List of works - Marcel Tijsterman

A Caenorhabditis elegans wild type defies the temperature-size rule owing to a single nucleotide polymorphism in tra-3.

scientific article

A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites

scientific article published in January 2014

A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis

scientific article (publication date: June 2012)

A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombination

scientific article

A versatile microsatellite instability reporter system in human cells

scientific article published on 16 July 2013

BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining

scientific article published on 17 July 2020

COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining

scientific article (publication date: 2013)

CRISPR/Cas9-targeted mutagenesis in Caenorhabditis elegans

scientific article published on 26 August 2013

Combined loss of three DNA damage response pathways renders C. elegans intolerant to light

scientific article published on 14 April 2017

Cosuppression in C. elegans

scientific article published on 01 June 2006

DNA double-strand break repair in Caenorhabditis elegans

scientific article

Defective Kin28, a subunit of yeast TFIIH, impairs transcription-coupled but not global genome nucleotide excision repair.

scientific article

Detection of si/miRNA in C. elegans by Northern Blot

scientific article published on 01 June 2006

Detection of siRNA in C. elegans Using RNase Protection

scientific article published on 01 June 2006

Dicers at RISC; the mechanism of RNAi

scientific article published on April 2004

Enzymatic detection of ultraviolet-induced pyrimidine (6-4) pyrimidone photoproducts at nucleotide resolution in Saccharomyces cerevisiae

scientific article published on 01 June 1998

FANCJ promotes DNA synthesis through G-quadruplex structures.

scientific article published on 5 September 2014

Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality

scholarly article

Genes Required for Systemic RNA Interference in Caenorhabditis elegans

article

Genomes and G-quadruplexes: for better or for worse.

scientific article published on 25 September 2013

Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining.

scientific article

Genomic instability and cancer: scanning the Caenorhabditis elegans genome for tumor suppressors

scientific article

Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability

scientific article published on 26 September 2016

Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi

scientific article published on July 2006

Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi

scientific article

Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA.

scientific article published on 7 July 2017

Introduction of Double-Stranded RNA in C. elegans by Feeding

scientific article published on 01 June 2006

Introduction of Double-Stranded RNA in C. elegans by Injection

scientific article published on 01 June 2006

Introduction of Double-Stranded RNA in C. elegans by Soaking

scientific article published on 01 June 2006

Isolation of RNA from C. elegans

scientific article published on 01 June 2006

Isolation of deletion alleles by G4 DNA-induced mutagenesis

scientific article published on 16 August 2009

Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi

scientific article published in August 2002

Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner

scientific article published on 16 January 2020

Mapping determinants of gene expression plasticity by genetical genomics in C. elegans

scientific article

Microhomology-mediated intron loss during metazoan evolution.

scientific article published on January 2013

Mosaic analysis and tumor induction in zebrafish by microsatellite instability-mediated stochastic gene expression

scientific article

Mutagenic Capacity of Endogenous G4 DNA Underlies Genome Instability in FANCJ-Defective C. elegans

scientific article published on 05 June 2008

Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers.

scientific article published on 13 November 2015

Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.

scientific article published on 27 October 2017

PPW-1, a PAZ/PIWI protein required for efficient germline RNAi, is defective in a natural isolate of C. elegans.

scientific article published in September 2002

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

scientific article

RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans

scientific article

RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs

scientific article published on 01 January 2002

Rad26, the yeast homolog of the cockayne syndrome B gene product, counteracts inhibition of DNA repair due to RNA polymerase II transcription.

scientific article published in January 1999

Saccharomyces cerevisiae mms19 mutants are deficient in transcription-coupled and global nucleotide excision repair.

scientific article published on October 1997

T-DNA integration in plants results from polymerase-θ-mediated DNA repair.

scientific article published on 31 October 2016

The Mechanism of RNA Interference and the Transposon Silencing in Caenorhabditis elegans.

scientific article published on 23 January 2002

The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α

scientific article published on 17 September 2007

The genetics of RNA silencing

scientific article (publication date: 2002)

The repair of G-quadruplex-induced DNA damage

scientific article published on September 2014

Transitions in the coupling of transcription and nucleotide excision repair within RNA polymerase II-transcribed genes of Saccharomyces cerevisiae ⬇️

scientific article published on July 22, 1997

List of works by Marcel Tijsterman

A Caenorhabditis elegans wild type defies the temperature-size rule owing to a single nucleotide polymorphism in tra-3.

A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites

A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis

A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombination

A versatile microsatellite instability reporter system in human cells

BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining

COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining

CRISPR/Cas9-targeted mutagenesis in Caenorhabditis elegans

Combined loss of three DNA damage response pathways renders C. elegans intolerant to light

Cosuppression in C. elegans

DNA double-strand break repair in Caenorhabditis elegans

Defective Kin28, a subunit of yeast TFIIH, impairs transcription-coupled but not global genome nucleotide excision repair.

Detection of si/miRNA in C. elegans by Northern Blot

Detection of siRNA in C. elegans Using RNase Protection

Dicers at RISC; the mechanism of RNAi

Enzymatic detection of ultraviolet-induced pyrimidine (6-4) pyrimidone photoproducts at nucleotide resolution in Saccharomyces cerevisiae

FANCJ promotes DNA synthesis through G-quadruplex structures.

Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality

Genes Required for Systemic RNA Interference in Caenorhabditis elegans

Genomes and G-quadruplexes: for better or for worse.

Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining.

Genomic instability and cancer: scanning the Caenorhabditis elegans genome for tumor suppressors

Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability

Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi

Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi

Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA.

Introduction of Double-Stranded RNA in C. elegans by Feeding

Introduction of Double-Stranded RNA in C. elegans by Injection

Introduction of Double-Stranded RNA in C. elegans by Soaking

Isolation of RNA from C. elegans

Isolation of deletion alleles by G4 DNA-induced mutagenesis

Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi

Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner

Mapping determinants of gene expression plasticity by genetical genomics in C. elegans

Microhomology-mediated intron loss during metazoan evolution.

Mosaic analysis and tumor induction in zebrafish by microsatellite instability-mediated stochastic gene expression

Mutagenic Capacity of Endogenous G4 DNA Underlies Genome Instability in FANCJ-Defective C. elegans

Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers.

Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.

PPW-1, a PAZ/PIWI protein required for efficient germline RNAi, is defective in a natural isolate of C. elegans.

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans

RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs

Rad26, the yeast homolog of the cockayne syndrome B gene product, counteracts inhibition of DNA repair due to RNA polymerase II transcription.

Saccharomyces cerevisiae mms19 mutants are deficient in transcription-coupled and global nucleotide excision repair.

T-DNA integration in plants results from polymerase-θ-mediated DNA repair.

The Mechanism of RNA Interference and the Transposon Silencing in Caenorhabditis elegans.

The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α

The genetics of RNA silencing

The repair of G-quadruplex-induced DNA damage

Transitions in the coupling of transcription and nucleotide excision repair within RNA polymerase II-transcribed genes of Saccharomyces cerevisiae ⬇️