List of works - Mirco Schmolke

17β-estradiol protects primary macrophages against HIV infection through induction of interferon-alpha

scientific article

A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.

scientific article published on 30 July 2014

A single respiratory tract infection early in life reroutes healthy microbiome development and affects adult metabolism in a preclinical animal model

scientific article published in 2022

Author Correction: Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

scientific article published on 16 June 2020

Avian influenza A H10N8--a virus on the verge?

scientific article published on 5 February 2014

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

scientific article published on 11 September 2011

Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

scientific article

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species

scientific article

Divergent H7 immunogens offer protection from H7N9 virus challenge.

scientific article

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

scientific article

Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome

scientific article published on 28 September 2009

Evasion of innate and adaptive immune responses by influenza A virus

scientific article

Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein

scientific article (publication date: May 2015)

H5N1 influenza A virus PB1-F2 relieves HAX-1-mediated restriction of avian virus polymerase PA in human lung cells.

scientific article published on 21 March 2018

H5N1 virus activates signaling pathways in human endothelial cells resulting in a specific imbalanced inflammatory response

scientific article published on 24 November 2010

High level expression of the anti-retroviral protein APOBEC3G is induced by influenza A virus but does not confer antiviral activity

scientific article published on 16 April 2009

Highly pathogenic influenza viruses inhibit inflammatory response in monocytes via activation of rar-related orphan receptor RORα.

scientific article published on 22 February 2013

Host modulators of H1N1 cytopathogenicity

scientific article

Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses.

scientific article

Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein

scientific article

Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

scientific article

Influenza A Virus Genetic Tools: From Clinical Sample to Molecular Clone

scientific article published on 01 January 2018

Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

scientific article published on 17 January 2007

Influenza A virus exploits transferrin receptor recycling to enter host cells

scientific article published on 23 May 2023

Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis.

scientific article published on 10 January 2018

Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression

scientific article

Influenza A viruses limit NLRP3-NEK7-complex formation and pyroptosis in human macrophages

scientific article published on 12 November 2020

Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility.

scientific article published on January 2013

Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction.

scientific article published on 7 March 2012

Inhibition of p38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H5N1 infection

scientific article

Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export

scientific article published on February 2012

MEK5/ERK5 signaling modulates endothelial cell migration and focal contact turnover

scientific article published on 15 July 2009

Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

scientific article published on 21 May 2020

Microbiome disturbance and resilience dynamics of the upper respiratory tract in response to influenza A virus infection in analog hosts

article

Model of influenza A virus infection: dynamics of viral antagonism and innate immune response.

scientific article

Ménage à trois: Virus, Host, and Microbiota in Experimental Infection Models

scientific article published on 09 January 2019

NS-based live attenuated H1N1 pandemic vaccines protect mice and ferrets

scientific article

PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models

scientific article

Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target

scientific article published in Nature Communications

Polyethylenimine, a cost-effective transfection reagent

scholarly article by Christina Ehrhardt published in June 2006

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection

scientific article

RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection

scientific article published on April 2014

Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization

scientific article published on 08 December 2020

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein

scientific article

The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA.

scientific article

The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice

scientific article

List of works by Mirco Schmolke

17β-estradiol protects primary macrophages against HIV infection through induction of interferon-alpha

A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.

A single respiratory tract infection early in life reroutes healthy microbiome development and affects adult metabolism in a preclinical animal model

Author Correction: Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

Avian influenza A H10N8--a virus on the verge?

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species

Divergent H7 immunogens offer protection from H7N9 virus challenge.

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome

Evasion of innate and adaptive immune responses by influenza A virus

Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein

H5N1 influenza A virus PB1-F2 relieves HAX-1-mediated restriction of avian virus polymerase PA in human lung cells.

H5N1 virus activates signaling pathways in human endothelial cells resulting in a specific imbalanced inflammatory response

High level expression of the anti-retroviral protein APOBEC3G is induced by influenza A virus but does not confer antiviral activity

Highly pathogenic influenza viruses inhibit inflammatory response in monocytes via activation of rar-related orphan receptor RORα.

Host modulators of H1N1 cytopathogenicity

Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses.

Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein

Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

Influenza A Virus Genetic Tools: From Clinical Sample to Molecular Clone

Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

Influenza A virus exploits transferrin receptor recycling to enter host cells

Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis.

Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression

Influenza A viruses limit NLRP3-NEK7-complex formation and pyroptosis in human macrophages

Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility.

Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction.

Inhibition of p38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H5N1 infection

Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export

MEK5/ERK5 signaling modulates endothelial cell migration and focal contact turnover

Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

Microbiome disturbance and resilience dynamics of the upper respiratory tract in response to influenza A virus infection in analog hosts

Model of influenza A virus infection: dynamics of viral antagonism and innate immune response.

Ménage à trois: Virus, Host, and Microbiota in Experimental Infection Models

NS-based live attenuated H1N1 pandemic vaccines protect mice and ferrets

PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models

Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target

Polyethylenimine, a cost-effective transfection reagent

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection

RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection

Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein

The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA.

The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice