List of works - Angelika Schnieke

A frameshift mutation in GON4L is associated with proportionate dwarfism in Fleckvieh cattle

scientific article published on 31 March 2016

A frameshift mutation in GON4L is associated with proportionate dwarfism in Fleckvieh cattle

A method for the amidation of recombinant peptides expressed as intein fusion proteins in Escherichia coli

scientific article published on 01 October 2001

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

scientific article

A porcine model of familial adenomatous polyposis

scientific article published in August 2012

A porcine model of osteosarcoma

scientific article published on 14 March 2016

Advancing ovarian folliculometry with selective plane illumination microscopy

scientific article

Altered microRNA profiles during early colon adenoma progression in a porcine model of familial adenomatous polyposis

scientific article published on 10 October 2017

An X-linked human collagen transgene escapes X inactivation in a subset of cells ⬇️

scientific article published on November 1, 1992

Analysis of telomere length in Dolly, a sheep derived by nuclear transfer.

scientific article

Analysis of telomere lengths in cloned sheep

scientific article

Animal pharming, two decades on.

scientific article published on 29 July 2008

Annotation of the Domestic Pig Genome by Quantitative Proteogenomics.

scientific article published on 19 June 2017

Assembling multiple xenoprotective transgenes in pigs

scientific article published on 28 July 2018

Cell-Mediated Transgenesis in Rabbits: Chimeric and Nuclear Transfer Animals

article by Valeri Zakhartchenko et al published 13 October 2010 in Biology of Reproduction

Conservation of IGF2-H19 and IGF2R imprinting in sheep: effects of somatic cell nuclear transfer

scientific article published in December 2003

Cytokine-inducible promoters to drive dynamic transgene expression: The "Smart Graft" strategy

scientific article published on 17 August 2020

Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo

scientific article

DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.

scientific article

DNA microsatellite analysis of Dolly

scientific article published in Nature

Disclosure of erlotinib as a multikinase inhibitor in pancreatic ductal adenocarcinoma.

scientific article published on November 2011

Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus

scientific article

E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex

scientific article published on 9 April 2009

Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector

scientific article

Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases

scientific article published in 2011

Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing

scientific article published on 29 June 2016

Efficient production of transgenic cloned calves using preimplantation screening

scientific article

Elevated expression of p53 in early colon polyps in a pig model of human familial adenomatous polyposis

scientific article published on 25 August 2018

Embryonic lethal mutation in mice induced by retrovirus insertion into the alpha 1(I) collagen gene.

scientific article published in July 1983

Endogenous Moloney leukemia virus in nonviremic Mov substrains of mice carries defects in the proviral genome.

scientific article published on February 1983

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.

scientific article

Fetal growth restriction caused by MIMT1 deletion alters brain transcriptome in cattle

scientific article published on 29 May 2013

Generation of functional cardiomyocytes from rat embryonic and induced pluripotent stem cells using feeder-free expansion and differentiation in suspension culture.

scientific article

Genetically engineered pigs as models for human disease

scientific article published on 22 January 2018

Genetically modified pigs to model human diseases

scientific article published on February 2014

Germline gene polymorphisms predisposing domestic mammals to carcinogenesis

scientific article

Germline integration of moloney murine leukemia virus at the Mov13 locus leads to recessive lethal mutation and early embryonic death.

scientific article

HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA.

scientific article

Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice

scientific article

Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle

scientific article

Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts ⬇️

scientific article published on December 19, 1997

Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos

scientific article published on April 1990

Hybrid voltage sensor imaging of eGFP-F expressing neurons in chicken midbrain slices

scientific article published on 4 June 2014

Identification of a novel HaeIII PCR-RFLP in the SLA DQB gene

article

In frame exon skipping in UBE3B is associated with developmental disorders and increased mortality in cattle

scientific article

In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging

scientific article

Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs

scientific article

Infectivity and structure of molecular clones obtained from two genetically transmitted Moloney leukemia proviral genomes

scientific article published on April 1982

Introduction of the human pro alpha 1(I) collagen gene into pro alpha 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen

scientific article

Lactation is disrupted by alpha-lactalbumin deficiency and can be restored by human alpha-lactalbumin gene replacement in mice

scientific article

MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors

scientific article

Maternal placenta modulates a deleterious fetal mutation

scientific article

Method for producing transgenic bovine embryos from in vitro matured and fertilized oocytes.

