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List of works by William Brown

A structurally defined mini-chromosome vector for the mouse germ line.

scientific article

Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome

scientific article

An unpaired mouse centromere passes consistently through male meiosis and does not significantly compromise spermatogenesis.

scientific article published on 8 November 2003

CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1.

scientific article

CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells.

scientific article

Centromere activation.

scientific article published on September 1995

Characterization of chicken CENP-A and comparative sequence analysis of vertebrate centromere-specific histone H3-like proteins.

scientific article published on October 2003

Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes.

scientific article

Comparative functional genomics of the fission yeasts

scientific article

Comparison and optimization of ten phage encoded serine integrases for genome engineering in Saccharomyces cerevisiae

scientific article published on 9 February 2016

Comparison of Dam tagging and chromatin immunoprecipitation as tools for the identification of the binding sites for S. pombe CENP-C.

scientific article published in January 2005

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

scientific article

Human mini-chromosomes in mouse embryonal stem cells.

scientific article published on August 1997

Hypervariable telomeric sequences from the human sex chromosomes are pseudoautosomal

scientific article published in Nature

Iterative in vivo assembly of large and complex transgenes by combining the activities of phiC31 integrase and Cre recombinase.

scientific article

Kinetochore assembly and heterochromatin formation occur autonomously in Schizosaccharomyces pombe

scientific article published on 21 January 2014

Molecular cloning of human telomeres in yeast.

scientific article published in April 1989

Mutation and selection explain why many eukaryotic centromeric DNA sequences are often A + T rich

scientific article published on 01 January 2022

Rearranging the centromere of the human Y chromosome with phiC31 integrase

scientific article

Reorganization of the Growth Pattern of Schizosaccharomyces pombe in Invasive Filament Formation

scientific article published on September 24, 2010

Serine recombinases as tools for genome engineering.

scientific article published on 30 December 2010

Site-specific recombination by phiC31 integrase and other large serine recombinases.

scientific article published on April 2010

Site-specific recombination in Schizosaccharomyces pombe and systematic assembly of a 400kb transgene array in mammalian cells using the integrase of Streptomyces phage phiBT1.

scientific article published on 20 December 2007

Stable length polymorphism of up to 260 kb at the tip of the short arm of human chromosome 16

article

Targeted breakage of a human chromosome mediated by cloned human telomeric DNA

scientific article published on December 1, 1992

Telomerase and chromosome healing

scientific article published on 01 March 1992

The chicken HPRT gene: a counter selectable marker for the DT40 cell line.

scientific article published on May 1999

The chicken as a model for large-scale analysis of vertebrate gene function.

scientific article

The genomic and phenotypic diversity of Schizosaccharomyces pombe

scientific article published on 9 February 2015

The sequence organization of the long arm pseudoautosomal region of the human sex chromosomes.

scientific article published in May 1994

Unsuccessful attempt at gene-editing by homologous recombination in the zebrafish germ line using the approach of "Rong and Golic".

scientific article published on 21 March 2012