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List of works by Henk Dekker

A new mathematical pharmacodynamic model of clonogenic cancer cell death by doxorubicin

scientific article published on July 18, 2013

A tool for gene expression based PubMed search through combining data sources

scientific article (publication date: 12 August 2004)

Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature

scientific article

Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer.

scientific article published on 8 December 2014

Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib.

scientific article

Endovascular laser-tissue interactions redefined: shining light on novel windows of therapeutic opportunity beyond selective photothermolysis

scientific article published on 01 August 2010

Epidermal growth factor receptor-induced activator protein 1 activity controls density-dependent growth inhibition in normal rat kidney fibroblasts

scientific article published in October 2006

Evaluation of a tyrosine kinase peptide microarray for tyrosine kinase inhibitor therapy selection in cancer

scientific article published on 16 December 2016

Folate deprivation induces BCRP (ABCG2) expression and mitoxantrone resistance in Caco-2 cells.

scientific article

Induction of p53 Up-Regulated Modulator of Apoptosis Messenger RNA by Chemotherapeutic Treatment of Locally Advanced Breast Cancer

scientific article published in March 2005

Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome

scientific article published on 01 February 2020

Kinome profiling of non-canonical TRAIL signaling reveals RIP1-Src-STAT3-dependent invasion in resistant non-small cell lung cancer cells

scientific article

Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.

scientific article published on 6 October 2011

MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing

scientific article published on 5 October 2015

Molecular mechanisms and modulation of key pathways underlying the synergistic interaction of sorafenib with erlotinib in non-small-cell-lung cancer (NSCLC) cells.

scientific article published on January 2013

Molecular mechanisms underlying the antitumor activity of 3-aminopropanamide irreversible inhibitors of the epidermal growth factor receptor in non-small cell lung cancer.

scientific article published on January 2013

Phosphotyrosine-based-phosphoproteomics scaled-down to biopsy level for analysis of individual tumor biology and treatment selection

scientific article published on 22 April 2017

Platelet function is disturbed by the angiogenesis inhibitors sunitinib and sorafenib, but unaffected by bevacizumab

scientific article

Selection of Protein Kinase Inhibitors Based on Tumor Tissue Kinase Activity Profiles in Patients with Refractory Solid Malignancies: An Interventional Molecular Profiling Study

scientific article published on 17 July 2018

Simulation model of doxorubicin activity in islets of human breast cancer cells.

scientific article published in August 2003

Sunitinib activates Axl signaling in renal cell cancer.

scientific article published on 27 January 2016