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List of works by Noriko Gotoh

A highly conserved tyrosine residue at codon 845 within the kinase domain is not required for the transforming activity of human epidermal growth factor receptor

scientific article published on July 31, 1992

Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

scientific article published on 22 August 2016

Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis

scientific article

An FGF4-FRS2alpha-Cdx2 axis in trophoblast stem cells induces Bmp4 to regulate proper growth of early mouse embryos.

scientific article published in January 2010

Collocation-based sparse estimation for constructing dynamic gene networks

scientific article published on January 1, 2010

Cyclin G2: A novel independent prognostic marker in pancreatic cancer

scientific article published on 2 September 2015

Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway

scientific article published on 26 March 2021

Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma

scientific article published on 29 May 2013

Direct activation of telomerase by EGF through Ets-mediated transactivation of TERT via MAP kinase signaling pathway.

scientific article

Discrimination between phosphotyrosine-mediated signaling properties of conventional and neuronal Shc adapter molecules.

scientific article published in January 2002

Drug discovery of anticancer drugs targeting methylenetetrahydrofolate dehydrogenase 2

Effect of in vivo administration of reprogramming factors in the mouse liver

scientific article published on 20 June 2013

Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming.

scientific article published on 15 July 2015

Epidermal growth factor receptor tyrosine kinase defines critical prognostic genes of stage I lung adenocarcinoma

scientific article

Epiregulin enhances tumorigenicity by activating the ERK/MAPK pathway in glioblastoma

scientific article

Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells

scientific journal article

FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation.

scientific article published on 23 January 2014

FRS2 alpha 2F/2F mice lack carotid body and exhibit abnormalities of the superior cervical sympathetic ganglion and carotid sinus nerve.

scientific article

Feedback inhibitors of the epidermal growth factor receptor signaling pathways.

scientific article published on 09 August 2008

Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development

scientific article published on 27 November 2013

Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms

scientific article published on 20 July 2009

Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas

scientific article published on 11 November 2011

Identifying regulational alterations in gene regulatory networks by state space representation of vector autoregressive models and variational annealing.

scientific article

Inflammatory signaling pathways in self-renewing breast cancer stem cells.

scientific article published on December 2010

Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer.

scientific article

Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR

scientific article

Long-term Inflammation Transforms Intestinal Epithelial Cells of Colonic Organoids.

scientific article published in May 2017

MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells

scientific article published on 19 December 2020

Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.

scientific article published on 07 December 2016

MicroRNAs Induce Epigenetic Reprogramming and Suppress Malignant Phenotypes of Human Colon Cancer Cells

scientific article published on 13 May 2015

Mint3 depletion restricts tumor malignancy of pancreatic cancer cells by decreasing SKP2 expression via HIF-1

scientific article published on 21 August 2020

Oncogenic Fusion Gene CD74-NRG1 Confers Cancer Stem Cell-like Properties in Lung Cancer through a IGF2 Autocrine/Paracrine Circuit.

scientific article published on 2 February 2016

Patient-Derived Xenograft Models of Breast Cancer and Their Application

scientific article published on 20 June 2019

Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling

scientific article

Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic study ⬇️

scientific article published on September 3, 2011

Pyruvate kinase M2, but not M1, allele maintains immature metabolic states of murine embryonic stem cells

scientific article published on 09 March 2015

Recent understanding of the molecular mechanisms for the efficacy and resistance of EGF receptor-specific tyrosine kinase inhibitors in non-small cell lung cancer.

scientific article published on 05 July 2012

Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition.

scientific article

SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation.

scientific article

The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.

scientific article

The acquisition of malignant potential in colon cancer is regulated by the stabilization of Atonal homolog 1 protein.

scientific article published on 16 January 2013

The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development

scientific journal article

Tyrosine Residues 239 and 240 of Shc Are Phosphatidylinositol 4,5-Bisphosphate-Dependent Phosphorylation Sites by c-Src ⬇️

scientific article published on November 17, 1997

Upregulation of S100A10 in metastasized breast cancer stem cells

scientific article published on 25 September 2020

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