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List of works by Il-Mi Okazaki

A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.

scientific article

A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

scientific article

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

scientific article published on June 2002

AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination

scientific article

Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice

scholarly article

Activation‐Induced Cytidine Deaminase Links Class Switch Recombination and Somatic Hypermutation ⬇️

scientific article published on April 1, 2003

Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes

scientific article published on 25 June 2009

Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation

scientific article published on 13 February 2019

Constitutive expression of AID leads to tumorigenesis

scientific article published on May 2003

Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.

scientific article published on February 2007

Glucocorticoids potentiate the inhibitory capacity of programmed cell death 1 by up-regulating its expression on T cells

scientific article published on 13 November 2019

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

scientific article published on 01 April 2007

Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation

scientific article

Identification of QTLs that modify peripheral neuropathy in NOD.H2b-Pdcd1-/- mice

scientific article published on 4 March 2009

LAG-3 inhibits the activation of CD4 T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII

scientific article published on 22 October 2018

LAG-3: from molecular functions to clinical applications

scientific article published on 01 September 2020

Molecular mechanism for generation of antibody memory

scientific article published on March 2009

Negative regulation of activation-induced cytidine deaminase in B cells

scholarly article

Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

scientific article

PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

scientific article

PD-1 deficiency results in the development of fatal myocarditis in MRL mice

article

Regulation of AID function in vivo

scientific article published on January 2007

Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses

scientific article published on 18 April 2019

Role of AID in tumorigenesis

scientific article published on January 2007

TRIM28 prevents autoinflammatory T cell development in vivo.

scientific article published on 29 April 2012

The AID enzyme induces class switch recombination in fibroblasts

scientific article published on 3 March 2002

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