmic domains corresponding to different signaling pathways

scientific article published on 01 September 1995

Molecular mechanism of growth hormone signalling

scientific article published on 01 April 1998

New approaches to therapy and diagnosis of diabetes.

scientific article published on February 1982

Pancreatic hormones are expressed on the surfaces of human and rat islet cells through exocytotic sites

scientific article published on 01 February 1989

Possible mechanisms involved in improved beta cell function in pregnant women with type 1 diabetes

scientific article published on 19 August 2020

Preservation of beta cell function in adult human pancreatic islets for several months in vitro.

scientific article published on February 1979

Rat insulinoma cells express both a 115-kDa growth hormone receptor and a 95-kDa prolactin receptor structurally related to the hepatic receptors ⬇️

scientific article published on May 25, 1990

Regulation of beta cell replication.

scientific article published on 07 September 2008

Regulation of integrin α6A by lactogenic hormones in rat pancreatic β-cells: Implications for the physiological adaptation to pregnancy

scientific article published on 13 February 2020

Regulation of prolactin receptor (PRLR) gene expression in insulin-producing cells. Prolactin and growth hormone activate one of the rat prlr gene promoters via STAT5a and STAT5b

scientific article published on 01 June 1999

Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration.

scientific article

Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function

scientific article published on 01 September 1995

Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo.

scientific article

Reversed-phase high-performance liquid chromatographic analyses of insulin biosynthesis in isolated rat and mouse islets

scientific article published on 01 January 1989

STAT5 activation by human GH protects insulin-producing cells against interleukin-1beta, interferon-gamma and tumour necrosis factor-alpha-induced apoptosis independent of nitric oxide production.

scientific article

STAT5 activity in pancreatic beta-cells influences the severity of diabetes in animal models of type 1 and 2 diabetes

scientific article published on 01 October 2006

Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells

article

Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

scientific article published on March 2006

Stimulatory effect of serum from diabetic patients on insulin release from mouse pancreatic islets maintained in tissue culture

scientific article published on 01 January 1981

Supravital dithizone staining in the isolation of human and rat pancreatic islets.

scientific article

The influence of body weight and cell size on lipogenesis and lipolysis of isolated rat fat cells.

scientific article published in December 1974

The influence of sexual hormones on lipogenesis and lipolysis in rat fat cells.

scientific article

The role of GH receptor tyrosine phosphorylation in Stat5 activation

scientific article published on 01 June 1997

The role of growth hormone and prolactin in beta cell growth and regeneration

scientific article published on January 1, 1992

The stimulatory effect of growth hormone, prolactin, and placental lactogen on beta-cell proliferation is not mediated by insulin-like growth factor-I

scientific article published on 01 August 1991

Trefoil factor 3 in perinatal pancreas is increased by gestational low protein diet and associated with accelerated β-cell maturation

scientific article published on 21 May 2018

Trefoil factors are expressed in human and rat endocrine pancreas: differential regulation by growth hormone

scientific journal article

Truncated glucagon-like peptide-1 (proglucagon 78-107 amide), an intestinal insulin-releasing peptide, has specific receptors on rat insulinoma cells (RIN 5AH)

scientific article published on 01 February 1988

Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity

scientific article published on 01 April 1987

Variations in insulin responsiveness in rat fat cells are due to metabolic differences rather than insulin binding.

scientific article

Workshop on programming beta cell development, impairment and regeneration

scientific article published on 01 March 2012

List of works by Jens Høiriis Nielsen

Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans

Analysis of proinsulin and its conversion products by reversed-phase high-performance liquid chromatography

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

Beta cell adaptation in pregnancy: a tribute to Claes Hellerström

Beta cell proliferation and growth factors.

Beta cell workshop 2013 Kyoto.

Beta-cell function in isolated human pancreatic islets in long-term tissue culture.

Beta-cell ontogeny: growth and death

Binding of zinc to insulin and some insulin derivatives studied by paper electrophoresis.

Biosynthesis and release of thyrotropin-releasing hormone immunoreactivity in rat pancreatic islets in organ culture. Effects of age, glucose, and streptozotocin.

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

CXCL12/SDF-1 over-expression in human insulinomas and its biological relevance.

Characterization of the inhibitory effect of growth hormone on primary preadipocyte differentiation

Co-ordinated regulation of neurogenin-3 expression in the maternal and fetal pancreas during pregnancy

Cytokine signalling in embryonic stem cells

Cytokines cause functional and structural damage to isolated islets of Langerhans

Cytoplasmic sequences of the growth hormone receptor necessary for signal transduction.

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

Direct effect of gonadal and contraceptive steroids on insulin release from mouse pancreatic islets in organ culture ⬇️

Direct effects of cyclosporin A on human pancreatic beta-cells

Direct long-term effect of hydrocortisone on insulin and glucagon release from mouse pancreatic islets in tissue culture

Dissociation between insulin secretion and DNA synthesis in cultured pancreatic islets

Effect of 5'-flanking sequence deletions on expression of the human insulin gene in transgenic mice.

