List of works by Curtis R Pickering

APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism

scientific article published on 6 September 2017

Abstract 2482: Key tumor suppressor genes inactivated by promoter methylation and somatic mutations in head and neck cancer

article

Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.

scientific article published on 25 August 2011

Bcl-2 inhibition or FBXW7 mutation sensitizes solid tumor cells to HDAC inhibition in vitro but could prove difficult to validate in patients

scientific article published on 01 March 2013

CDKN2A/p16 deletion in head and neck cancer cells is associated with Cdk2 activation, replication stress, and vulnerability to Chk1 inhibition

scientific article

Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53.

scientific article published on 09 July 2013

Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal.

scientific article

Comprehensive pharmacogenomic profiling of human papillomavirus-positive and -negative squamous cell carcinoma identifies sensitivity to aurora kinase inhibition in KMT2D mutants.

scientific article

Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates.

scientific article

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

scientific article

Disruption of TP63-miR-27a* Feedback Loop by Mutant TP53 in Head and Neck Cancer

scientific article published on 01 March 2020

Distinct pattern of TP53 mutations in human immunodeficiency virus-related head and neck squamous cell carcinoma

scientific article published on 20 October 2017

Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence

scientific article

Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients

scientific article

Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer.

scientific article

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

scientific article (publication date: 26 August 2011)

FXR silencing in human colon cancer by DNA methylation and KRAS signaling.

scientific article published on 31 October 2013

Functionally impactful TP53 mutations are associated with increased risk of extranodal extension in clinically advanced oral squamous cell carcinoma

scientific article published on 14 August 2020

Genetics and penile cancer: recent developments and implications

scientific article published on 01 July 2019

Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.

scientific article published on 21 September 2017

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.

scientific article published in April 2018

HRAS mutations and resistance to the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib in head and neck squamous cell carcinoma cells.

scientific article

High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinoma.

scientific article published on 20 May 2013

High-risk TP53 mutations are associated with extra nodal extension (ENE) in oral cavity squamous cell carcinoma (OSCC).

scientific article published on 12 January 2018

How will we recruit, train, and retain physicians and scientists to conduct translational cancer research?

scientific article

Human epidermal growth factor receptor 2/neu as a novel therapeutic target in sinonasal undifferentiated carcinoma.

scientific article published on 11 January 2016

Identification of novel diagnostic markers for sinonasal undifferentiated carcinoma

scientific article published on 01 April 2019

Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer.

scientific article published on 5 May 2017

Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers

scientific article published on 25 April 2013

Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer

scientific article

Lessons learned from next-generation sequencing in head and neck cancer

scientific article

Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2

article published in the Proceedings of the National Academy of Sciences of the United States of America

Mechanisms for the Generation of Two Quadruplications Associated with Split-Hand Malformation

scientific article

Mutation allele frequency threshold does not affect prognostic analysis using next-generation sequencing in oral squamous cell carcinoma

scientific article published on 24 July 2018

Mutational landscape of aggressive cutaneous squamous cell carcinoma

scientific article

Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors.

scientific article published on 23 January 2017

New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development

scientific article published on 4 September 2015

PDK1 Mediates NOTCH1-Mutated Head and Neck Squamous Carcinoma Vulnerability to Therapeutic PI3K/mTOR Inhibition

scientific article published on 15 February 2019

Predicting Outcome in Head and Neck Cancer: miRNAs with potentially big effects

scientific article published on 09 November 2018

Prevalence of promoter mutations in the TERT gene in oral cavity squamous cell carcinoma.

scientific article published on 23 February 2017

Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer

scientific article published on April 2016

Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation.

scientific article published on 8 August 2017

Risk Stratification of Oral Potentially Malignant Disorders in Fanconi Anemia Patients Using Autofluorescence Imaging and Cytology-On-A Chip Assay.

scientific article published on 23 February 2018

Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers.

scientific article

The Integrated Genomic Landscape of Thymic Epithelial Tumors

scientific article published in February 2018

The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma

scientific article published on 04 November 2020

Variations in HPV function are associated with survival in squamous cell carcinoma

scientific article published on 10 January 2019

Weekly paclitaxel, carboplatin, cetuximab, and cetuximab, docetaxel, cisplatin, and fluorouracil, followed by local therapy in previously untreated, locally advanced head and neck squamous cell carcinoma

scientific article published on 01 March 2019

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