List of works - Evangelos Pazarentzos

AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas

scientific article

Adaptive stress signaling in targeted cancer therapy resistance

scientific article

Anticancer gene transfer for cancer gene therapy.

scientific article published on January 2014

CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex.

scientific article published on 12 February 2014

De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF.

scientific article

De-ubiquitinating proteases USP2a and USP2c cause apoptosis by stabilising RIP1 ⬇️

scientific article published on May 30, 2012

Dose-dependent neuroprotection of VEGF₁₆₅ in Huntington's disease striatum

scientific article

Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction ⬇️

scientific article published on December 24, 2010

IκΒα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention.

scientific article

Mitochondrial Ca(2+) influx targets cardiolipin to disintegrate respiratory chain complex II for cell death induction

scientific article

NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer

scientific article

Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution.

scientific article published on 13 March 2017

Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3Cβ(D1067V) kinase domain mutation.

scientific article published on 18 May 2015

RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.

scientific article published on 24 August 2015

Stefan Grimm, 1963-2014, a tragic loss for the scientific community.

scientific article published in February 2015

Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers

scientific article published on 01 August 2019

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

scientific article published on 09 February 2015

The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis

scientific article

The transporter and permeability interactions of asymmetric dimethylarginine (ADMA) and L-arginine with the human blood-brain barrier in vitro.

scientific article published on 15 July 2016

List of works by Evangelos Pazarentzos

AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas

Adaptive stress signaling in targeted cancer therapy resistance

Anticancer gene transfer for cancer gene therapy.

CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex.

De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF.

De-ubiquitinating proteases USP2a and USP2c cause apoptosis by stabilising RIP1 ⬇️

Dose-dependent neuroprotection of VEGF₁₆₅ in Huntington's disease striatum

Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction ⬇️

IκΒα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention.

Mitochondrial Ca(2+) influx targets cardiolipin to disintegrate respiratory chain complex II for cell death induction

NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer

Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution.

Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3Cβ(D1067V) kinase domain mutation.

RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.

Stefan Grimm, 1963-2014, a tragic loss for the scientific community.

Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis

The transporter and permeability interactions of asymmetric dimethylarginine (ADMA) and L-arginine with the human blood-brain barrier in vitro.