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List of works by Hamish D Toop

A fluorescent assay for ceramide synthase activity.

scientific article published on June 2012

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

scientific article published in Nature Communications

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

scientific article published on 18 June 2016

Concise Total Synthesis of Dioncophylline E through an ortho-Arylation Strategy

scientific article

Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.

scientific article

Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia

scientific article published on 01 May 2016

MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity.

scientific article published on 13 March 2015

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

scientific article published in Nature Communications

Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A.

scientific article

Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia

scientific article published on 08 April 2020

Synthesis and biological evaluation of analogs of AAL(S) for use as ceramide synthase 1 inhibitors

scientific article published on 04 November 2015

Tumor necrosis factor-related apoptosis-inducing ligand regulates hallmark features of airways remodeling in allergic airways disease

scientific article published on 01 July 2014

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