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List of works by Yushi Futamura

A new peptaibol, RK-026A, from the soil fungus Trichoderma sp. RK10-F026 by culture condition-dependent screening ⬇️

A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition

scientific article published on 23 March 2019

Alkyldihydropyrones, new polyketides synthesized by a type III polyketide synthase from Streptomyces reveromyceticus. ⬇️

scientific article

Amino-group carrier-protein-mediated secondary metabolite biosynthesis in Streptomyces

scientific article published on 26 September 2016

An overproduction of astellolides induced by genetic disruption of chromatin-remodeling factors in Aspergillus oryzae.

scientific article published on July 2015

Bioenergetic and proteomic profiling to screen small molecule inhibitors that target cancer metabolisms

scientific article published on 06 June 2018

Catalytic Enantioselective Synthesis of a Pyrrolizidine-Alkaloid-Inspired Compound Collection with Antiplasmodial Activity

scientific article published on 20 February 2018

Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide.

scientific article published on 9 February 2018

Construction of a potato fraction library for the investigation of functional secondary metabolites

scientific article published on 05 October 2018

Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I.

scientific article

High-throughput screening identifies artesunate as selective inhibitor of cancer stemness: Involvement of mitochondrial metabolism.

scientific article

Hitoyol A and B, Two Norsesquiterpenoids from the Basidiomycete Coprinopsis cinerea

scientific article published on 20 July 2017

Identification of a molecular target of a novel fungal metabolite, pyrrolizilactone, by phenotypic profiling systems

scientific article

Identification of small molecule inhibitors of p27(Kip1) ubiquitination by high-throughput screening.

scientific article

Inhibition of mitochondrial complex I by the novel compound FSL0260 enhances high salinity-stress tolerance in Arabidopsis thaliana

scientific article published on 26 May 2020

Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase.

scientific article published on 21 March 2016

Kinanthraquinone, a new anthraquinone carboxamide isolated from Streptomyces reveromyceticus SN-593-44. ⬇️

scientific article published on 6 February 2018

Methyl 3-((6-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)amino)benzoate (GN39482) as a tubulin polymerization inhibitor identified by MorphoBase and ChemProteoBase profiling methods.

scientific article published on 11 May 2015

Mitochondrial uncoupler exerts a synthetic lethal effect against β-catenin mutant tumor cells

scientific article

Morphobase, an encyclopedic cell morphology database, and its use for drug target identification.

scientific article

New Cyclic Lipopeptides of the Iturin Class Produced by Saltern-Derived Bacillus sp. KCB14S006. ⬇️

scientific article published on 2 April 2016

Octaminomycins A and B, Cyclic Octadepsipeptides Active against Plasmodium falciparum.

scientific article

Opantimycin A, a new metabolite isolated from Streptomyces sp. RK88-1355 ⬇️

scientific article published on 07 September 2016

Phenotypic screening meets natural products in drug discovery.

scientific article published in January 2017

Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival

scientific article (publication date: 23 May 2016)

Proteomic profiling reveals that collismycin A is an iron chelator.

scientific article published on 6 December 2016

Pyrrolizilactone, a new pyrrolizidinone metabolite produced by a fungus.

scientific article published on 29 May 2013

RK-144171, a new benadrostin derivative produced by Streptomyces sp. RK88-1441

scientific article published on 08 June 2016

RK-270A-C, new oxindole derivatives isolated from a microbial metabolites fraction library of Streptomyces sp. RK85-270. ⬇️

scientific article

Structures and biological activities of azaphilones produced by Penicillium sp. KCB11A109 from a ginseng field

scientific article published in February 2016

Synthesis and biological activity of 5-(4-methoxyphenyl)-oxazole derivatives.

scientific article

Target identification of small molecules based on chemical biology approaches ⬇️

scientific article published on May 1, 2013

Trachyspic acid 19-butyl ester, a new inhibitor of Plk1 polo box domain-dependent recognition from uncharacterized fungus RKGS-F2684

scientific article published on 18 January 2017

Two new triterpenoids from the roots of Pinus densiflora

scientific article published on 02 December 2016

Unantimycin A, a new neoantimycin analog isolated from a microbial metabolite fraction library ⬇️

scientific article published on 9 December 2015

Vipirinin, a coumarin-based HIV-1 Vpr inhibitor, interacts with a hydrophobic region of VPR.

scientific article

Wakodecalines A and B, new decaline metabolites isolated from a fungus Pyrenochaetopsis sp. RK10-F058.

scientific article

Zealpeptaibolin, an 11-mer cytotoxic peptaibol group with 3 Aib-Pro motifs isolated from Trichoderma sp. RK10-F026

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