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List of works by Sébastien Malinge

A subgroup of malignant fibrous histiocytomas is associated with genetic changes similar to those of well-differentiated liposarcomas.

scientific article

Constitutive activation of RAS/MAPK pathway cooperates with trisomy 21 and is therapeutically exploitable in Down syndrome B-cell leukemia

scientific article published on 27 March 2020

DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

scientific article published on 25 May 2015

Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes ⬇️

scientific article published on August 26, 2013

ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia.

scientific article published in March 2017

Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome

scientific article published on 20 May 2020

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

scientific article

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

scientific article published on 18 January 2013

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.

scientific article published on 22 February 2012

Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome

scientific article published on 12 January 2009

Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia.

scientific article

Mutational analysis of candidate tumor-associated genes in acute megakaryoblastic leukemia

scientific article published on 06 August 2009

Notch: of mice and men? ⬇️

scientific article published on December 16, 2010

Nucleophosmin status may influence the therapeutic decision in de novo acute myeloid leukemia with normal karyotype

scientific article published on 22 June 2006

Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia

scientific article published on 29 October 2019

Pediatric Acute Megakaryoblastic Leukemia: Multitasking Fusion Proteins and Oncogenic Cooperations.

scientific article published on 18 August 2017

Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition.

scientific article

The mitochondrial respiratory chain is essential for haematopoietic stem cell function.

scientific article published on 15 May 2017

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

scientific article

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