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List of works by Joachim Fandrey

A cordial affair - erythropoietin and cardioprotection

scientific article published on 01 August 2006

A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression

scientific article published on 7 February 2014

Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis.

scientific article published on 30 April 2012

Accumulation of HIF-1alpha under the influence of nitric oxide.

scientific article

Activation of hypoxia-inducible factor 1 in skeletal muscle cells after exposure to damaged muscle cell debris.

scientific article published on June 2011

Acupuncture-brain interactions as hypothesized by mood scale recordings

scientific article published on 22 May 2015

Acute hypoxia induces HIF-independent monocyte adhesion to endothelial cells through increased intercellular adhesion molecule-1 expression: the role of hypoxic inhibition of prolyl hydroxylase activity for the induction of NF-kappa B.

scientific article published on 23 June 2010

Altered pulmonary vascular reactivity in mice with excessive erythrocytosis.

scientific article

Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB.

scientific article published on June 2006

Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice.

scientific article published on 19 January 2017

Bringing European physiologists together

scientific article

Carotid body type I cells engage flavoprotein and Pin1 for oxygen sensing

scientific article published on 22 January 2020

Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha

scientific article published on 18 August 2004

Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin

scientific article published on 01 January 2001

Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species.

scientific article published on February 1997

Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma.

scientific article

Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.

scientific article

Cytosolic Ca(2+) levels and DNA synthesis of human umbilical vein endothelial cell cultures are unresponsive to thrombopoietin treatment.

scientific article published in January 2001

Decreased erythropoietin response in Plasmodium falciparum malaria‐associated anaemia ⬇️

scientific article published on November 1, 1997

Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity

scientific article

Developmental changes in the expression of transcription factors GATA-1, -2 and -3 during the onset of human medullary haematopoiesis

scientific article published in November 2002

Dose-dependent effects of levetiracetam after hypoxia and hypothermia in the neonatal mouse brain

scientific article published on 20 May 2016

Effects of antioxidant vitamins on renal and hepatic erythropoietin production

scientific journal article

Effects of modulators of the production and degradation of hydrogen peroxide on erythropoietin synthesis

scientific article published on 01 November 1998

Effects of neopterin and 7,8-dihydroneopterin on hypoxia-induced renal erythropoietin production

scientific article

Effects of recombinant human erythropoietin (rHuEPO) on tumor control in patients with cancer-induced anemia

scientific article published on 31 March 2005

Erythropoiesis--once more HIF!

scientific article published on 01 August 2008

Erythropoiesis: Physiology, pathophysiology, and algorithm for classification of the type of anemia

scientific article published in September 2015

Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury.

scientific article published on 14 July 2016

Erythropoietin gene expression in different areas of the developing human central nervous system.

scientific article

Erythropoietin gene expression is suppressed after lipopolysaccharide or interleukin-1 beta injections in rats

scientific journal article

Erythropoietin receptors on tumor cells: what do they mean?

scientific article published on January 2008

Examining the involvement of erythropoiesis-stimulating agents in tumor proliferation (erythropoietin receptors, receptor binding, signal transduction), angiogenesis, and venous thromboembolic events

scientific article published on January 2009

Expression of the thrombopoietin gene in human fetal and neonatal tissues

scientific article published on 01 July 1999

Expression of vascular endothelial growth factor during the development of cardiac hypertrophy in spontaneously hypertensive rats

scientific article published on 01 October 1998

Fluorescence Lifetime Imaging Microscopy (FLIM) as a Tool to Investigate Hypoxia-Induced Protein-Protein Interaction in Living Cells

scientific article published in January 2018

From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia

scientific article published on 30 August 2007

Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat.

scientific article published in February 2010

HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis

scientific article

Hemostasis and coagulation at a hematocrit level of 0.85: functional consequences of erythrocytosis

scientific article

Hepatic erythropoietin gene regulation by GATA-4.

scientific article published on 28 October 2003

Hepatic thrombopoietin mRNA is increased in acute inflammation

scientific journal article

Hepatocyte-supported serum-free culture of rat liver sinusoidal endothelial cells.

scientific article published in May 2000

High-altitude polycythemia

scientific article published on 01 January 2005

Highlight: sensing hypoxia in the cell and the organism

scientific article

Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells

scientific article published on 01 July 2000

Hypoxia induced gene expression: the specificity switch!

scientific article published in January 2015

Hypoxia-Dependent HIF-1 Activation Impacts on Tissue Remodeling in Graves' Ophthalmopathy-Implications for Smoking

scientific article published on 9 September 2016

Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site

scientific article published in September 2004

Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression

scientific article published on October 2006

Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia

scientific article published on 7 November 2014

Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells

scientific article

Hypoxia-inducible factor (HIF) 1alpha accumulation and HIF target gene expression are impaired after induction of endotoxin tolerance

scientific article published on May 2009

Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis

scientific article published on 29 July 2015

Hypoxia-inducible factor 1α is Essential for Macrophage-mediated Erythroblast Proliferation in Acute Friend Retrovirus Infection

scientific article published on 8 December 2017

Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: prospective observational clinical and cellular studies

scientific article published in June 2013

Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.

scientific article published on 22 June 2009

Identification of protein disulfide isomerase as a cardiomyocyte survival factor in ischemic cardiomyopathy

scientific article published on 20 August 2007

Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing

scientific article

Interleukin 1 beta and phorbol ester induce tumour necrosis factor alpha production in a hepatic cell line (HepG2).

scientific article

Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1

scientific article published on 01 September 1999

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

scientific article

Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis

scientific article published on 20 December 2017

Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis

scientific article published on 17 November 2017

Manganese augments nitric oxide synthesis in murine astrocytes: a new pathogenetic mechanism in manganism?

scientific article published on 01 January 1998

Measurement of ROS Levels and Membrane Potential Dynamics in the Intact Carotid Body Ex Vivo

scientific article published in January 2015

Measuring oxygen levels in Caco-2 cultures

scientific article

Membrane traffic control by hypoxia.

scientific article published on 26 April 2017

Mitochondrial DNA: An Endogenous Trigger for Immune Paralysis

scientific article published on 15 January 2016

Molecular imaging: into in vivo interaction of HIF-1alpha and HIF-2alpha with ARNT.

scientific article

Monitoring of cellular responses to hypoxia

scientific article

More insights into the CCN3/Connexin43 interaction complex and its role for signaling

scientific article published on May 2010

Multifocal animated imaging of changes in cellular oxygen and calcium concentrations and membrane potential within the intact adult mouse carotid body ex vivo

scientific article published on 27 April 2011

Myeloid hypoxia-inducible factor-1α is essential for skeletal muscle regeneration in mice.

scientific article published on 31 May 2013

NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum

scientific article

NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence

scientific article published on 04 August 2021

NO and TNF-alpha released from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells

scientific article published on 25 September 2002

Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software

scientific article

Nanostructure of specific chromatin regions and nuclear complexes.

scientific article published on 12 November 2005

Neopterin activates transcription factor nuclear factor-kappa B in vascular smooth muscle cells

scientific article published on 01 August 1996

Neural substrates for behaviorally conditioned immunosuppression in the rat.

scientific article

Nitric oxide affects the production of reactive oxygen species in hepatoma cells: implications for the process of oxygen sensing

scientific article published on 01 September 2000

Nitric oxide donors suppress erythropoietin production in vitro.

scientific article published on October 1996

Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

scientific article

Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.

scientific article published on 23 October 2006

No evidence for protective erythropoietin alpha signalling in rat hepatocytes

scientific article

Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors

scientific article

Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation

scientific article published on 4 October 2014

Nuclear oxygen sensing: induction of endogenous prolyl-hydroxylase 2 activity by hypoxia and nitric oxide

scientific article published on 6 September 2008

Optical Analysis of Hypoxia Inducible Factor (HIF)-1 Complex Assembly: Imaging of Cellular Oxygen Sensing

scientific article published on January 2016

Optical analysis of cellular oxygen sensing

scientific article published on 8 March 2017

Optical analysis of the HIF-1 complex in living cells by FRET and FRAP

scientific article published on 28 December 2006

Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy.

scientific article

Oxygen Radicals as Messengers in Oxygen-Dependent Gene Expression

scientific article published on 01 August 2000

Oxygen Sensitivity of Placental Trophoblast Connexins 43 and 46: A Role in Preeclampsia?

scientific article published on 27 May 2015

Oxygen and the cell

scientific article published in March 2004

Oxygen sensing and the activation of the hypoxia inducible factor 1 (HIF-1)--invited article

scientific article published on January 2009

Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling

scientific article published on 3 September 2012

Oxygen sensing in intestinal mucosal inflammation

scientific article published on 25 July 2015

Oxygen tension modulates beta-globin switching in embryoid bodies.

scientific article published in February 1999

Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression

scientific article

Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC ⬇️

scientific article published on March 15, 2011

Oxygen-sensing under the influence of nitric oxide

scientific article published on March 2010

Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis

scientific article published on 01 July 2000

Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis

scientific article published on 9 July 2015

Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice

scientific article published on 15 May 2020

Reactive oxygen species as regulators of oxygen dependent gene expression.

scientific article

Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1

scientific journal article

Regulating cellular oxygen sensing by hydroxylation.

scientific article published on 10 May 2006

Regulation of hypoxia-inducible factors during inflammation

scientific article published on January 2007

Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin.

scientific article published on 29 February 2016

Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis

scientific article published on 10 March 2015

Retraction: Hypoxia-Inducible Factor (HIF) 1α Accumulation and HIF Target Gene Expression Are Impaired after Induction of Endotoxin Tolerance

scientific article

Rocket fuel for the quantification of S-nitrosothiols. Highly specific reduction of S-nitrosothiols to thiols by methylhydrazine

scientific article published on 05 December 2012

Role of N-acetyl-N-nitroso-tryptophan as nitric oxide donor in the modulation of HIF-1-dependent signaling

scientific article published on May 2010

Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cells

scientific article published on April 2013

Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia

scientific article

Rounding up the usual suspects in O2 sensing: CO, NO, and H2S!

scientific article

Serum erythropoietin concentration in anaemia of visceral leishmaniasis (kala-azar) before and during antimonial therapy.

scientific article published on March 1998

Serum erythropoietin levels in patients with sepsis and septic shock

scientific article published on 01 November 1996

Severe blunt muscle trauma in rats: only marginal hypoxia in the injured area

scientific article

Suppression of the oxidative burst in murine microglia by nitric oxide

scientific article published on 01 April 1997

Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling

scientific article published on 10 November 2011

Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia

scientific article published on 19 August 2016

The HIF-1 response to simulated ischemia in mouse skeletal muscle cells neither enhances glycolysis nor prevents myotube cell death

scientific article

The Hypoxia-regulated Ectonucleotidase CD73 is a Host Determinant of HIV Latency

scientific article published on 4 August 2022

The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.

scientific article

The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9

scientific article

The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases

scientific article

The impact of N-nitrosomelatonin as nitric oxide donor in cell culture experiments

scientific article published on 31 July 2008

The influence of nickel and cobalt on putative members of the oxygen-sensing pathway of erythropoietin-producing HepG2 cells

scientific article

The influence of phenobarbital on cytochromes and reactive oxygen species in erythropoietin producing HepG2 cells

scientific article published on 01 December 1998

The proinflammatory cytokine interleukin 1beta and hypoxia cooperatively induce the expression of adrenomedullin in ovarian carcinoma cells through hypoxia inducible factor 1 activation

scientific article published on June 2005

Things get broken: the hypoxia-inducible factor prolyl hydroxylases in ischemic heart disease

scientific article published on 11 March 2019

Thrombopoietin gene expression in the developing human central nervous system

scientific article

Thrombopoietin production in wild-type and interleukin-6 knockout mice with acute inflammation.

scientific article

Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1.

scientific article published on 20 May 2004

Thyroid hormone induces hypoxia-inducible factor 1alpha gene expression through thyroid hormone receptor beta/retinoid x receptor alpha-dependent activation of hepatic leukemia factor

scientific article published on 31 January 2008

Tumor necrosis factor-alpha production by human hepatoma cell lines is resistant to drugs that are inhibitory to macrophages

scientific article published on 01 December 1998

Two-photon imaging of cellular activities in oxygen sensing tissues

scientific article

Type I cell ROS kinetics under hypoxia in the intact mouse carotid body ex vivo: a FRET-based study.

scientific article published on 15 October 2014

VEGF production, cell proliferation and apoptosis of human IGR 1 melanoma cells under nIFN-alpha/beta and rIFN-gamma treatment.

scientific article

Visualization of the three-dimensional organization of hypoxia-inducible factor-1 alpha and interacting cofactors in subnuclear structures

scientific article published on March 2004

Why not the liver instead of the kidney? ⬇️

scientific article published on August 30, 2012

ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia.

scientific article published in December 2003

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