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List of works by Adam S Adler

A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library.

scientific article published on 29 January 2018

A transcriptional program mediating entry into cellular quiescence

scientific article

Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR

scientific article published on 02 August 2020

An integrated genomic screen identifies LDHB as an essential gene for triple-negative breast cancer.

scientific article

Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics

scientific article published on 21 March 2019

CDK8 maintains tumor dedifferentiation and embryonic stem cell pluripotency.

scientific article

Decoding global gene expression programs in liver cancer by noninvasive imaging

scientific article

G1 arrest and differentiation can occur independently of Rb family function ⬇️

scientific article published on November 8, 2010

Generation of recombinant hyperimmune globulins from diverse B-cell repertoires

scientific article published on 15 April 2021

Genetic regulators of large-scale transcriptional signatures in cancer

scientific article

Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes

scientific article

Lactate dehydrogenase B is required for the growth of KRAS-dependent lung adenocarcinomas.

scientific article published on 6 December 2012

MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species

scientific article published on 01 July 2006

Massively parallel interrogation and mining of natively paired human TCRαβ repertoires

scientific article published on 16 March 2020

Molecular framework for response to imatinib mesylate in systemic sclerosis.

scientific article published on February 2009

Motif module map reveals enforcement of aging by continual NF-kappaB activity

scientific article

Predicting antibody binders and generating synthetic antibodies using deep learning

publication published on 01 January 2022

Preferential Identification of Agonistic OX40 Antibodies by Using Cell Lysate to Pan Natively Paired, Humanized Mouse-Derived Yeast Surface Display Libraries

scientific article published on 19 February 2019

Rare, high-affinity anti-pathogen antibodies from human repertoires, discovered using microfluidics and molecular genomics

scientific article published on 28 August 2017

Rare, high-affinity mouse anti-PD-1 antibodies that function in checkpoint blockade, discovered using microfluidics and molecular genomics.

scientific article published on 28 August 2017

Revealing targeted therapy for human cancer by gene module maps.

scientific article

Reversal of aging by NFkappaB blockade

scientific article published on 26 December 2007

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

scientific article

Single-cell transcriptomics reveals the effect of PD-L1/TGF-β blockade on the tumor microenvironment

scientific article published on 25 May 2021

Systematic functional characterization of cis-regulatory motifs in human core promoters

scientific article published on 6 February 2008

The Rsp5 ubiquitin ligase binds to and ubiquitinates members of the yeast CIN85-endophilin complex, Sla1-Rvs167.

scientific article

The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression

scientific article

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