List of works by Claus Kristensen

A new secreted insect protein belonging to the immunoglobulin superfamily binds insulin and related peptides and inhibits their activities.

scientific article published on June 2000

A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution

Alanine scanning mutagenesis of insulin

scientific article published on 01 May 1997

Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use

scientific article published on 01 June 2000

Deep sequencing reveals different compositions of mRNA transcribed from the F8 gene in a panel of FVIII-producing CHO cell lines.

scientific article published on 26 May 2015

Dimeric fragment of the insulin receptor alpha-subunit binds insulin with full holoreceptor affinity.

scientific article published on 12 January 2001

Engineered CHO cells for production of diverse, homogeneous glycoproteins.

scientific article published on 20 July 2015

Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor.

scientific article

Functional reconstitution of insulin receptor binding site from non-binding receptor fragments

scientific article

Glycoengineering design options for IgG1 in CHO cells using precise gene editing.

scientific article published on 27 March 2018

Ligand-induced conformational change in the minimized insulin receptor

scientific article published on 01 October 2000

N-glycosylation increases the circulatory half-life of human growth hormone

scientific article published on 8 September 2010

Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data

scientific article

Platform process for production of monoclonal antibodies for research purposes - improvement option

scientific article

Posttranslational N-glycosylation takes place during the normal processing of human coagulation factor VII.

scientific article

Role of insulin receptor dimerization domains in ligand binding, cooperativity, and modulation by anti-receptor antibodies

scientific article published in March 2002

Sequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy

scientific article published on 8 March 2015

Specificity of insulin and insulin-like growth factor I receptors investigated using chimeric mini-receptors. Role of C-terminal of receptor alpha subunit

scientific article published on 01 December 1999

Structural basis of the aberrant receptor binding properties of hagfish and lamprey insulins.

scientific article published on December 2009

Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

scientific article published in Nature Communications

Toward genome-scale models of the Chinese hamster ovary cells: incentives, status and perspectives

article