List of works - Roberto Adachi

A 62-year-old man with shoulder pain

scientific article published on 01 August 2004

A dual-Ca2+-sensor model for neurotransmitter release in a central synapse

scientific article

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

scientific article

Atrial natriuretic peptide modulates alveolar type 2 cell adenylyl and guanylyl cyclases and inhibits surfactant secretion.

scientific article published in May 1998

Bronchoscopic Laser Interstitial Thermal Therapy: An Experimental Study in Normal Porcine Lung Parenchyma

scientific article published on 01 October 2018

Ca(2+) and calmodulin initiate all forms of endocytosis during depolarization at a nerve terminal.

scientific article published on 26 July 2009

Calmodulin binding to the C-terminus of the small-conductance Ca2+-activated K+ channel hSK1 is affected by alternative splicing

scientific article (publication date: 13 March 2001)

Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements

scientific article

Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses

scientific article

Compound vesicle fusion increases quantal size and potentiates synaptic transmission

scientific article

Essential role for mast cell tryptase in acute experimental colitis

scientific article

Expression and transcriptional regulation of Munc18 isoforms in mast cells

scientific article

Inhaled corticosteroids stabilize constrictive bronchiolitis after hematopoietic stem cell transplantation.

scientific article published on 15 October 2007

Lung epithelial cells are essential effectors of inducible resistance to pneumonia

scientific article published on May 2013

Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen

scientific article published on 10 January 2012

Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation

scientific article published on 14 April 2011

Mast cell-restricted tryptases: structure and function in inflammation and pathogen defense.

scientific article published on 15 May 2007

Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens

scientific article published on 24 June 2013

Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes

scientific article published on January 2009

Muc5b is required for airway defence

scientific journal article

Munc13 proteins control regulated exocytosis in mast cells

scientific article published on 15 November 2017

Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle regulated exocytosis in mast cells

scientific article published on 29 March 2018

Munc18-2, but not Munc18-1 or Munc18-3, regulates platelet exocytosis, hemostasis, and thrombosis

scientific article published on 29 January 2019

Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

scientific journal article

Platelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation.

scientific article published on 19 April 2018

Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity

scientific article published on June 2007

Rab3D, a small GTPase, is localized on mast cell secretory granules and translocates to the plasma membrane upon exocytosis.

scientific article

Signal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity.

scientific article

Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice

scientific article published on 3 April 2008

Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum.

scientific article published on 10 February 2009

Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells

scientific article

Synaptotagmin-2 controls regulated exocytosis but not other secretory responses of mast cells

scientific article published on 27 May 2009

Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses

scientific article

The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.

scientific article published on 16 November 2007

The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.

scientific article

The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections

scientific article published on 23 April 2007

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis.

scientific article

List of works by Roberto Adachi

A 62-year-old man with shoulder pain

A dual-Ca2+-sensor model for neurotransmitter release in a central synapse

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

Atrial natriuretic peptide modulates alveolar type 2 cell adenylyl and guanylyl cyclases and inhibits surfactant secretion.

Bronchoscopic Laser Interstitial Thermal Therapy: An Experimental Study in Normal Porcine Lung Parenchyma

Ca(2+) and calmodulin initiate all forms of endocytosis during depolarization at a nerve terminal.

Calmodulin binding to the C-terminus of the small-conductance Ca2+-activated K+ channel hSK1 is affected by alternative splicing

Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements

Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses

Compound vesicle fusion increases quantal size and potentiates synaptic transmission

Essential role for mast cell tryptase in acute experimental colitis

Expression and transcriptional regulation of Munc18 isoforms in mast cells

Inhaled corticosteroids stabilize constrictive bronchiolitis after hematopoietic stem cell transplantation.

Lung epithelial cells are essential effectors of inducible resistance to pneumonia

Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen

Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation

Mast cell-restricted tryptases: structure and function in inflammation and pathogen defense.

Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens

Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes

Muc5b is required for airway defence

Munc13 proteins control regulated exocytosis in mast cells

Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle regulated exocytosis in mast cells

Munc18-2, but not Munc18-1 or Munc18-3, regulates platelet exocytosis, hemostasis, and thrombosis

Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

Platelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation.

Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity

Rab3D, a small GTPase, is localized on mast cell secretory granules and translocates to the plasma membrane upon exocytosis.

Signal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity.

Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice

Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum.

Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells

Synaptotagmin-2 controls regulated exocytosis but not other secretory responses of mast cells

Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses

The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.

The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.

The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis.