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List of works by José B Carvalheira

A central role for neuronal adenosine 5'-monophosphate-activated protein kinase in cancer-induced anorexia

scientific article published on 23 August 2007

A new role for the brain in metabolic control

scientific article published in May 2014

ADJUVANT CHEMORADIOTHERAPY AFTER SUBTOTAL OR TOTAL GASTRECTOMY AND D2 LIMPHADENECTOMY INCREASES SURVIVAL IN ADVANCED GASTRIC CANCER?

scientific article published on 20 December 2019

Acanthosis nigricans, tripe palms and the sign of Leser-Trelat in a patient with a benign hepatic neoplasia

scientific article published on 01 July 2007

Activation of AMPK in rat hypothalamus participates in cold-induced resistance to nutrient-dependent anorexigenic signals.

scientific article

Acute exercise induces a phenotypic switch in adipose tissue macrophage polarization in diet-induced obese rats.

scientific article published on 11 June 2013

Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats.

scientific article published in November 2007

Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.

scientific article

Analysis of the physical activity effects and measurement of pro-inflammatory cytokines in irradiated lungs in rats

scientific article published on 01 March 2012

Angiotensin II (AngII) induces the expression of suppressor of cytokine signaling (SOCS)-3 in rat hypothalamus - a mechanism for desensitization of AngII signaling.

scientific article published in April 2004

Antineoplastic effect of rapamycin is potentiated by inhibition of IRS-1 signaling in prostate cancer cells xenografts.

scientific article published on 9 February 2008

Antitumor effect of everolimus in a patient with type 3 gastric neuroendocrine tumor

scientific article published on 16 August 2013

Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRbeta/IRS-1 and Akt.

scientific article published in November 2009

Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats

scientific article (publication date: 30 July 2004)

Birth weight and type 2 diabetes in adults.

scientific article published in April 2009

Blood spotlight on leukocytes and obesity.

scientific article published on 24 September 2013

Chagasic Megaesophagus-Associated Carcinoma: Clinical Pattern and Outcomes

scientific article published on 01 August 2019

Circulating ghrelin concentrations are lowered by intracerebroventricular insulin.

scientific article published on 29 August 2006

Cross-talk between the insulin and leptin signaling systems in rat hypothalamus.

scientific article

Defective insulin and acetylcholine induction of endothelial cell-nitric oxide synthase through insulin receptor substrate/Akt signaling pathway in aorta of obese rats

scientific article published on 17 January 2007

Diacerhein improves glucose tolerance and insulin sensitivity in mice on a high-fat diet.

scientific article published on 6 September 2011

Disruption of metabolic pathways--perspectives for the treatment of cancer.

scientific article

Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice.

scientific article published on 4 September 2012

Effect of thiopental, pentobarbital and diethyl ether on early steps of insulin action in liver and muscle of the intact rat.

scientific article published in April 2005

Effects of NH4Cl intake on renal growth in rats: role of MAPK signalling pathway.

scientific article published on 16 September 2005

Exercise intensity, inflammatory signaling, and insulin resistance in obese rats.

scientific article published in December 2010

Fyn mediates leptin actions in the thymus of rodents

scientific article published on 3 November 2009

Gemcitabine-related thrombotic microangiopathy: a single-centre retrospective series.

scientific article

High-fat diet induces apoptosis of hypothalamic neurons

scientific article

Hypothalamic S1P/S1PR1 axis controls energy homeostasis.

scientific article published on 25 September 2014

Hypothalamic actions of tumor necrosis factor alpha provide the thermogenic core for the wastage syndrome in cachexia

scientific article published on 8 December 2009

Hypothalamic inflammation and the central nervous system control of energy homeostasis.

scientific article

Independent radiologic review in metastatic colorectal cancer: systematic review and meta-analysis.

scientific article published on April 2012

Infliximab restores glucose homeostasis in an animal model of diet-induced obesity and diabetes

scientific article published on 30 August 2007

Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats.

