List of works - Nathalie Augé

4-Hydroxynonenal Contributes to Angiogenesis through a Redox-Dependent Sphingolipid Pathway: Prevention by Hydralazine Derivatives

scientific article

A deletion in the gene encoding sphingomyelin phosphodiesterase 3 (Smpd3) results in osteogenesis and dentinogenesis imperfecta in the mouse

scientific article published on 17 July 2005

Annexin II-dependent actin remodelling evoked by hydrogen peroxide requires the metalloproteinase/sphingolipid pathway

scientific article

Detection of intracellular reactive oxygen species in cultured cells using fluorescent probes

scientific article published on 01 January 2002

Dual signaling evoked by oxidized LDLs in vascular cells.

scientific article published on 8 February 2017

Effect of FTY720 on apoptosis of smooth muscle cells.

scientific article published in October 2007

FTY720 Inhibits Tumor Necrosis Factor-alpha-Induced Proliferation and Extracellular Signal-Regulated Kinase Phosphorylation of Human Smooth Muscle Cells.

scientific article

HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF-kappaB activation in smooth muscle cells.

scientific article published on 5 February 2003

HLA class I antibodies provoke graft arteriosclerosis in human arteries transplanted into SCID/beige mice

scientific article published on 01 November 2009

High-density lipoproteins prevent the oxidized low-density lipoprotein-induced epidermal [corrected] growth factor receptor activation and subsequent matrix metalloproteinase-2 upregulation.

scientific article

Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDL

scientific article

Hyperglycemia and glycation in diabetic complications.

scientific article published on December 2009

Implications of lag time concept in the oxidation of LDL

scientific article published on 01 June 1998

Integrin alpha(v)beta(3), metalloproteinases, and sphingomyelinase-2 mediate urokinase mitogenic effect.

scientific article

MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway

scientific article published on 10 April 2007

Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction.

scientific article

Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis

scientific article published on 15 May 2007

Mildly oxidized LDL evokes a sustained Ca(2+)-dependent retraction of vascular smooth muscle cells

scientific article published on 01 October 1996

Mitochondria play a central role in apoptosis induced by alpha-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling

scientific article published in April 2003

Mitochondrial oxidative stress is modulated by oleic acid via an epidermal growth factor receptor-dependent activation of glutathione peroxidase

scientific article published on November 2002

Oxidized LDL, T lymphocytes, and graft atherosclerosis

scientific article published on 01 August 1997

Oxidized low-density lipoprotein, a two-faced Janus in coronary artery disease?

scientific article published in August 1998

Oxidized low-density lipoprotein-induced apoptosis

scientific article

Oxidized low-density lipoproteins trigger endoplasmic reticulum stress in vascular cells: prevention by oxygen-regulated protein 150 expression.

scientific article

Pancreatic bile salt-dependent lipase induces smooth muscle cells proliferation.

scientific article

Pathological aspects of lipid peroxidation.

scientific article

Potential role for ceramide in mitogen-activated protein kinase activation and proliferation of vascular smooth muscle cells induced by oxidized low density lipoprotein

scientific article published on 01 May 1998

Preconditioning by mitochondrial reactive oxygen species improves the proangiogenic potential of adipose-derived cells-based therapy

scientific article published on 07 May 2009

Proliferation and wound healing of vascular cells trigger the generation of extracellular reactive oxygen species and LDL oxidation.

scientific article published in December 2003

Proliferative and cytotoxic effects of mildly oxidized low-density lipoproteins on vascular smooth-muscle cells.

scientific article published on August 1995

Protective effect of high-density lipoprotein-based therapy in a model of embolic stroke.

scientific article

Protein Disulfide Isomerase Modification and Inhibition Contribute to ER Stress and Apoptosis Induced by Oxidized Low Density Lipoproteins ⬇️

scientific article published on December 21, 2012

Resveratrol inhibits the mTOR mitogenic signaling evoked by oxidized LDL in smooth muscle cells.

scientific article published on 24 November 2008

Retrovirus-mediated correction of the metabolic defect in cultured Farber disease cells.

scientific article published on May 1999

Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway.

scientific article published on 5 February 2007

Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.

scientific article

Role of Sphingosine-1-Phosphate in Transplant Vasculopathy Evoked by Anti-HLA Antibody

scientific article published on 30 April 2015

Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase

scientific article published on 01 July 1999

Sphingolipid mediators in cardiovascular cell biology and pathology

scientific article

Sphingomyelin metabolites in vascular cell signaling and atherogenesis

scientific article

Sphingomyelin-degrading pathways in human cells role in cell signalling

scientific article

Stress-induced sphingolipid signaling: role of type-2 neutral sphingomyelinase in murine cell apoptosis and proliferation.

scientific article published on 23 March 2010

Synthesis and biological evaluation of diarylheptanoids as potential antioxidant and anti-inflammatory agents.

scientific article

The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts.

scientific article

The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL.

scientific article published on 4 February 2016

The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation

scientific article published on 01 August 1996

The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator.

scientific article published on July 2004

Two distinct calcium-dependent mitochondrial pathways are involved in oxidized LDL-induced apoptosis.

scientific article published on 23 December 2004

nSMase2 (Type 2-Neutral Sphingomyelinase) Deficiency or Inhibition by GW4869 Reduces Inflammation and Atherosclerosis in Apoe-/- Mice

scientific article published on 24 May 2018

List of works by Nathalie Augé

4-Hydroxynonenal Contributes to Angiogenesis through a Redox-Dependent Sphingolipid Pathway: Prevention by Hydralazine Derivatives

A deletion in the gene encoding sphingomyelin phosphodiesterase 3 (Smpd3) results in osteogenesis and dentinogenesis imperfecta in the mouse

Annexin II-dependent actin remodelling evoked by hydrogen peroxide requires the metalloproteinase/sphingolipid pathway

Detection of intracellular reactive oxygen species in cultured cells using fluorescent probes

Dual signaling evoked by oxidized LDLs in vascular cells.

Effect of FTY720 on apoptosis of smooth muscle cells.

FTY720 Inhibits Tumor Necrosis Factor-alpha-Induced Proliferation and Extracellular Signal-Regulated Kinase Phosphorylation of Human Smooth Muscle Cells.

HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF-kappaB activation in smooth muscle cells.

HLA class I antibodies provoke graft arteriosclerosis in human arteries transplanted into SCID/beige mice

High-density lipoproteins prevent the oxidized low-density lipoprotein-induced epidermal [corrected] growth factor receptor activation and subsequent matrix metalloproteinase-2 upregulation.

Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDL

Hyperglycemia and glycation in diabetic complications.

Implications of lag time concept in the oxidation of LDL

Integrin alpha(v)beta(3), metalloproteinases, and sphingomyelinase-2 mediate urokinase mitogenic effect.

MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway

Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction.

Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis

Mildly oxidized LDL evokes a sustained Ca(2+)-dependent retraction of vascular smooth muscle cells

Mitochondria play a central role in apoptosis induced by alpha-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling

Mitochondrial oxidative stress is modulated by oleic acid via an epidermal growth factor receptor-dependent activation of glutathione peroxidase

Oxidized LDL, T lymphocytes, and graft atherosclerosis

Oxidized low-density lipoprotein, a two-faced Janus in coronary artery disease?

Oxidized low-density lipoprotein-induced apoptosis

Oxidized low-density lipoproteins trigger endoplasmic reticulum stress in vascular cells: prevention by oxygen-regulated protein 150 expression.

Pancreatic bile salt-dependent lipase induces smooth muscle cells proliferation.

Pathological aspects of lipid peroxidation.

Potential role for ceramide in mitogen-activated protein kinase activation and proliferation of vascular smooth muscle cells induced by oxidized low density lipoprotein

Preconditioning by mitochondrial reactive oxygen species improves the proangiogenic potential of adipose-derived cells-based therapy

Proliferation and wound healing of vascular cells trigger the generation of extracellular reactive oxygen species and LDL oxidation.

Proliferative and cytotoxic effects of mildly oxidized low-density lipoproteins on vascular smooth-muscle cells.

Protective effect of high-density lipoprotein-based therapy in a model of embolic stroke.

Protein Disulfide Isomerase Modification and Inhibition Contribute to ER Stress and Apoptosis Induced by Oxidized Low Density Lipoproteins ⬇️

Resveratrol inhibits the mTOR mitogenic signaling evoked by oxidized LDL in smooth muscle cells.

Retrovirus-mediated correction of the metabolic defect in cultured Farber disease cells.

Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway.

Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.

Role of Sphingosine-1-Phosphate in Transplant Vasculopathy Evoked by Anti-HLA Antibody

Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase

Sphingolipid mediators in cardiovascular cell biology and pathology

Sphingomyelin metabolites in vascular cell signaling and atherogenesis

Sphingomyelin-degrading pathways in human cells role in cell signalling

Stress-induced sphingolipid signaling: role of type-2 neutral sphingomyelinase in murine cell apoptosis and proliferation.

Synthesis and biological evaluation of diarylheptanoids as potential antioxidant and anti-inflammatory agents.

The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts.

The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL.

The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation

The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator.

Two distinct calcium-dependent mitochondrial pathways are involved in oxidized LDL-induced apoptosis.

nSMase2 (Type 2-Neutral Sphingomyelinase) Deficiency or Inhibition by GW4869 Reduces Inflammation and Atherosclerosis in Apoe-/- Mice