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List of works by Constantin Coussios

A non-exothermic cell-embedding tissue-mimicking material for studies of ultrasound-induced hyperthermia and drug release ⬇️

scientific article published on February 13, 2013

A real-time controller for sustaining thermally relevant acoustic cavitation during ultrasound therapy ⬇️

scientific article published on December 1, 2010

Acoustic particle manipulation in a 40 kHz quarter-wavelength standing wave with an air boundary

scientific article published on 01 May 2012

Advances in systemic delivery of anti-cancer agents for the treatment of metastatic cancer

scientific article published on 15 April 2016

An acoustic microscopy technique to assess particle size and distribution following needle-free injection.

scientific article

Attenuation and de-focusing during high-intensity focused ultrasound therapy through peri-nephric fat.

scientific article

Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion with human blood ⬇️

scientific article published on July 4, 2013

Broadband Ultrasonic Attenuation Estimation and Compensation With Passive Acoustic Mapping

scientific article published on 20 August 2018

CFD modeling of an ultrasonic separator for the removal of lipid particles from pericardial suction blood

scientific article published on 29 July 2010

Calibration of ultrasound backscatter temperature imaging for high-intensity focused ultrasound treatment planning.

scientific article published on 3 July 2013

Cavitation and contrast: the use of bubbles in ultrasound imaging and therapy.

scientific article published on January 2010

Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound ⬇️

scientific article published on April 4, 2013

Cavitation-enhanced delivery of insulin in agar and porcine models of human skin.

scientific article published on 26 February 2015

Cavitation-enhanced delivery of macromolecules into an obstructed vessel.

scientific article published in November 2010

Cavitation-enhanced extravasation for drug delivery

scientific article published on 2 October 2011

Clinical trial protocol for TARDOX: a phase I study to investigate the feasibility of targeted release of lyso-thermosensitive liposomal doxorubicin (ThermoDox®) using focused ultrasound in patients with liver tumours.

scientific article published on 2 November 2017

Correlation of cavitation with ultrasound enhancement of thrombolysis

scientific article

Diffraction Effects and Compensation in Passive Acoustic Mapping.

scientific article published in February 2018

Effect of temperature on rectified diffusion during ultrasound-induced heating

scientific article published on 01 November 2011

Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound

scientific article

Enhancement and Passive Acoustic Mapping of Cavitation from Fluorescently Tagged Magnetic Resonance-Visible Magnetic Microbubbles In Vivo.

scientific article published on 22 September 2016

Exploitation of acoustic cavitation-induced microstreaming to enhance molecular transport.

scientific article published on 9 April 2014

Exploitation of sub-micron cavitation nuclei to enhance ultrasound-mediated transdermal transport and penetration of vaccines.

scientific article published on 11 July 2016

Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial

scientific article published on 15 January 2019

Gas-Stabilizing Gold Nanocones for Acoustically Mediated Drug Delivery

scientific article published on 25 April 2018

Hepatic Steatosis and Normothermic Perfusion—Preliminary Experiments in a Porcine Model ⬇️

scientific article published on August 15, 2011

Heterogeneous Tissue Characterization Using Ultrasound: A Comparison of Fractal Analysis Backscatter Models on Liver Tumors.

scientific article published on 5 April 2016

High intensity focused ultrasound: physical principles and devices.

scientific article published on March 2007

In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz.

scientific article

In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications

scientific article

Increasing the density of nanomedicines improves their ultrasound-mediated delivery to tumours

scientific article published on 12 May 2015

Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes.

scientific article

Layered acoustofluidic resonators for the simultaneous optical and acoustic characterisation of cavitation dynamics, microstreaming, and biological effects

scientific article published on 30 May 2018

Liver Transplantation After Ex Vivo Normothermic Machine Preservation: A Phase 1 (First-in-Man) Clinical Trial.

scientific article published on 11 January 2016

Liver splitting during normothermic organ preservation.

scientific article published on 22 December 2016

Long-term radiological and histological outcomes following selective internal radiation therapy to liver metastases from breast cancer

article

Magnetic targeting of microbubbles against physiologically relevant flow conditions

scientific article

Magnetic targeting to enhance microbubble delivery in an occluded microarterial bifurcation.

scientific article published on 10 August 2017

Mechanical approaches to oncological drug delivery

scientific article published on 01 October 2013

Nanoparticle-Loaded Protein-Polymer Nanodroplets for Improved Stability and Conversion Efficiency in Ultrasound Imaging and Drug Delivery

scientific article published on 11 August 2015

Non-invasive and real-time passive acoustic mapping of ultrasound-mediated drug delivery

scientific article published on 7 August 2014

Nonlinear acoustic properties of ex vivo bovine liver and the effects of temperature and denaturation.

scientific article

Oxygen carrying microbubbles for enhanced sonodynamic therapy of hypoxic tumours

scientific article published on 4 February 2015

Passive Acoustic Mapping Using Data-Adaptive Beamforming Based on Higher Order Statistics

scientific article published on 02 July 2018

Passive acoustic mapping of magnetic microbubbles for cavitation enhancement and localization.

scientific article published on 7 January 2015

Passive acoustic mapping utilizing optimal beamforming in ultrasound therapy monitoring

scientific article published on May 2015

Polymeric Cups for Cavitation-mediated Delivery of Oncolytic Vaccinia Virus.

scientific article

Preliminary Single-Center Canadian Experience of Human Normothermic Ex Vivo Liver Perfusion: Results of a Clinical Trial.

scientific article

Pro: The Case for Normothermic Machine Perfusion in Liver Transplantation.

scientific article published on 22 December 2017

Properties, characteristics and applications of microbubbles for sonothrombolysis.

scientific article published on 09 January 2014

Quantification of ultrasonic texture intra-heterogeneity via volumetric stochastic modeling for tissue characterization ⬇️

scientific article

Quantitative observations of cavitation activity in a viscoelastic medium.

scientific article published in November 2011

Real-time optical measurement of biologically relevant thermal damage in tissue-mimicking hydrogels containing bovine serum albumin.

scientific article published on January 2010

Real-time passive acoustic monitoring of HIFU-induced tissue damage.

scientific article published in June 2011

Real-time temperature estimation and monitoring of HIFU ablation through a combined modeling and passive acoustic mapping approach.

scientific article published on 6 August 2013

Role of acoustic cavitation in the delivery and monitoring of cancer treatment by high-intensity focused ultrasound (HIFU).

scientific article published on March 2007

Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial.

scientific article

Simulation of nonlinear propagation of biomedical ultrasound using pzflex and the Khokhlov-Zabolotskaya-Kuznetsov Texas code.

scientific article published in September 2016

Spatiotemporal Monitoring of High-Intensity Focused Ultrasound Therapy with Passive Acoustic Mapping ⬇️

scientific article published on October 24, 2011

Spatiotemporal evolution of cavitation dynamics exhibited by flowing microbubbles during ultrasound exposure.

scientific article published on November 2012

Successful transplantation of porcine liver grafts following 48-hour normothermic preservation

scientific article published on 27 November 2017

Targeting of Liposomes via PSGL1 for Enhanced Tumor Accumulation ⬇️

scientific article published on September 20, 2012

The 24-hour normothermic machine perfusion of discarded human liver grafts.

scientific article

The effect of particle density on ultrasound-mediated transport of nanoparticles

scientific article published on 25 October 2016

The effect of temperature and viscoelasticity on cavitation dynamics during ultrasonic ablation ⬇️

scientific article published on November 1, 2011

The role of normothermic extracorporeal perfusion in minimizing ischemia reperfusion injury.

scientific article published on April 2012

The significance of shape and orientation in single-particle weak-scatterer models

scientific article published on 01 September 2002

Thin-film sparse boundary array design for passive acoustic mapping during ultrasound therapy

scientific article published on October 1, 2012

Ultrasound-Propelled Nanocups for Drug Delivery.

scientific article

Ultrasound-enhanced drug delivery for cancer

scientific article (publication date: 4 November 2012)

Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent.

scientific article

Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model.

scientific article published on October 2011

Ultrasound-induced inertial cavitation from gas-stabilizing nanoparticles.

scientific article

Ultrasound-mediated cavitation does not decrease the activity of small molecule, antibody or viral-based medicines.

scientific article published on 10 January 2018

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