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List of works by Gabriela Alexe

A computational approach to predicting cell growth on polymeric biomaterials

scientific article published in April 2005

A robust meta-classification strategy for cancer detection from MS data

scientific article

Antigen availability determines CD8⁺ T cell-dendritic cell interaction kinetics and memory fate decisions

scientific article published on September 2013

Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia

scientific article published on 6 March 2018

Breast cancer prognosis by combinatorial analysis of gene expression data

scientific article

Breast cancer stratification from analysis of micro-array data of micro-dissected specimens.

scientific article

Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells

scientific article

Characterizing genomic alterations in cancer by complementary functional associations

scientific article published on 18 April 2016

Constructing near-perfect phylogenies with multiple homoplasy events

scientific article published in July 2006

Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia.

scientific article published in March 2018

Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

scientific article

Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in wild-type Ewing sarcoma

scientific article published on 25 July 2018

High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates

scientific article

High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma

scientific article published on 12 April 2019

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia

scientific article

Identification of a microRNA panel for clear-cell kidney cancer

scientific article published on 29 December 2009

Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

scientific article published in 2022

Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers ⬇️

scientific article published on October 1, 2010

Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma

scientific article

In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling

scientific article published on 13 June 2013

Increased SYK activity is associated with unfavorable outcome among patients with acute myeloid leukemia

scientific article

KLF5 controls glutathione metabolism to suppress p190-BCR-ABL+ B-cell lymphoblastic leukemia

Lactase Persistence and Lipid Pathway Selection in the Maasai ⬇️

scientific article published on September 28, 2012

Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis

scientific article

Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan

scientific article

Origin and differentiation of human memory CD8 T cells after vaccination

scientific article published on 13 December 2017

Ovarian cancer detection by logical analysis of proteomic data

scientific article

Portraits of breast cancer progression

scientific article

Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia

scientific article published on 26 November 2019

Robust diagnosis of non-Hodgkin lymphoma phenotypes validated on gene expression data from different laboratories

scientific article

SYK is a critical regulator of FLT3 in acute myeloid leukemia

scientific article

Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia

scientific article published on 9 November 2016

TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia

scientific article published on 3 October 2017

Targeting MTHFD2 in acute myeloid leukemia

scientific article published on 20 June 2016

Targeting MYCN in neuroblastoma by BET bromodomain inhibition

scientific article published on 21 February 2013

The Folate Cycle Enzyme MTHFR is a Critical Regulator of Cell Response to MYC-Targeting Therapies

scientific article published on 21 August 2020

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

scientific article

The genomic landscape of pediatric Ewing sarcoma

scientific article

The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia ⬇️

scientific article published on February 13, 2012

Tight Regulation of Memory CD8+ T Cells Limits Their Effectiveness during Sustained High Viral Load ⬇️

scientific article published on August 26, 2011

Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?

scientific article published on 09 October 2008

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

scientific article

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