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List of works by Roman Sommer

A biophysical study with carbohydrate derivatives explains the molecular basis of monosaccharide selectivity of the Pseudomonas aeruginosa lectin LecB

scientific article

Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors

scientific article published on 11 October 2019

Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis

scientific article published on 05 December 2019

Cinnamide Derivatives of d-Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa

scientific article

Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging

scientific article published on 28 September 2017

Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging

Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense

scientific article published in February 2018

Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa.

scientific article published on 4 August 2016

Development of a competitive binding assay for the Burkholderia cenocepacia lectin BC2L-A and structure activity relationship of natural and synthetic inhibitors

article

Glycomimetic, orally bioavailable LecB inhibitors block biofilm formation of Pseudomonas aeruginosa.

scientific article published on 22 December 2017

New approaches to control infections: anti-biofilm strategies against gram-negative bacteria.

scientific article published on January 2013

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections.

scientific article published on 23 January 2016

O-Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2-O-methyl-L-selenofucopyranoside

scientific article published on 22 December 2016

Synthesis of mannoheptose derivatives and their evaluation as inhibitors of the lectin LecB from the opportunistic pathogen Pseudomonas aeruginosa.

scientific article

The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery