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List of works by Yiguo Hu

A deep learning diagnostic platform for diffuse large B-cell lymphoma with high accuracy across multiple hospitals

scientific article published on 26 November 2020

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

scientific article

A novel rapid-onset high-penetrance plasmacytoma mouse model driven by deregulation of cMYC cooperating with KRAS12V in BALB/c mice.

scientific article

A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance

scientific article

A tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia.

scientific article

ALCAM-EGFR interaction regulates myelomagenesis

scientific article published on 01 December 2021

Antimyeloma Activity of a Multitargeted Kinase Inhibitor, AT9283, via Potent Aurora Kinase and STAT3 Inhibition Either Alone or in Combination with Lenalidomide ⬇️

scientific article published on March 23, 2011

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

scientific article

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma

scientific article

CSNK1α1 mediates malignant plasma cell survival

scientific article

Delineating the mTOR kinase pathway using a dual TORC1/2 inhibitor, AZD8055, in multiple myeloma

scientific article published on 29 August 2014

Discovery of New SIRT2 Inhibitors by Utilizing a Consensus Docking/Scoring Strategy and Structure-Activity Relationship Analysis

scientific article published on 16 March 2017

Dual inhibition of canonical and noncanonical NF-κB pathways demonstrates significant antitumor activities in multiple myeloma

scientific article

Functional ramifications for the loss of P-selectin expression on hematopoietic and leukemic stem cells

scientific article

Histone deacetylase 3 as a novel therapeutic target in multiple myeloma.

scientific article

Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma

scientific article

Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I-induced leukemia and suppresses leukemic stem cells.

scientific article published on 29 March 2007

Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia

scientific article

Pancreatic tumor eradication via selective Pin1 inhibition in cancer-associated fibroblasts and T lymphocytes engagement

scientific article published in 2022

Preclinical pharmacodynamic evaluation of drug candidate SKLB-178 in the treatment of non-small cell lung cancer

scientific article published on 11 January 2017

Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia

scientific article published on 18 April 2004

Survival regulation of leukemia stem cells

scientific article

Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.

scholarly article

Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma

scientific article

The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells

scientific article

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