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List of works by Wim Versées

1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors

scientific article published on 09 February 2007

A Single-Amino-Acid Substitution in Obg Activates a New Programmed Cell Death Pathway in Escherichia coli

scientific article published on 22 December 2015

A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax

scientific article

A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover ⬇️

scientific article published on 18 October 2017

A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance in Pseudomonas aeruginosa.

scientific article

A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations

scientific article published on 22 December 2020

Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE.

scientific article

Biochemical and kinetic properties of the complex Roco G-protein cycle

scientific article published on 01 November 2018

Biochemical determinants of ObgE-mediated persistence

scientific article published on 18 September 2019

Catalysis by nucleoside hydrolases

scientific article published on December 2003

Characterization of two homologous 2′-O-methyltransferases showing different specificities for their tRNA substrates

scientific article

Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors

scientific article

Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life

scientific article published in June 2012

Crystallization and preliminary X-ray crystallographic analysis of putative tRNA-modification enzymes fromPyrococcus furiosusandThermus thermophilus ⬇️

scientific article published on October 27, 2011

ELP3 controls active zone morphology by acetylating the ELKS family member Bruchpilot

scientific article

Elongator, a conserved multitasking complex?

scientific article published on 14 April 2010

Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax

scientific article

Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis

scientific article

Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras.

scientific article published on 13 October 2017

G-domain dimerization orchestrates the tRNA wobble modification reaction in the MnmE/GidA complex.

scientific article published on 8 July 2009

GTP Binding is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE

scientific article published on 18 December 2019

Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.

scientific article published on 2 February 2016

It takes two to rule translation elongation

scientific article published on 01 January 2015

Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase

scientific article

New insights into the mechanism of nucleoside hydrolases from the crystal structure of the Escherichia coli YbeK protein bound to the reaction product

scientific article published on January 2006

NrdH-redoxin of Mycobacterium tuberculosis and Corynebacterium glutamicum Dimerizes at High Protein Concentration and Exclusively Receives Electrons from Thioredoxin Reductase

scientific article

Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.

scientific article published on 4 June 2015

Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors. ⬇️

scientific article published on 14 March 2018

Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release.

scientific article published in November 2003

Roco Proteins: GTPases with a Baroque Structure and Mechanism ⬇️

scientific article published on 03 January 2019

SAXS analysis of the tRNA-modifying enzyme complex MnmE/MnmG reveals a novel interaction mode and GTP-induced oligomerization

scientific article

Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function

scientific article

Structural and biochemical analysis of Escherichia coli ObgE, a central regulator of bacterial persistence.

scientific article published on 21 February 2017

Structural and biochemical analysis of the dual-specificity Trm10 enzyme from Thermococcus kodakaraensis prompts reconsideration of its catalytic mechanism

scientific article published on 30 May 2018

Structural and biochemical characterization of the nucleoside hydrolase from C. elegans reveals the role of two active site cysteine residues in catalysis.

scientific article published on 20 February 2017

Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue

scientific article published on 15 December 2015

Structural and kinetic characterization of Trypanosoma congolense pyruvate kinase

scientific article published on 19 February 2020

Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin.

scientific article published on June 2006

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts

scientific journal article

Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei

scientific article

Structure and nucleotide-induced conformational dynamics of the Chlorobium tepidum Roco protein

scientific article published on 07 January 2019

Structure of an early native-like intermediate of β2-microglobulin amyloidogenesis

scientific article

Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF

scientific article published on 29 March 2016

Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage.

scientific article published on 28 January 2005

Synthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors.

scientific article published in February 2009

TBC1D24-TLDc-related epilepsy exercise-induced dystonia: rescue by antioxidants in a disease model

scientific article published on 01 August 2019

The Escherichia coli GTPase ObgE modulates hydroxyl radical levels in response to DNA replication fork arrest.

scientific article

The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.

scientific article

The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis

scientific article published on 15 June 2017

The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes

scientific article

The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism

scientific article

The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N²-methylguanosine at position 6 in tRNA.

scientific article published on 15 February 2012

The universally conserved prokaryotic GTPases

scientific article

Therapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system.

scientific article published in November 2005

Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis

scientific article published on 29 March 2006

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