List of works - Simon Heath

A Follow-Up Study of a Genome-wide Association Scan Identifies a Susceptibility Locus for Venous Thrombosis on Chromosome 6p24.1

scholarly article by Pierre-Emmanuel Morange et al published April 2010 in American Journal of Human Genetics

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

scientific article

A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1.

scientific article

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium

scientific article

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

scientific article

Common and rare variant analysis in early-onset bipolar disorder vulnerability

scientific article published on 11 August 2014

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.

scientific article published on 12 April 2016

Correction: Genetic Determination and Linkage Mapping of Plasmodium falciparum Malaria Related Traits in Senegal

scientific article published on 30 April 2008

Correction: Genetic Structure of Europeans: A View from the North–East.

scientific article

Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage.

scientific article published on November 2016

Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems

scientific article published in November 2016

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils

scientific article published on 01 September 2018

Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures.

scientific article

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

From Wet-Lab to Variations: Concordance and Speed of Bioinformatics Pipelines for Whole Genome and Whole Exome Sequencing.

scientific article published on 08 September 2016

Genetic determination and linkage mapping of Plasmodium falciparum malaria related traits in Senegal

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Genetic structure of Europeans: a view from the North-East

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

scientific article

Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder

scientific article

Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot

scientific journal article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

scientific article (publication date: October 2009)

Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16.

scientific article published on 26 May 2013

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

scientific journal article

Impact of DNA methylation on 3D genome structure

scientific article published on 28 May 2021

Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway Analysis

article

Increased DNA methylation variability in type 1 diabetes across three immune effector cell types.

scientific article

Information recovery from low coverage whole-genome bisulfite sequencing.

scientific article published on 27 June 2016

Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease.

scientific article published on 25 November 2016

Investigation of the fine structure of European populations with applications to disease association studies

scientific article published in December 2008

Lung cancer susceptibility locus at 5p15.33

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New technologies for DNA analysis--a review of the READNA Project

scientific article

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Selective single molecule sequencing and assembly of a human Y chromosome of African origin

scientific article published in Nature Communications

Systematic Analysis of Candidate Genes for Alzheimer's Disease in a French, Genome-Wide Association Study

article

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior

scientific article

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

scientific article published on 21 May 2018

Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene

scientific article

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene

scientific article

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate

scientific article published on 13 September 2018

Variation in genomic landscape of clear cell renal cell carcinoma across Europe

scientific article published on 29 October 2014

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.

scientific article

Whole-genome fingerprint of the DNA methylome during human B cell differentiation

scientific article

β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

scientific article

List of works by Simon Heath

A Follow-Up Study of a Genome-wide Association Scan Identifies a Susceptibility Locus for Venous Thrombosis on Chromosome 6p24.1

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1.

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

A genome-wide association search for type 2 diabetes genes in African Americans

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

Common and rare variant analysis in early-onset bipolar disorder vulnerability

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

Common variants at five new loci associated with early-onset inflammatory bowel disease

Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.

Correction: Genetic Determination and Linkage Mapping of Plasmodium falciparum Malaria Related Traits in Senegal

Correction: Genetic Structure of Europeans: A View from the North–East.

Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage.

Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils

Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures.

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

From Wet-Lab to Variations: Concordance and Speed of Bioinformatics Pipelines for Whole Genome and Whole Exome Sequencing.

Genetic determination and linkage mapping of Plasmodium falciparum malaria related traits in Senegal

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Genetic structure of Europeans: a view from the North-East

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder

Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16.

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

Impact of DNA methylation on 3D genome structure

Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway Analysis

Increased DNA methylation variability in type 1 diabetes across three immune effector cell types.

Information recovery from low coverage whole-genome bisulfite sequencing.

Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease.

Investigation of the fine structure of European populations with applications to disease association studies

Lung cancer susceptibility locus at 5p15.33

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

New technologies for DNA analysis--a review of the READNA Project

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Selective single molecule sequencing and assembly of a human Y chromosome of African origin

Systematic Analysis of Candidate Genes for Alzheimer's Disease in a French, Genome-Wide Association Study

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate

Variation in genomic landscape of clear cell renal cell carcinoma across Europe

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.

Whole-genome fingerprint of the DNA methylome during human B cell differentiation

β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance