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List of works by Stephen J Smerdon

1H, 15N and 13C assignments of the DNA binding domain of transcription factor Mbp1 from S. cerevisiae in both its free and the DNA bound forms, and 1H assignments of the free DNA

scientific article published on 01 April 1999

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint

scientific article

A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage

scientific article

A unified polymerase mechanism for nonhomologous DNA and RNA polymerases

scientific article published on 01 December 1994

A year in structural signaling: mTOR--the PIKK of the bunch?

scientific article published on 04 March 2014

Access to phosphoproteins and glycoproteins through semi-synthesis, Native Chemical Ligation and N→S acyl transfer

scientific article published on 9 September 2010

Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes

scientific article

An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice

scientific article

An attenuated mutant of the Rv1747 ATP-binding cassette transporter of Mycobacterium tuberculosis and a mutant of its cognate kinase, PknF, show increased expression of the efflux pump-related iniBAC operon

scientific article published on 23 August 2013

An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis

scientific article

An undecided coiled coil: the leucine zipper of Nek2 kinase exhibits atypical conformational exchange dynamics

scientific article

Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein

scientific article published on 18 October 2011

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response

scientific article

Characterization of the DNA-binding domains from the yeast cell-cycle transcription factors Mbp1 and Swi4.

scientific article published on April 2000

Chk2 oligomerization studied by phosphopeptide ligation: implications for regulation and phosphodependent interactions

scientific article

Clb6/Cdc28 and Cdc14 regulate phosphorylation status and cellular localization of Swi6

scientific article

Comment on "The Pentacovalent Phosphorus Intermediate of a Phosphoryl Transfer Reaction"

scientific article published on 01 August 2003

Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion

article

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

scientific article

Crystallization and preliminary X-ray diffraction studies on the N-utilizing substance-B (NusB) from Mycobacterium tuberculosis

scientific article published on 01 January 2000

Effective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents

scientific article

Expression, purification, and crystallization of the DNA-binding domain from the Saccharomyces cerevisae cell-cycle transcription factor MBP-1

scientific article published on 01 February 1997

FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain

scientific article

Forkhead-associated (FHA) domain containing ABC transporter Rv1747 is positively regulated by Ser/Thr phosphorylation in Mycobacterium tuberculosis

scientific article

Function of the nucleotide exchange activity of vav1 in T cell development and activation

scientific article

GTPase-activating proteins and their complexes.

scientific article published in April 1998

HF-Free Boc Synthesis of Peptide Thioesters for Ligation and Cyclization

scientific article published on 21 September 2016

High-resolution structure of a retroviral capsid hexameric amino-terminal domain

scientific article

Human HMG box transcription factor HBP1: a role in hCD2 LCR function

scientific article

Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis

scientific article published on December 2008

Interactions among residues CD3, E7, E10, and E11 in myoglobins: attempts to simulate the ligand-binding properties of Aplysia myoglobin

scientific article

IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases

scientific article

KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity

scientific article published in 2022

Key features of the interaction between Pcf11 CID and RNA polymerase II CTD.

scientific article published on 16 January 2005

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

scientific article

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex

scientific article published on 24 April 2017

Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface

scientific article

MgF(3)(-) as a transition state analog of phosphoryl transfer

scientific article

Molecular basis of phosphorylation-induced activation of the NADPH oxidase

scientific article (publication date: 2 May 2003)

NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

scientific article

NMR structure of the DNA-binding domain of the cell cycle protein Mbp1 from Saccharomyces cerevisiae

scientific article (publication date: 11 February 2003)

Pellino Proteins Splitting Up the FHAmily!

scientific article published on 01 December 2008

PhosphoSerine/threonine binding domains: you can't pSERious?

scientific article

Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex

scientific article

Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair

scientific article published on February 2012

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1

scientific article published on 01 March 2022

Serine92 (F7) contributes to the control of heme reactivity and stability in myoglobin.

scientific article

Signaling by the sea.

scientific article published in August 2004

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling

scientific article

Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

scientific article

Structural and functional analysis of phosphothreonine-dependent FHA domain interactions

scientific article

Structural and functional architecture of the yeast cell-cycle transcription factor swi6 1 1Edited by K. Nagai ⬇️

scientific article published on September 4, 1998

Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2

scientific article

Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms

scientific article

Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer

scientific article

Structure and regulation of the human Nek2 centrosomal kinase

scientific article

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

scientific article

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

scientific article

Structure of the amino-terminal domain from the cell-cycle regulator Swi6

scientific article

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1

scientific article

Structure of the complex of calmodulin with the target sequence of calmodulin-dependent protein kinase I: studies of the kinase activation mechanism

scientific article

Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors

scientific article

Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis

scientific article

Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module

scientific article

The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage

scientific article published on 27 July 2014

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity ⬇️

scientific article (publication date: 26 December 1997)

The X-ray structure of the DNA-binding domain from the Saccharomyces cerevisiae cell-cycle transcription factor Mbp1 at 2.1 Å resolution 1 1Edited by J. Karn ⬇️

scientific article published on September 12, 1997

The crystal structure of NusB from Mycobacterium tuberculosis

scientific article published in June 2000

The influence of DNA binding on the backbone dynamics of the yeast cell-cycle protein Mbp1

scientific article published on 01 March 2000

The mechanism of autooxidation of myoglobin

scientific article published on 01 April 1993

The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain

scientific article

The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator

scientific article

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

scientific article

The stimulatory RNA of the Visna-Maedi retrovirus ribosomal frameshifting signal is an unusual pseudoknot with an interstem element

scientific article published on 21 May 2008

The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways

scientific article

The use of in vitro peptide-library screens in the analysis of phosphoserine/threonine-binding domain structure and function

scientific article

Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex

scientific article published on December 2016

Two DNA Polymerases: HIV Reverse Transcriptase and the Klenow Fragment of Escherichia coli DNA Polymerase I

scientific article published on 01 January 1993

Uncoupling conformational states from activity in an allosteric enzyme

scientific article published on 07 August 2017

Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains

scientific article published on 23 October 2015

X-ray structural analysis of the yeast cell cycle regulator Swi6 reveals variations of the ankyrin fold and has implications for Swi6 function

scientific article

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