Effect of Diabetes on Circulating Pancreatic Hormones in Pregnant Rats and Their Offspring

Effect of interleukin-1 on the biosynthesis of proinsulin and insulin in isolated rat pancreatic islets

Effects of Growth Hormone, Prolactin, and Placental Lactogen on Insulin Content and Release, and Deoxyribonucleic Acid Synthesis in Cultured Pancreatic Islets ⬇️

Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase ⬇️

Expression and localization of microRNAs in perinatal rat pancreas: role of miR-21 in regulation of cholesterol metabolism

Expression of SMAD signal transduction molecules in the pancreas ⬇️

Expression of dominant-negative STAT5 inhibits growth hormone- and prolactin-induced proliferation of insulin-producing cells

Expression profiling of human genetic and protein interaction networks in type 1 diabetes

Expression, biosynthesis and release of preadipocyte factor-1/ delta-like protein/fetal antigen-1 in pancreatic beta-cells: possible physiological implications.

Functional characteristics of neonatal rat β cells with distinct markers.

Glucagon-Like Peptide 1(7-36) Amide Stimulates Exocytosis in Human Pancreatic -Cells by Both Proximal and Distal Regulatory Steps in Stimulus-Secretion Coupling

Growth and function of the pancreatic beta cell in vitro: effects of glucose, hormones and serum factors on mouse, rat and human pancreatic islets in organ culture

Growth arrest specific protein (GAS) 6: a role in the regulation of proliferation and functional capacity of the perinatal rat beta cell.

Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas.

Growth hormone is a growth factor for the differentiated pancreatic beta-cell

Growth of the endocrine pancreas: the role of somatolactogenic hormones and receptors.

High-performance liquid chromatography of rat and mouse islet polypeptides: potential risk of oxidation of methionine residues during sample preparation

Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation

Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation

Impact of fetal and neonatal environment on beta cell function and development of diabetes

Implications for the offspring of circulating factors involved in beta cell adaptation in pregnancy

Interleukin-1 beta-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine

Islet Amyloid Polypeptide and Insulin Expression Are Controlled Differently in Primary and Transformed Islet Cells ⬇️

Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

Long-term effect of Ph on B-cell function in isolated islets of langerhans in tissue culture ⬇️

Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins

Mechanisms of pancreatic islet cell destruction. Dose-dependent cytotoxic effect of soluble blood mononuclear cell mediators on isolated islets of Langerhans

MicroRNA-29a is up-regulated in beta-cells by glucose and decreases glucose-stimulated insulin secretion

Molecular dissection of the growth hormone receptor. Identification of distinct cytoplasmic domains corresponding to different signaling pathways

Molecular mechanism of growth hormone signalling

New approaches to therapy and diagnosis of diabetes.

Pancreatic hormones are expressed on the surfaces of human and rat islet cells through exocytotic sites

Possible mechanisms involved in improved beta cell function in pregnant women with type 1 diabetes

Preservation of beta cell function in adult human pancreatic islets for several months in vitro.

Rat insulinoma cells express both a 115-kDa growth hormone receptor and a 95-kDa prolactin receptor structurally related to the hepatic receptors ⬇️

Regulation of beta cell replication.

Regulation of integrin α6A by lactogenic hormones in rat pancreatic β-cells: Implications for the physiological adaptation to pregnancy

Regulation of prolactin receptor (PRLR) gene expression in insulin-producing cells. Prolactin and growth hormone activate one of the rat prlr gene promoters via STAT5a and STAT5b

Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration.

Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function

Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo.

Reversed-phase high-performance liquid chromatographic analyses of insulin biosynthesis in isolated rat and mouse islets

STAT5 activation by human GH protects insulin-producing cells against interleukin-1beta, interferon-gamma and tumour necrosis factor-alpha-induced apoptosis independent of nitric oxide production.

STAT5 activity in pancreatic beta-cells influences the severity of diabetes in animal models of type 1 and 2 diabetes

Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells

Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

Stimulatory effect of serum from diabetic patients on insulin release from mouse pancreatic islets maintained in tissue culture

Supravital dithizone staining in the isolation of human and rat pancreatic islets.

The influence of body weight and cell size on lipogenesis and lipolysis of isolated rat fat cells.

The influence of sexual hormones on lipogenesis and lipolysis in rat fat cells.

The role of GH receptor tyrosine phosphorylation in Stat5 activation

The role of growth hormone and prolactin in beta cell growth and regeneration

The stimulatory effect of growth hormone, prolactin, and placental lactogen on beta-cell proliferation is not mediated by insulin-like growth factor-I

Trefoil factor 3 in perinatal pancreas is increased by gestational low protein diet and associated with accelerated β-cell maturation

Trefoil factors are expressed in human and rat endocrine pancreas: differential regulation by growth hormone

Truncated glucagon-like peptide-1 (proglucagon 78-107 amide), an intestinal insulin-releasing peptide, has specific receptors on rat insulinoma cells (RIN 5AH)