scientific article published in October 1993

Non-CpG hypermethylation in placenta of mutation-induced intrauterine growth restricted bovine foetuses.

scientific article

Non-invasive assessment of porcine oocyte quality by supravital staining of cumulus-oocyte complexes with lissamine green B.

scientific article published in June 2016

Oncogenic KRAS signalling in pancreatic cancer

scientific article

PEG3 domain gene expression in maternal and foetal placenta in intrauterine growth restricted bovine foetuses

scientific article published on 5 November 2015

Pigs as models of human cancers

scientific article published on 21 April 2016

Polymorphism in 3′ untranslated region of the pig PPARA gene influences its transcript level and is associated with adipose tissue accumulation1

article

Polymorphisms in the promoter region of the adiponectin (ADIPOQ) gene are presumably associated with transcription level and carcass traits in pigs.

scientific article

Porcine endogenous retroviruses: Quantification of the copy number in cell lines, pig breeds, and organs

scientific article published on 01 July 2018

Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression

scientific article published on 26 July 2017

Precondition your donor pig for your successful allograft!

scientific article published on 07 June 2020

Presence of endocrine and exocrine markers in EGFP-positive cells from the developing pancreas of a nestin/EGFP mouse

scientific article

Production of gene-targeted sheep by nuclear transfer from cultured somatic cells

scientific article (publication date: 29 June 2000)

Purification and Characterization of a Population of EGFP-Expressing Cells from the Developing Pancreas of a Neurogenin3/EGFP Transgenic Mouse

scientific article published on January 2005

RNA Interference in Pigs: Comparison of RNAi Test Systems and Expression Vectors

scientific article published on 01 May 2011

Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

scientific article

Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus.

scientific article

The new pig on the block: modelling cancer in pigs

scientific article published on 08 June 2013

The role of means and goals in technology acceptance. A differentiated landscape of public perceptions of pharming

scientific article published on 18 September 2009

Transgenic Cattle Resulting from Biopsied Embryos: Expression of c-ski in a Transgenic Calf

scientific article published on 01 March 1994

Truncation of MIMT1 gene in the PEG3 domain leads to major changes in placental gene expression and stillbirth in cattle.

scientific article published in June 2012

Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

scientific article published on February 1994

Viable Offspring Derived from Fetal And Adult Mammalian Cells

scientific article published on 01 January 2007

Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2

scientific article published on 08 October 2019

Viable pigs with a conditionally-activated oncogenic KRAS mutation

scientific article published on 26 February 2015

Xenotransplantation of porcine islet cells as a potential option for the treatment of type 1 diabetes in the future

scientific article

List of works by Angelika Schnieke

A frameshift mutation in GON4L is associated with proportionate dwarfism in Fleckvieh cattle

A frameshift mutation in GON4L is associated with proportionate dwarfism in Fleckvieh cattle

A method for the amidation of recombinant peptides expressed as intein fusion proteins in Escherichia coli

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

A porcine model of familial adenomatous polyposis

A porcine model of osteosarcoma

Advancing ovarian folliculometry with selective plane illumination microscopy

Altered microRNA profiles during early colon adenoma progression in a porcine model of familial adenomatous polyposis

An X-linked human collagen transgene escapes X inactivation in a subset of cells ⬇️

Analysis of telomere length in Dolly, a sheep derived by nuclear transfer.

Analysis of telomere lengths in cloned sheep

Animal pharming, two decades on.

Annotation of the Domestic Pig Genome by Quantitative Proteogenomics.

Assembling multiple xenoprotective transgenes in pigs

Cell-Mediated Transgenesis in Rabbits: Chimeric and Nuclear Transfer Animals

Conservation of IGF2-H19 and IGF2R imprinting in sheep: effects of somatic cell nuclear transfer

Cytokine-inducible promoters to drive dynamic transgene expression: The "Smart Graft" strategy

Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo

DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.

DNA microsatellite analysis of Dolly

Disclosure of erlotinib as a multikinase inhibitor in pancreatic ductal adenocarcinoma.

Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus

E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex

Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector

Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases

Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing

Efficient production of transgenic cloned calves using preimplantation screening

Elevated expression of p53 in early colon polyps in a pig model of human familial adenomatous polyposis

Embryonic lethal mutation in mice induced by retrovirus insertion into the alpha 1(I) collagen gene.

Endogenous Moloney leukemia virus in nonviremic Mov substrains of mice carries defects in the proviral genome.

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.

Fetal growth restriction caused by MIMT1 deletion alters brain transcriptome in cattle

Generation of functional cardiomyocytes from rat embryonic and induced pluripotent stem cells using feeder-free expansion and differentiation in suspension culture.

Genetically engineered pigs as models for human disease

Genetically modified pigs to model human diseases

Germline gene polymorphisms predisposing domestic mammals to carcinogenesis

Germline integration of moloney murine leukemia virus at the Mov13 locus leads to recessive lethal mutation and early embryonic death.

HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA.

Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice

Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle

Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts ⬇️

Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos

Hybrid voltage sensor imaging of eGFP-F expressing neurons in chicken midbrain slices

Identification of a novel HaeIII PCR-RFLP in the SLA DQB gene

In frame exon skipping in UBE3B is associated with developmental disorders and increased mortality in cattle

In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging

Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs

Infectivity and structure of molecular clones obtained from two genetically transmitted Moloney leukemia proviral genomes

Introduction of the human pro alpha 1(I) collagen gene into pro alpha 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen

Lactation is disrupted by alpha-lactalbumin deficiency and can be restored by human alpha-lactalbumin gene replacement in mice

MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors

Maternal placenta modulates a deleterious fetal mutation

Method for producing transgenic bovine embryos from in vitro matured and fertilized oocytes.

Non-CpG hypermethylation in placenta of mutation-induced intrauterine growth restricted bovine foetuses.

Non-invasive assessment of porcine oocyte quality by supravital staining of cumulus-oocyte complexes with lissamine green B.

Oncogenic KRAS signalling in pancreatic cancer

PEG3 domain gene expression in maternal and foetal placenta in intrauterine growth restricted bovine foetuses

Pigs as models of human cancers

Polymorphism in 3′ untranslated region of the pig PPARA gene influences its transcript level and is associated with adipose tissue accumulation1

Polymorphisms in the promoter region of the adiponectin (ADIPOQ) gene are presumably associated with transcription level and carcass traits in pigs.

Porcine endogenous retroviruses: Quantification of the copy number in cell lines, pig breeds, and organs

Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression

Precondition your donor pig for your successful allograft!

Presence of endocrine and exocrine markers in EGFP-positive cells from the developing pancreas of a nestin/EGFP mouse

Production of gene-targeted sheep by nuclear transfer from cultured somatic cells

Purification and Characterization of a Population of EGFP-Expressing Cells from the Developing Pancreas of a Neurogenin3/EGFP Transgenic Mouse

RNA Interference in Pigs: Comparison of RNAi Test Systems and Expression Vectors

Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus.

The new pig on the block: modelling cancer in pigs

The role of means and goals in technology acceptance. A differentiated landscape of public perceptions of pharming

Transgenic Cattle Resulting from Biopsied Embryos: Expression of c-ski in a Transgenic Calf

Truncation of MIMT1 gene in the PEG3 domain leads to major changes in placental gene expression and stillbirth in cattle.

Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

Viable Offspring Derived from Fetal And Adult Mammalian Cells

Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2

Viable pigs with a conditionally-activated oncogenic KRAS mutation

Xenotransplantation of porcine islet cells as a potential option for the treatment of type 1 diabetes in the future