List of works - Armand Valsesia

A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

scientific article published on 03 June 2020

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.

scientific article

Accurate and reliable high-throughput detection of copy number variation in the human genome

scientific article

Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study.

scientific article published on 2 April 2018

AssociationViewer: a scalable and integrated software tool for visualization of large-scale variation data in genomic context

scientific article

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

scientific article published on 22 September 2020

Breaking the waves: improved detection of copy number variation from microarray-based comparative genomic hybridization.

scientific article

Copy Number Variation

scientific article published on 01 January 2018

Corrigendum: Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

scholarly article published in Nature Genetics

Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism.

scientific article

Distinct lipid profiles predict improved glycemic control in obese, nondiabetic patients after a low-caloric diet intervention: the Diet, Obesity and Genes randomized trial

scientific article

Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage

scientific article published on 20 September 2019

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.

scientific article

FADS1 genotype is distinguished by human subcutaneous adipose tissue fatty acids, but not inflammatory gene expression

article

GH deficiency status combined with GH receptor polymorphism affects response to GH in children

scientific article

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

scientific article published on 15 August 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Global variation in copy number in the human genome

scientific article

Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort

scientific article

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

scientific article

Molecular Biomarkers for Weight Control in Obese Individuals Subjected to a Multiphase Dietary Intervention.

scientific article published on 5 May 2017

Multiple hot-deck imputation for network inference from RNA sequencing data

scientific article

Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance

scientific article

Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma

scientific article

Obesity shows preserved plasma proteome in large independent clinical cohorts

scientific article published in Scientific Reports

Origins and functional impact of copy number variation in the human genome

scientific article (publication date: April 2010)

Plasma lipid profiling of tissue-specific insulin resistance in human obesity

scientific article published on 21 September 2018

Plasma metabolites and lipids predict insulin sensitivity improvement in obese, nondiabetic individuals after a 2-phase dietary intervention

scientific article published on 01 July 2018

Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator

scientific article published on 12 December 2017

Proteomic Biomarker Discovery in 1000 Human Plasma Samples with Mass Spectrometry.

scientific article published on December 2015

Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity

scientific article

Rational and design of an overfeeding protocol in constitutional thinness: Understanding the physiology, metabolism and genetic background of resistance to weight gain.

scientific article published on 13 July 2016

Sexual Dimorphism, Age, and Fat Mass Are Key Phenotypic Drivers of Proteomic Signatures

scientific article

Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans

scientific article published on 06 September 2019

The Growing Importance of CNVs: New Insights for Detection and Clinical Interpretation

scientific article (publication date: 2013)

The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome.

scientific article

Transcriptome profiling from adipose tissue during a low-calorie diet reveals predictors of weight and glycemic outcomes in obese, nondiabetic subjects

scientific article published on 9 August 2017

List of works by Armand Valsesia

A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.

Accurate and reliable high-throughput detection of copy number variation in the human genome

Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study.

AssociationViewer: a scalable and integrated software tool for visualization of large-scale variation data in genomic context

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Breaking the waves: improved detection of copy number variation from microarray-based comparative genomic hybridization.

Copy Number Variation

Corrigendum: Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism.

Distinct lipid profiles predict improved glycemic control in obese, nondiabetic patients after a low-caloric diet intervention: the Diet, Obesity and Genes randomized trial

Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.

FADS1 genotype is distinguished by human subcutaneous adipose tissue fatty acids, but not inflammatory gene expression

GH deficiency status combined with GH receptor polymorphism affects response to GH in children

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Genome-wide meta-analysis of common variant differences between men and women

Global variation in copy number in the human genome

Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

Molecular Biomarkers for Weight Control in Obese Individuals Subjected to a Multiphase Dietary Intervention.

Multiple hot-deck imputation for network inference from RNA sequencing data

Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance

Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma

Obesity shows preserved plasma proteome in large independent clinical cohorts

Origins and functional impact of copy number variation in the human genome

Plasma lipid profiling of tissue-specific insulin resistance in human obesity

Plasma metabolites and lipids predict insulin sensitivity improvement in obese, nondiabetic individuals after a 2-phase dietary intervention

Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator

Proteomic Biomarker Discovery in 1000 Human Plasma Samples with Mass Spectrometry.

Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity

Rational and design of an overfeeding protocol in constitutional thinness: Understanding the physiology, metabolism and genetic background of resistance to weight gain.

Sexual Dimorphism, Age, and Fat Mass Are Key Phenotypic Drivers of Proteomic Signatures

Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans

The Growing Importance of CNVs: New Insights for Detection and Clinical Interpretation

The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome.

Transcriptome profiling from adipose tissue during a low-calorie diet reveals predictors of weight and glycemic outcomes in obese, nondiabetic subjects