scientific article

Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet.

scientific article published on 11 September 2008

Insulin modulates leptin-induced STAT3 activation in rat hypothalamus.

scientific article published in July 2001

Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver.

scientific article published in January 2003

Intravesical bacillus Calmette-Guérin efficiently reduces p70S6K1 but not 4E-BP1 phosphorylation in nonmuscle invasive bladder cancer.

scientific article published on 6 September 2014

Local effectiveness and complications of neoadjuvant therapy in esophageal squamous cell carcinoma: radiotherapy versus chemoradiotherapy

scientific article published on 01 July 2011

Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth.

scientific article published on 4 May 2011

Metformin and blood cancers

scientific article published on 06 September 2018

Microbiota modification by probiotic supplementation reduces colitis associated colon cancer in mice.

scientific article

Modulation of IR/PTP1B interaction and downstream signaling in insulin sensitive tissues of MSG-rats

scientific journal article

Modulation of double-stranded RNA-activated protein kinase in insulin sensitive tissues of obese humans.

scientific article published on 11 June 2013

Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice.

scientific article published on 25 July 2012

Molecular and neuroendocrine mechanisms of cancer cachexia

scientific article

Myosteatosis in a systemic inflammation-dependent manner predicts favorable survival outcomes in locally advanced esophageal cancer

scientific article published on 01 October 2019

Novel signal transduction pathway for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and phosphoinositol 3-kinase/Akt pathways.

scientific article published in February 2003

Outcomes of COVID-19 Patients under Cytotoxic Cancer Chemotherapy in Brazil

scientific article published on 24 November 2020

Peroxisome proliferator-activated receptor gamma coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: a novel pathway for neural control of insulin secretion.

scientific article published on 24 October 2003

Pituitary carcinoma: A case report and discussion of potential value of combined use of Ga-68 DOTATATE and F-18 FDG PET/CT scan to better choose therapy.

scientific article published on August 2017

Prolactin-signal transduction in neonatal rat pancreatic islets and interaction with the insulin-signaling pathway.

scientific article published in May 2003

Reduction of hypothalamic protein tyrosine phosphatase improves insulin and leptin resistance in diet-induced obese rats

scientific article

Regulation of Cbl-associated protein/Cbl pathway in muscle and adipose tissues of two animal models of insulin resistance

scientific journal article

Reversal of diet-induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS-1 serine phosphorylation

scientific article published on 28 September 2006

S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance.

scientific article

Sarcopenia as an independent prognostic factor in patients with metastatic colorectal cancer: A retrospective evaluation

scientific article published on 16 April 2019

Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity

scientific journal article

Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats ⬇️

scientific article published on November 5, 2003

Squamous cell carcinoma of the stomach

scientific article published on 01 July 2014

TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.

scientific article published in December 2013

Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice.

scientific article published on 25 April 2006

Targeted disruption of inducible nitric oxide synthase protects against aging, S-nitrosation, and insulin resistance in muscle of male mice

scientific article published on 18 September 2012

Tear film and ocular surface changes in diabetes mellitus.

scientific article

The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance.

scientific article published on 4 September 2003

The incapacity of the surgeon to identify NASH in bariatric surgery makes biopsy mandatory

scientific article published on 01 December 2009

The role of neuronal AMPK as a mediator of nutritional regulation of food intake and energy homeostasis.

scientific article published on 14 August 2012

Tissue-specific regulation of early steps in insulin action in septic rats.

scientific article published in September 2001

Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trial

scientific article

Topiramate treatment improves hypothalamic insulin and leptin signaling and action and reduces obesity in mice.

scientific article published on 20 July 2012

Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity

scientific journal article

Zinc deficiency leading to intractable vomiting

scientific article published on 01 November 2002

[Insulin resistance/hyperinsulinemia associated diseases not included in the metabolic syndrome]

scientific article published on 01 April 2006

iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents

scientific article published on 23 August 2017

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