Search filters

List of works by Tomasz Jurkowski

Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase.

scientific article

Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue.

scientific article

Bio-On-Magnetic-Beads (BOMB): Open platform for high-throughput nucleic acid extraction and manipulation

scientific article published on 10 January 2019

Bisulfite sequencing Data Presentation and Compilation (BDPC) web server--a useful tool for DNA methylation analysis.

scientific article

Burning off DNA Methylation: New Evidence for Oxygen-Dependent DNA Demethylation

article

CONTAIN: An open-source shipping container laboratory optimised for automated COVID-19 diagnostics

scientific article published on 21 May 2020

Capturing and Stabilizing Folded Proteins in Lattices Formed with Branched Oligonucleotide Hybrids

scientific article published on 10 June 2018

Conformation and activity of lipase B from Candida antarctica in bicontinuous microemulsions

scientific article published on 27 April 2015

Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences

scientific article published on 09 June 2015

DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution

scientific article

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase

scientific article published on 29 November 2016

Genome-wide hydroxymethylcytosine pattern changes in response to oxidative stress.

scientific article published on 4 August 2015

H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.

scientific article published on 12 December 2017

Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors.

scientific article published on 13 November 2017

Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism

scientific journal article

Investigation of the C-terminal domain of the bacterial DNA-(adenine N6)-methyltransferase CcrM.

scientific article

Mapping of protein-protein interaction sites by the 'absence of interference' approach.

scientific article

Mapping the tRNA binding site on the surface of human DNMT2 methyltransferase

scientific article published on 23 May 2012

Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation.

scientific article published on 27 May 2016

Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies

scientific article

Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase.

scientific article published on 30 January 2006

On the Evolutionary Origin of Eukaryotic DNA Methyltransferases and Dnmt2

scientific article published on November 30, 2011

Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling.

scientific article published on 15 October 2012

Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.

scientific article

Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms.

scientific article published on 11 October 2016

Somatic cancer mutations in the DNMT2 tRNA methyltransferase alter its catalytic properties

scientific article published on 05 March 2015

Structure and function of mammalian DNA methyltransferases.

scientific article

Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity

scientific article

Target recognition, RNA methylation activity and transcriptional regulation of the Dictyostelium discoideum Dnmt2-homologue (DnmA)

scientific article

Target specificity of mammalian DNA methylation and demethylation machinery

scientific article published on 21 December 2017

Targeted epigenetic editing of SPDEF reduces mucus production in lung epithelial cells.

scientific article published on 23 December 2016

The Caulobacter crescentus DNA-(adenine-N6)-methyltransferase CcrM methylates DNA in a distributive manner.

scientific article published on 16 September 2011

The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu

scientific article

The M.EcoRV DNA-(adenine N6)-methyltransferase uses DNA bending for recognition of an expanded EcoDam recognition site.

scientific article published on 31 October 2007

The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA.

scientific article