List of works - Sandeep Chhabra

15N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins

scientific article published on 5 February 2018

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.

scientific article published on 24 November 2017

A Naturally Occurring Peptide with an Elementary Single Disulfide-Directed β-Hairpin Fold

scientific article published on 2 February 2016

A novel inhibitor of α9α10 nicotinic acetylcholine receptors from Conus vexillum delineates a new conotoxin superfamily.

scientific article

A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

scientific article

A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

scientific article

A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent

scientific article published on 06 August 2014

An iminodiacetic acid based lanthanide binding tag for paramagnetic exchange NMR spectroscopy

scientific article published on 07 April 2011

Aromatic 19F-13C TROSY: a background-free approach to probe biomolecular structure, function, and dynamics

scientific article published on 11 March 2019

CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T Cell Activation.

scientific article published on 3 November 2017

Conformational flexibility in the binding surface of the potassium channel blocker ShK.

scientific article

Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

scientific article published on 30 April 2010

DOTA-Amide Lanthanide Tag for Reliable Generation of Pseudocontact Shifts in Protein NMR Spectra

article

Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets

scientific article

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

scientific article published on 16 June 2017

Engineering of a bis-chelator motif into a protein α-helix for rigid lanthanide binding and paramagnetic NMR spectroscopy

article

Exploration of rate-limiting conformational state for 5-[(7-chloro-4-quinolinyl)amino]-3-[(alkylamino)methyl][1,1'-biphenyl]-2-ols and N(omega)-oxides (tebuquine analogues) for antimalarial activity using molecular shape analysis and molecular field

scientific article published on 11 April 2007

Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK

scientific article

Installation of a Rigid EDTA-Like Motif into a Protein α-Helix for Paramagnetic NMR Spectroscopy with Cobalt(II) Ions.

scientific article published on 4 December 2015

Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin BuIIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3.

scientific article

Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

scientific article

N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.

scientific article published on 23 April 2015

Reinvestigation of the biological activity of d-allo-ShK protein

scientific article published on 8 June 2017

Stereoselective synthesis and structural elucidation of dicarba peptides

scientific article published on 01 March 2016

Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ.

scientific article published on 27 January 2016

Structure and activity of contryphan-Vc2: Importance of the d-amino acid residue.

scientific article published on 16 February 2017

Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor ⬇️

scientific article published on January 19, 2012

Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus

scientific article

VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins

scientific article

List of works by Sandeep Chhabra

15N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.

A Naturally Occurring Peptide with an Elementary Single Disulfide-Directed β-Hairpin Fold

A novel inhibitor of α9α10 nicotinic acetylcholine receptors from Conus vexillum delineates a new conotoxin superfamily.

A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent

An iminodiacetic acid based lanthanide binding tag for paramagnetic exchange NMR spectroscopy

Aromatic 19F-13C TROSY: a background-free approach to probe biomolecular structure, function, and dynamics

CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T Cell Activation.

Conformational flexibility in the binding surface of the potassium channel blocker ShK.

Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

DOTA-Amide Lanthanide Tag for Reliable Generation of Pseudocontact Shifts in Protein NMR Spectra

Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

Engineering of a bis-chelator motif into a protein α-helix for rigid lanthanide binding and paramagnetic NMR spectroscopy

Exploration of rate-limiting conformational state for 5-[(7-chloro-4-quinolinyl)amino]-3-[(alkylamino)methyl][1,1'-biphenyl]-2-ols and N(omega)-oxides (tebuquine analogues) for antimalarial activity using molecular shape analysis and molecular field

Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK

Installation of a Rigid EDTA-Like Motif into a Protein α-Helix for Paramagnetic NMR Spectroscopy with Cobalt(II) Ions.

Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin BuIIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3.

Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.

Reinvestigation of the biological activity of d-allo-ShK protein

Stereoselective synthesis and structural elucidation of dicarba peptides

Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ.

Structure and activity of contryphan-Vc2: Importance of the d-amino acid residue.

Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor ⬇️

Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus

VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins