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List of works by Francesco Fazi

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

scientific article (publication date: 2 December 2005)

A small-molecule targeting the microRNA binding domain of argonaute 2 improves the retinoic acid differentiation response of the acute promyelocytic leukemia cell line NB4.

scientific article

Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells

article

Argonaute 2 sustains the gene expression program driving human monocytic differentiation of acute myeloid leukemia cells.

scientific article

Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination

scientific article published on 01 January 2019

Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells

scientific article published on 20 July 2017

Chronic Inhibition of PDE5 Limits Pro-Inflammatory Monocyte-Macrophage Polarization in Streptozotocin-Induced Diabetic Mice

scientific article published on 11 May 2015

Circulating miR-21-5p and miR-148a-3p as emerging non-invasive biomarkers in thymic epithelial tumors

scientific article published on 17 November 2015

Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies

scientific article

Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2.

scientific article

Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.

scientific article

Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells

scientific article published on 13 August 2019

Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia

article

Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition

scientific article

Interplay Between N 6-Methyladenosine (m6A) and Non-coding RNAs in Cell Development and Cancer

scientific article published on 28 June 2019

MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks.

scientific article published on 21 July 2008

METTL3 regulates WTAP protein homeostasis

scientific article published on 23 July 2018

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

scientific article (publication date: 8 February 2002)

MicroRNA expression profiling of thymic epithelial tumors

scientific article published on 29 April 2014

MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function

scientific article

MicroRNA-regulated pathways in hematological malignancies: how to avoid cells playing out of tune

scientific article

MicroRNA: basic mechanisms and transcriptional regulatory networks for cell fate determination

scientific article

MicroRNAs and lymph node metastatic disease in lung cancer.

scientific article published on 27 December 2011

Molecular analysis of different classes of RNA molecules from formalin-fixed paraffin-embedded autoptic tissues: a pilot study.

scientific article published on 19 August 2014

Oncogenic MicroRNAs Characterization in Clear Cell Renal Cell Carcinoma

scientific article

PML/RARa Interferes with NRF2 Transcriptional Activity Increasing the Sensitivity to Ascorbate of Acute Promyelocytic Leukemia Cells

scientific article published on 30 December 2019

Paracrine Signaling from Breast Cancer Cells Causes Activation of ID4 Expression in Tumor-Associated Macrophages

scientific article published on 11 February 2020

Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression.

scientific article published on 10 February 2012

Radiogenomics in Clear Cell Renal Cell Carcinoma: Correlations Between Advanced CT Imaging (Texture Analysis) and MicroRNAs Expression

scientific article published on 01 January 2019

Regulation of Gdnf expression by retinoic acid in Sertoli cells

scientific article published on 05 February 2020

Retinoic acid and arsenic trioxide sensitize acute promyelocytic leukemia cells to ER stress.

scientific article

Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML

scientific article published on 01 December 2019

Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo.

scientific article

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma.

scientific article published on 13 June 2017

Selective delivery of doxorubicin by novel stimuli-sensitive nano-ferritins overcomes tumor refractoriness.

scientific article published on 11 August 2016

Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia

scientific article published on 01 September 2006

Small Molecules Targeting the miRNA-Binding Domain of Argonaute 2: From Computer-Aided Molecular Design to RNA Immunoprecipitation.

scientific article published in January 2017

Surface Plasmon Resonance: A Useful Strategy for the Identification of Small Molecule Argonaute 2 Protein Binders.

scientific article published in January 2017

The Methylated DNA Immunoprecipitation [MeDIP] to Investigate the Epigenetic Remodeling in Cell Fate Determination and Cancer Development.

scientific article published in January 2016

The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.

scientific article published on 27 September 2009

The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA.

scientific article

The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells.

scientific article published on 25 October 2012

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1.

scientific article

The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity

scientific article published on 20 February 2018

Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation

scientific article

Transcriptional fine-tuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors.

scientific article published on 18 October 2013

Tumor suppressor microRNAs: a novel non-coding alliance against cancer

scientific article

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